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Rachel W Kasinskas

from East Kingston, NH
Age ~47
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Also known as:
Rachel W Lasinskas
Phone and address:
31 North Rd, South Hampton, NH 03827
(978) 388-0534
Related to:
Kerrie A Mcdonough, 51Maria Jose Wantuil, 75
Connected to:
Anna K Kasior, 49Randy B Kasir, 46Chander Kasiraj, 70Regina G Kasiri, 69Stuart P Kasiske, 51Sara M Kasiski, 76Christine M Kasitz, 39Jesse P Kasitz, 49Ashok Kasiviswanathan, 41Anne M Kask, 85

Rachel Kasinskas Phones & Addresses

  • 31 North Rd, East Kingston, NH 03827 (978) 388-0534
  • 97 Market St, Amesbury, MA 01913 (978) 388-0534
  • Nottingham, NH
  • Notre Dame, IN
  • Amherst, MA
  • Meriden, CT
  • Galloway, OH

Work

Company: Roche Mar 2016 Position: Director, support and applications

Education

School / High School: University of Massachusetts, Amherst 2001 to 2007

Industries

Biotechnology

Resumes

Resumes

Rachel Kasinskas Photo 1

Director, Support And Applications

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Location:
Amesbury, MA
Industry:
Biotechnology
Work:
Roche
Director, Support and Applications
Kapa Biosystems
Director of Scientific Support and Applications
Kapa Biosystems May 2013 - May 2014
Scientific Support and Applications Manager
Life Technologies Apr 2012 - Feb 2013
Senior Manager
Life Technologies Jan 2010 - Feb 2013
Amplification Technology Group Leader
Education:
University of Massachusetts, Amherst 2001 - 2007

Publications

Us Patents

Salmonella Cancer Therapeutics And Related Therapeutic Methods

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US Patent:
20090175829, Jul 9, 2009
Filed:
Nov 17, 2008
Appl. No.:
12/313052
Inventors:
NEIL S. FORBES - BELCHERTOWN MA, US
RACHEL W. KASINSKAS - EAST KINGSTON NH, US
International Classification:
A61K 35/74
C12N 5/08
C12Q 1/37
US Classification:
424 932, 435375, 435 23
Abstract:
Therapeutic methods for treatment of solid tumor cancer cell masses, as can be effected using therapeutic compositions comprising species/strains and related compositions.

Multipurpose Microfluidic Device For Mimicking A Microenvironment Within A Tumor

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US Patent:
20110081664, Apr 7, 2011
Filed:
Oct 16, 2009
Appl. No.:
12/580592
Inventors:
Neil St. John Forbes - Belchertown MA, US
Rachel W. Kasinskas - Amesbury MA, US
Colin L. Walsh - San Francisco CA, US
Brett M. Babin - Chester NH, US
Bhushan J. Toley - Amherst MA, US
Assignee:
University of Massachusetts - Boston MA
International Classification:
G01N 33/53
C12M 3/00
C12M 3/06
C12N 5/071
C12Q 1/06
US Classification:
435 723, 4352891, 4353031, 435325, 435 39, 435 721, 435 724
Abstract:
The present application relates generally to a novel microfluidic device for the in it propagation of neoplastic cellagregates under conditions that mimic the physiological microenvironment found in tumors. The invention also describes methods of screening for therapeutic test agents and protocols that target proliferating and quiescent neoplastic cells within tumors.

Clonal Amplification Of Nucleic Acid On Solid Surface With Template Walking

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US Patent:
20120156728, Jun 21, 2012
Filed:
Dec 16, 2011
Appl. No.:
13/328844
Inventors:
Bin Li - Palo Alto CA, US
Kai Lao - Pleasanton CA, US
Jennifer O'Neil - Peabody MA, US
Jennifer Kunkel - Amesbury MA, US
Kellie Haley - Peabody MA, US
Rachel Kasinskas - Amesbury MA, US
Zhaochun Ma - Sunnyvale CA, US
Pius Brzoska - Woodside CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
C12P 19/34
US Classification:
435 911
Abstract:
Novel methods of generating a localized population of immobilized clonal amplicons on a support are provided.

Methods, Compositions, Systems, Apparatuses And Kits For Nucleic Acid Amplification

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US Patent:
20130203607, Aug 8, 2013
Filed:
Mar 14, 2013
Appl. No.:
13/828049
Inventors:
Life Technologies Corporation - Carlsbad CA, US
Kai Qin LAO - Pleasanton CA, US
Jennifer O'NEIL - Peabody MA, US
Jennifer KUNKEL - Amesbury MA, US
Kellie HALEY - Peabody MA, US
Rachel KASINSKAS - Amesbury MA, US
Zhaochun MA - Sunnyvale CA, US
Pius BRZOSKA - Woodside CA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
C12Q 1/68
US Classification:
506 2, 435 612
Abstract:
In some embodiments, the present teachings provide methods for paired end sequencing. In some embodiment, a polynucleotide template to be subjected to paired end sequencing comprises at least one cross linking moiety and at least one scissile moiety. In some embodiments, a paired end sequencing reaction comprises (a) a forward sequencing step, (b) a cleavage step, and (c) a reverse sequencing step. In some embodiments, a paired end sequencing reaction comprises (a) a forward sequencing step, (b) a cross-linking step, (c) a cleavage step, and (d) a reverse sequencing step.

Nucleic Acid Amplification

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US Patent:
20130225421, Aug 29, 2013
Filed:
Mar 15, 2013
Appl. No.:
13/842296
Inventors:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA, US
David RUFF - San Francisco CA, US
Shiaw-Min CHEN - Fremont CA, US
Jennifer O'NEIL - Peabody MA, US
Rachel KASINSKAS - Amesbury MA, US
Jonathan ROTHBERG - Guilford CT, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
C12Q 1/68
US Classification:
506 2, 506 26
Abstract:
In some embodiments, the present teachings provide methods for nucleic acid amplification, comprising forming a reaction mixture, and subjecting the reaction mixture to conditions suitable for nucleic acid amplification. In some embodiments, methods for nucleic acid amplification include subjecting the nucleic acid to be amplified to partially denaturing conditions. In some embodiments, methods for nucleic acid amplification include amplifying without fully denaturing the nucleic acid that is amplified. In some embodiments, the methods for nucleic acid amplification employ an enzyme that catalyzes homologous recombination and a polymerase. In some embodiments, methods for nucleic acid amplification can be conducted in a single reaction vessel. In some embodiments, methods for nucleic acid amplification can be conducted in a single continuous liquid phase of a reaction mixture, without need for compartmentalization of the reaction mixture or immobilization of reaction components. In some embodiments, methods for nucleic acid amplification comprise a amplifying at least one polynucleotide onto a surface under isothermal amplification conditions, optionally in the presence of a polymer. The polymer can include a sieving agent and/or a diffusion-reducing agent.

Nucleic Acid Amplification

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US Patent:
20130281307, Oct 24, 2013
Filed:
Jun 20, 2013
Appl. No.:
13/923232
Inventors:
David RUFF - San Francisco CA, US
Jennifer O'NEIL - Peabody MA, US
Rachel KASINSKAS - Amesbury MA, US
Shiaw-Min CHEN - Fremont CA, US
Jonathan ROTHBERG - Guilford CT, US
International Classification:
C12Q 1/68
US Classification:
506 2, 506 26
Abstract:
In some embodiments, the present teachings provide methods for nucleic acid amplification, comprising forming a reaction mixture, and subjecting the reaction mixture to conditions suitable for nucleic acid amplification. In some embodiments, methods for nucleic acid amplification include subjecting the nucleic acid to be amplified to partially denaturing conditions. In some embodiments, methods for nucleic acid amplification include amplifying without fully denaturing the nucleic acid that is amplified. In some embodiments, the methods for nucleic acid amplification employ an enzyme that catalyzes homologous recombination and a polymerase. In some embodiments, methods for nucleic acid amplification can be conducted in a single reaction vessel. In some embodiments, methods for nucleic acid amplification can be conducted in a single continuous liquid phase of a reaction mixture, without need for compartmentalization of the reaction mixture or immobilization of reaction components. In some embodiments, methods for nucleic acid amplification comprise a amplifying at least one polynucleotide onto a surface under isothermal amplification conditions, optionally in the presence of a polymer. The polymer can include a sieving agent and/or a diffusion-reducing agent.

Methods And Kits For Breaking Emulsions

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US Patent:
20140024040, Jan 23, 2014
Filed:
Apr 5, 2012
Appl. No.:
14/110695
Inventors:
Jeffrey Sabina - North Haven CT, US
Ilya Zlatkovsky - San Francisco CA, US
Rachel Kasinskas - Amesbury MA, US
Assignee:
LIFE TECHNOLOGIES CORPORATION - Carlsbad CA
International Classification:
C07H 21/00
C07K 1/14
US Classification:
435 612, 536 231, 5303871, 530399, 530422, 435183
Abstract:
The disclosure relates generally to methods, systems, compositions and kits for breaking a water-in-oil emulsion including one or more biomolecules dispersed in an aqueous phase of the water-in-oil emulsion. In some embodiments, the disclosure relates to obtaining a first emulsion including a continuous hydrophobic fraction and a discontinuous aqueous fraction, the aqueous fraction having one or more biomolecules dispersed therein, breaking the first emulsion by contacting the first emulsion with a breaking solution including a second emulsion, where the second emulsion includes a discontinuous phase of organic extraction solvent dispersed in a continuous aqueous phase, and centrifuging to separate the phases of the resulting mixture. In some embodiments, the disclosure relates generally to methods, kits and systems for extracting biomolecules from a water-in-oil emulsion, including breaking a water-in-oil emulsion comprising a plurality of aqueous droplets in a continuous hydrophobic fraction using a breaking solution to produce a resulting reaction mixture containing one or more biomolecules and manipulating the resulting reaction mixture to form at least two phases, where one of the phases includes an aqueous phase containing the one or more biomolecules.

Nucleic Acid Amplification

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US Patent:
20140080717, Mar 20, 2014
Filed:
Sep 10, 2013
Appl. No.:
14/023361
Inventors:
David RUFF - San Francisco CA, US
Shiaw-Min CHEN - Fremont CA, US
Jennifer O'NEIL - Peabody MA, US
Rachel KASINSKAS - Amesbury MA, US
Jonathan ROTHBERG - Guilford CT, US
Wolfgang HINZ - Killingworth CT, US
Assignee:
Life Technologies Corporation - Carlsbad CA
International Classification:
C12Q 1/68
US Classification:
506 2, 506 26
Abstract:
In some embodiments, the present teachings provide methods for nucleic acid amplification, comprising forming a reaction mixture, and subjecting the reaction mixture to conditions suitable for nucleic acid amplification. In some embodiments, methods for nucleic acid amplification include subjecting the nucleic acid to be amplified to partially denaturing conditions. In some embodiments, methods for nucleic acid amplification include amplifying without fully denaturing the nucleic acid that is amplified. In some embodiments, the methods for nucleic acid amplification employ an enzyme that catalyzes homologous recombination and a polymerase. In some embodiments, methods for nucleic acid amplification can be conducted in a single reaction vessel. In some embodiments, methods for nucleic acid amplification can be conducted in a single continuous liquid phase of a reaction mixture, without need for compartmentalization of the reaction mixture or immobilization of reaction components. In some embodiments, methods for nucleic acid amplification comprise a amplifying at least one polynucleotide onto a surface under isothermal amplification conditions, optionally in the presence of a polymer. The polymer can include a sieving agent and/or a diffusion-reducing agent.
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Rachel W Kasinskas from East Kingston, NH, age ~47 Get Report