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Junhua Fan

from San Diego, CA
Age ~53
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Also known as:
Li Fan, Junhua Li, Jun Hua Li
Phone and address:
12217 Caminito Mira Del Mar, San Diego, CA 92130
Related to:
Xiaoshuang WangTsunghan LeeDiana J Lee, 37Weizhong Li, 57Weighong LeeYuan Shao, 52Li Li, 52Lan Wang, 67Xifeng Yang
Connected to:
Angus Y Fan, 44Anny Fan, 28Bessy W Fan, 70Bin Fan, 53Chieh-Min Fan, 61Chien C Fan, 74Christine N Fan, 36Chunbo B Fan, 49Dongmei Fan, 44Eugene Fan, 46

Junhua Fan Phones & Addresses

  • 12217 Caminito Mira Del Mar, San Diego, CA 92130
  • 7528 Charmant Dr, San Diego, CA 92122

Work

Company: Annova chem Feb 2011 Position: Cofounder

Skills

Drug Discovery • Biotechnology • Hplc • Chromatography • Purification • Biopharmaceuticals • Lifesciences • Analytical Chemistry • Medicinal Chemistry • Organic Synthesis • Chemistry • Nmr • Lc Ms

Industries

Biotechnology

Resumes

Resumes

Junhua Fan Photo 1

Cofounder

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Location:
San Diego, CA
Industry:
Biotechnology
Work:
Annova Chem
Cofounder
Biogen May 2006 - Jan 2011
Research Chemist
Conforma Therapeutics Oct 2001 - May 2006
Research Chemist
Skills:
Drug Discovery
Biotechnology
Hplc
Chromatography
Purification
Biopharmaceuticals
Lifesciences
Analytical Chemistry
Medicinal Chemistry
Organic Synthesis
Chemistry
Nmr
Lc Ms

Publications

Us Patents

Ansamycins Having Improved Pharmacological And Biological Properties

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US Patent:
7465718, Dec 16, 2008
Filed:
Feb 10, 2003
Appl. No.:
10/503880
Inventors:
Lin Zhang - San Diego CA, US
Jean-Yves Le Brazidec - San Diego CA, US
Lawrence C. Fritz - Rancho Santa Fe CA, US
Francis J. Burrows - Solana Beach CA, US
Marcus F. Boehm - San Diego CA, US
Junhua Fan - San Diego CA, US
Sean Konrad McHugh - Ingleside IL, US
Assignee:
Conforma Therapeutics Corporation - San Diego CA
International Classification:
C07D 233/14
A61K 31/33
US Classification:
514183, 5142315, 51425213, 514308, 514339, 514359, 514361, 514378, 514403, 514422, 514444, 514471, 540456
Abstract:
Ansamycins and methods of preparing and using the same are described. At least some of these ansamycins exhibit one or more of improved aqueous formulation ability, chemical stability, and bioavailability. Some of the derivatives described are dimers. These and others described can include one or more solubilizing groups that have expected merit in rendering the overall compounds useful as drugs and prodrugs.

Purine Analogs Having Hsp90-Inhibiting Activity

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US Patent:
20050049263, Mar 3, 2005
Filed:
Oct 30, 2002
Appl. No.:
10/494414
Inventors:
Srinivas Kasibhatla - San Diego CA, US
Kevin Hong - San Diego CA, US
Lin Zhang - San Diego CA, US
Marco Biamonte - San Diego CA, US
Marcus Boehm - San Diego CA, US
Jiandong Shi - San Diego CA, US
Junhua Fan - San Diego CA, US
International Classification:
A61K031/53
A61K031/522
A61K031/52
US Classification:
514263210, 514263220, 514263370, 514263400, 544276000, 544277000
Abstract:
Novel purine compounds and tautomers and pharmaceutically acceptable salts thereof are described, as are pharmaceutical compositions comprising the same, complexes comprising the same, e.g., HSP90 complexes, and methods of using the same.

Orally Active Purine-Based Inhibitors Of Heat Shock Protein 90

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US Patent:
20070129334, Jun 7, 2007
Filed:
Dec 18, 2006
Appl. No.:
11/612418
Inventors:
Srinivas Kasibhatla - San Diego CA, US
Lin Zhang - San Diego CA, US
Marco Biamonte - San Diego CA, US
Marcus Boehm - San Diego CA, US
Junhua Fan - San Diego CA, US
Jiandong Shi - San Diego CA, US
Kevin Hong - San Diego CA, US
Assignee:
CONFORMA THERAPEUTICS CORPORATION - San Diego CA
International Classification:
A61K 31/675
C07D 473/00
C07D 473/12
US Classification:
514081000, 514263200, 514263300, 544244000, 544276000
Abstract:
Novel purine compounds and tautomers and pharmaceutically acceptable salts thereof are described, as are pharmaceutical compositions comprising the same, complexes comprising the same, e.g., HSP90 complexes, and methods of using the same. Methods of using the novel purine compounds of the invention, and tautomers and pharmaceutically acceptable salts thereof, include their use in inhibiting heat shock protein 90's (HSP90's) to thereby treat or prevent HSP90-dependent diseases, e.g., proliferative disorders such as breast cancer.

Purine Analogs Having Hsp90-Inhibiting Activity

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US Patent:
20080125446, May 29, 2008
Filed:
Jul 2, 2007
Appl. No.:
11/772496
Inventors:
Srinivas Rao Kasibhatla - San Diego CA, US
Kevin Hong - San Diego CA, US
Lin Zhang - San Diego CA, US
Marco Antonio Biamonte - San Diego CA, US
Marcus F. Boehm - San Diego CA, US
Jiandong Shi - San Diego CA, US
Junhua Fan - San Diego CA, US
International Classification:
A61K 31/52
C07D 473/34
C07K 14/47
C12N 5/06
US Classification:
5142634, 544277, 530409, 435375
Abstract:
Novel purine compounds and tautomers and pharmaceutically acceptable salts thereof are described, as are pharmaceutical compositions comprising the same, complexes comprising the same, e.g., HSP90 complexes, and methods of using the same.

Modulators Of Mitotic Kinases

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US Patent:
20100190787, Jul 29, 2010
Filed:
Jan 30, 2008
Appl. No.:
12/525155
Inventors:
Srinivas Rao Kasibhatla - San Diego CA, US
Kevin Hong - San Diego CA, US
Lin Zhang - San Diego CA, US
Marcus F. Boehm - San Diego CA, US
Junhua Fan - San Diego CA, US
Jean-Yves LeBrazidec - San Diego CA, US
International Classification:
A61K 31/5377
C07D 473/00
A61K 31/52
C07D 413/02
US Classification:
5142342, 544277, 5142634, 544118
Abstract:
The invention relates to compounds of Formula (I), a prodrug, a polymorph, a tautomer, an enantiomer, a stereoisomer, a solvate, an N-oxide, or a pharmaceutically acceptable salt thereof: (formula should be inserted here) which have inhibitory effect on one or more protein kinases that are involved in cell mitosis.

Modulators Of Mitotic Kinases

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US Patent:
20100249067, Sep 30, 2010
Filed:
Jan 30, 2008
Appl. No.:
12/525174
Inventors:
Srinivas Rao Kasibhatla - San Diego CA, US
Kevin Hong - San Diego CA, US
Lin Zhang - San Diego CA, US
Marcus F. Boehm - San Diego CA, US
Junhua Fan - San Diego CA, US
Jean-Yves LeBrazidec - San Diego CA, US
Assignee:
Biogen Idec MA Inc. - Cambridge MA
International Classification:
A61K 31/519
C07D 487/04
C12N 9/99
C07D 413/14
A61K 31/5377
C07F 9/02
A61K 31/675
A61P 35/00
US Classification:
514 81, 544262, 5142621, 435184, 51425216, 544118, 5142342, 544244
Abstract:
The invention relates to compounds of Formula (I), a polymorph, an enantiomer, a stereoisomer, a solvate, an N-oxide derivative, or a pharmaceutically acceptable salt thereof: Formula (I), which have inhibitory effect on one or more protein kinases that are involved in cell mitosis.

Cxcr3 Receptor Agonists

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US Patent:
20190345133, Nov 14, 2019
Filed:
Aug 31, 2017
Appl. No.:
16/335641
Inventors:
- Couvet, CH
Philip Turnbull - San Diego CA, US
Lin Zhang - San Diego CA, US
Junhua Fan - San Diego CA, US
Junko Tamiya - San Diego CA, US
Marcos Steinberg - San Diego CA, US
Tom Fowler - Nottinghamshire, GB
Hanae Benelkebir - Nottinghamshire, GB
Raffaele Pasceri - Nottinghamshire, GB
Maria Ieva - Nottinghamshire, GB
Kevan Grant - Nottinghamshire, GB
Yang Tran - San Diego CA, US
International Classification:
C07D 401/06
C07D 217/26
C07D 401/12
C07D 401/14
C07D 405/12
Abstract:
Compounds are provided having the structure of the following Formula I: where R, R, R, Ra and Rare as defined herein. Pharmaceutical compositions comprising such compounds, as well as methods related to their manufacture and use, are also provided.
Control profile
Junhua Fan from San Diego, CA, age ~53 Get Report