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Julius Horoszewicz Phones & Addresses

  • Buffalo, NY
  • East Aurora, NY

Publications

Us Patents

Monoclonal Antibodies To A New Antigenic Marker In Epithelial Prostatic Cells And Serum Of Prostatic Cancer Patients

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US Patent:
51625040, Nov 10, 1992
Filed:
Jun 3, 1988
Appl. No.:
7/202869
Inventors:
Julius S. Horoszewicz - Williamsville NY
Assignee:
Cytogen Corporation - NJ
International Classification:
C07K 1528
C12N 520
C12P 2108
US Classification:
5303882
Abstract:
Monoclonal antibodies to prostatic cells, are produced by a hybridoma formed by fusing mouse lymphocytes and mouse myeloma cells. The monoclonal antibodies show specificity for a non-soluble, membrane associated, organ specific antigenic determinant limited in its distribution to normal and neoplastic, human prostate epithelial cells. The monoclonal antibodies, specifically 7E11-C5 monoclonal antibodies, may be suitable for diagnostic uses.

Methods Of Detecting Prostate Carcinoma Using A Monoclonal Antibody To A New Antigenic Marker In Epithelial Prostatic Cells Alone Or With A Monoclonal Antibody To An Antigen Of Lncap Cells

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US Patent:
57632022, Jun 9, 1998
Filed:
Jun 7, 1995
Appl. No.:
8/482515
Inventors:
Julius S. Horoszewicz - Williamsville NY
Assignee:
Cytogen Corporation - Princeton NJ
International Classification:
G01N 33574
C12P 2104
C12N 1500
C07K 1600
US Classification:
435 723
Abstract:
Monoclonal antibodies to prostatic cells, are produced by a hybridoma formed by fusing mouse lymphocytes and mouse myeloma cells. The monoclonal antibodies show specificity for a non-soluble, membrane associated, organ specific antigenic determinant limited in its distribution to human prostate epithelial cells and normal prostatic epithelial cells. The monoclonal antibodies, specifically, 7Ell monoclonal antibodies, can be used diagnostically and therapeutically.

Hybridoma And Monoclonal Antibody 9H10-A4 Specific To An Antigen Of Lncap Cells

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US Patent:
55784844, Nov 26, 1996
Filed:
Sep 16, 1994
Appl. No.:
8/307544
Inventors:
Julius S. Horoszewicz - Williamsville NY
Assignee:
Cytogen Corporation - Princeton NJ
International Classification:
C12N 1520
C07K 1618
US Classification:
43524027
Abstract:
Monoclonal antibodies, specifically 9H10-A4 monoclonal antibodies, specific to an epitope present on the surface of LNCaP cells, are produced by hybridoma cell line 9H10-A4 formed by fusing mouse lymphocytes and mouse myeloma cells. 9H10-A4 monoclonal antibodies are useful to positively identify LNCaP cells and distinguish them from other cultured cells, and as a reliable control in competitive binding studies for detection of circulating antigens associated with prostate carcinoma.
Julius S Horoszewicz from Buffalo, NYDeceased Get Report