Inventors:
Gafur Zainiev - West Bloomfield MI, US
Inlik Zainiev - West Bloomfield MI, US
Timur Zainiev - West Bloomfield MI, US
International Classification:
C12P 21/00
C12M 1/00
C12P 19/34
US Classification:
435 681, 4352891, 435 915
Abstract:
A process and apparatus for self-assembling a number of elements and determining their sequence is provided. In the field of DNA analysis, an iterative process is disclosed wherein an apparatus with a set of reaction chambers in which a species of recognition element nucleotides are differentially added and subjected to a polymerization reaction allows recognition of which species is next in sequence on a template strand as measured by a detector in a detection area. Fractional concentration stepwise addition of the identified species then determines if an element repeat exists. The position in the sequence is then completed by addition of a saturating amount of building element to complete the polymerization reaction on all structure strands. The process is repeated until the entire structure is complete and the sequence identified.