Katariina Hutterer Phones & Addresses
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3451 Louis Dr, Newbury Park, CA 91320
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Thousand Oaks, CA
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653 Mission Canyon Rd, Santa Barbara, CA 93105 (805) 898-0116
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215 Vance St, Chapel Hill, NC 27516
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1720 Halford Ave, Santa Clara, CA 95051
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Mountain View, CA
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Oxnard, CA
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Ventura, CA
Publications
Us Patents
Multiplexed Capillary Electrophoresis Systems
View pageUS Patent:
20050161329, Jul 28, 2005
Filed:
Apr 14, 2003
Appl. No.:
10/511282
Inventors:
Katariina Hutterer - Santa Barbara CA, US
Nels Olson - La Jolla CA, US
Stevan Jovanovich - Livermore CA, US
Thomas Armstrong - Santa Clara CA, US
Dean Burgi - Sunnyvale CA, US
Vladislav Dolnik - Mountain View CA, US
Nels Olson - La Jolla CA, US
Stevan Jovanovich - Livermore CA, US
Thomas Armstrong - Santa Clara CA, US
Dean Burgi - Sunnyvale CA, US
Vladislav Dolnik - Mountain View CA, US
International Classification:
G01N027/453
US Classification:
204456000, 204605000
Abstract:
Multi-capillary systems for high-throughput electrophoretic separation and detection of biomolecules are disclosed. One embodiment of the invention uses galactomannans as a size-sieving matrix for multi-channel electrophoretic separations of biomolecules. Multi-color detection for the simultaneous analysis of controls and standards in the same channels as the samples, and endogenous fluorescence detection are also disclosed. Another embodiment of the invention is a two dimensional system for separation of complex samples, using multiplexed capillary electrophoresis system as the second dimension, with a fraction collection step connecting the two separation steps. The systems allow for separations to be accomplished with a highly parallel manner, or in a two-dimensional format.