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Yanbin Liu

from Acton, MA
Age ~61
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Also known as:
Yan Bin Liu, Yan B Liu, Yan-Bin Liu, Liu Yanbin, Lou Yanbin, Liu Yan-Bin, Lou Yambin
Phone and address:
103 Canterbury Hill Rd, Acton, MA 01720
(978) 929-2542
Related to:
Quan J Chen, 58
Connected to:
Abby Liu, 37Alba Liu, 48Alina Y Liu, 53Annan R Liu, 53Antong Liu, 35Anwei Liu, 62Bai Liu, 66Bao Liu, 51Baoxian Liu, 55Bella C Liu, 101

Yanbin Liu Phones & Addresses

  • 103 Canterbury Hill Rd, Acton, MA 01720 (978) 929-2542
  • 5 Conant St, Acton, MA 01720 (978) 929-2542
  • Bedford, MA
  • Flemington, NJ
  • Lawrence, KS
  • Marlborough, MA
  • Highland Park, NJ
  • Piscataway, NJ
  • Edison, NJ
  • Hudson, MA

Work

Position: Sales Occupations

Education

Degree: High school graduate or higher

Publications

Us Patents

Raf Inhibitors And Their Uses

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US Patent:
7501430, Mar 10, 2009
Filed:
Apr 16, 2007
Appl. No.:
11/785163
Inventors:
Jean-Marc Lapierre - Pelham NH, US
Nivedita D. Namdev - Westford MA, US
Mark A. Ashwell - Carlisle MA, US
Dennis S. France - Carlisle MA, US
Hui Wu - Malden MA, US
Patrick M. Hutchins - Denver CO, US
Manish Tandon - Framingham MA, US
Yanbin Liu - Acton MA, US
Jeff S. Link - Londonderry NH, US
Syed M. Ali - North Andover MA, US
Chris J. Brassard - Somerville MA, US
Robb B. Nicewonger - Tyngsboro MA, US
Anton Filikov - Stoneham MA, US
Rebecca J. Carazza - Winchester MA, US
Assignee:
ArQule, Inc. - Woburn MA
International Classification:
C07D 498/04
C07D 513/04
A61K 31/429
A61K 31/4188
US Classification:
514275, 544333
Abstract:
The present invention provides imidazooxazole and imidazothiazole compounds and their synthesis. The compounds of the present invention are capable of inhibiting the activity of RAF kinase, such as B-RAF. The compounds are useful for the treatment of cell proliferative disorders such as cancer.

Pharmaceutical Compositions Of Β-Lapachone And Β-Lapachone Analogs With Improved Tumor Targeting Potential

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US Patent:
7812051, Oct 12, 2010
Filed:
Aug 11, 2005
Appl. No.:
11/201097
Inventors:
Mark A. Ashwell - Carlisle MA, US
Chiang J. Li - West Roxbury MA, US
Manish Tandon - Framingham MA, US
Yanbin Liu - Acton MA, US
Jean-Marc LaPierre - Pelham NH, US
Zhiwei Jiang - Stow MA, US
Assignee:
ArQule, Inc. - Woburn MA
International Classification:
A61K 31/352
C07D 311/92
US Classification:
514454, 514455, 424423, 549389
Abstract:
The present invention relates to polymer-modified quinone-containing and carbonyl-containing therapeutic agents, including polymer-modified β-lapachone compounds, and methods of treating cancer by administering the polymer-modified therapeutic agents to a subject. Polymer-modification of therapeutic agents, such as β-lapachone compounds, provides effective transport of polymer-modified therapeutic agents to tumor cells or tumor tissues by exploiting the EPR effect in tumor tissues.

1,4-Disubstituted Naphthalenes As Inhibitors Of P38 Map Kinase

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US Patent:
7829560, Nov 9, 2010
Filed:
Jul 8, 2005
Appl. No.:
11/631617
Inventors:
Mark A. Ashwell - Carlisle MA, US
Yanbin Liu - Acton MA, US
Syed Ali - North Andover MA, US
Jason Hill - Auburndale MA, US
Woj Wrona - Waltham MA, US
Assignee:
Arqule, Inc. - Woburn MA
International Classification:
C07D 413/12
C07D 239/34
A61K 31/5355
A61K 31/506
A61K 31/505
A61P 29/00
A61P 19/02
C07D 413/14
C07D 265/28
C07D 273/01
C07D 295/073
C07D 239/47
C07D 211/06
C07D 213/56
A61K 31/5375
A61K 31/4453
A61K 31/55
US Classification:
5142358, 514272, 5142392, 5142322, 5142342, 5142355, 514319, 51421705, 514357, 544123, 544321, 544131, 544 79, 544 70, 544121, 544165, 544129, 544230, 544273, 546206, 546194, 546337, 540598
Abstract:
1,4 disubstituted napthylenes, of formula (I), are disclosed. These compounds may be useful in treating cell-proliferative diseases.

Inhibitors Of P38 And Methods Of Using The Same

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US Patent:
7902192, Mar 8, 2011
Filed:
May 14, 2004
Appl. No.:
10/556161
Inventors:
Mark A. Ashwell - Carlisle MA, US
Syed Ali - North Andover MA, US
Jifeng Liu - Winchester MA, US
Yanbin Liu - Acton MA, US
Peter Lohse - Weston MA, US
Belew Mekonnen - Gilbertsville PA, US
Robert Selliah - Midvale UT, US
Manish Tandon - Framingham MA, US
Woj Wrona - Waltham MA, US
Valery Antonenko - Cupertino CA, US
Assignee:
ArQule, Inc. - Woburn MA
International Classification:
C07D 498/04
A61K 31/41
US Classification:
5142358, 514274, 514275, 544122, 544310, 544333
Abstract:
In general, the present invention relates to compounds capable of inhibiting p38, methods for inhibiting p38 in vivo or in vitro, and methods for treating conditions associated with p38 activity or cytokine activity.

Lapachone Compounds And Methods Of Use Thereof

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US Patent:
8067459, Nov 29, 2011
Filed:
Oct 16, 2008
Appl. No.:
12/252681
Inventors:
Mark Ashwell - Carlisle MA, US
Manish Tandon - Framingham MA, US
Jean-Marc Lapierre - Pelham NH, US
Syed Ali - North Andover MA, US
Yanbin Liu - Acton MA, US
Chiang J. Li - Cambridge MA, US
Assignee:
ArQule, Inc. - Woburn MA
International Classification:
A61K 31/39
C07D 327/02
US Classification:
514431, 514434, 549 10, 549 16
Abstract:
The invention provides lapachone analogs and derivatives as well as methods of use thereof. These compounds can be used in pharmaceutical compositions for the treatment or prevention of cell proliferation disorders. These compounds can also be used in the treatment or prevention of cancer or precancerous conditions.

1,4-Disubstituted Naphthalenes As Inhibitors Of P38 Map Kinase

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US Patent:
8114873, Feb 14, 2012
Filed:
Aug 11, 2010
Appl. No.:
12/854687
Inventors:
Mark A. Ashwell - Carlisle MA, US
Yanbin Liu - Acton MA, US
Syed M. Ali - North Andover MA, US
Jason Hill - Auburndale MA, US
Woj Wrona - Waltham MA, US
Assignee:
ArQule, Inc. - Woburn MA
International Classification:
A61K 31/5355
A61K 31/5375
C07D 265/30
A61P 29/00
US Classification:
5142382, 544106
Abstract:
Naphthalene-based compounds having linked heterocyclic and aromatic rings capable of inhibiting P38, methods for inhibiting P38 in vivo or in vitro, diagnostics for determining activity in the treatment of P38 and/or cytokine-associated conditions and methods for treating conditions associated with P38 activity or cytokine activity; more particularly naphthalene-based compounds of Formula (I) having a morpholine heterocyclic ring, and methods of use thereof.

Pyrrolidinone, Pyrrolidine-2,5-Dione, Pyrrolidine And Thiosuccinimide Derivatives, Compositions And Methods For Treatment Of Cancer

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US Patent:
8304425, Nov 6, 2012
Filed:
Jun 19, 2008
Appl. No.:
12/664550
Inventors:
Jianqiang Wang - Acton MA, US
Syed M. Ali - North Andover MA, US
Eugene Kelleher - Wellesley MA, US
Yanbin Liu - Acton MA, US
Jason Hill - Auburndale MA, US
Mark A. Ashwell - Carlisle MA, US
Assignee:
ArQule, Inc. - Woburn MA
International Classification:
A01N 43/42
A61K 31/44
US Classification:
514294, 546 94
Abstract:
The present invention relates to pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosucciniroide compounds of formulae (I)-(IV), and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound of pyrrolidin-2-one, pyrrolidin-2,5-dione, pyrrolidine and thiosuccinimide compound of the present invention.

Substituted Dipyrido-Pyrimido-Diazepine And Benzo-Pyrido-Pyrimido Compounds

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US Patent:
8349827, Jan 8, 2013
Filed:
Mar 31, 2010
Appl. No.:
12/751332
Inventors:
Manish Tandon - Framingham MA, US
Yanbin Liu - Acton MA, US
Nivedita Namdev - Westford MA, US
Mark A. Ashwell - Carlisle MA, US
Rocio Palma - North Andover MA, US
Assignee:
ArQule, Inc. - Woburn MA
International Classification:
A61P 35/00
A61K 31/519
C07D 471/14
C07D 471/22
US Classification:
514215, 540578
Abstract:
The present invention relates to substituted dipyrido-pyrimido-diazepine compounds, substituted benzo-pyrido-pyrimido-diazepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted dipyrido-pyrimido-diazepine compounds, substituted benzo-pyrido-pyrimido-diazepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
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Yanbin Liu from Acton, MA, age ~61 Get Report