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Hua C Ooi

from Mill Creek, WA
Age ~50
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Also known as:
Hua Chee Ooi, Hau C Ooi, Ooi Hua, Ooi Huache, E Chee Ooi, E Ooi, Hua I, Ooi E
Phone and address:
15432 34Th Ave SE, Bothell, WA 98012
(425) 337-2626
Connected to:
Amy Ooi, 53Boon C Ooi, 70Chew S Ooi, 60Ching T Ooi, 56Chong W Ooi, 45Joo T Ooi, 49Oon C Ooi, 55Richard Y Ooi, 34See J Ooi, 53Tomas C Ooka, 62

Hua Ooi Phones & Addresses

  • 15432 34Th Ave SE, Bothell, WA 98012 (425) 337-2626
  • Mill Creek, WA
  • Issaquah, WA
  • 11905 93Rd Ave, Kirkland, WA 98034 (425) 821-6458
  • 11905 93Rd Ave NE #104, Kirkland, WA 98034 (425) 337-2626
  • La Jolla, CA
  • Gainesville, FL
  • Snohomish, WA
  • Kiona, WA
  • San Diego, CA
  • Orlando, FL

Publications

Us Patents

Quinazolinones As Inhibitors Of Human Phosphatidylinositol 3-Kinase Delta

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US Patent:
RE44599, Nov 12, 2013
Filed:
Dec 28, 2012
Appl. No.:
13/730276
Inventors:
Danwen Huang - Sammamish WA, US
Edward A. Kesicki - Bothell WA, US
Hua Chee Ooi - Kirkland WA, US
Amy Oliver - Bothell WA, US
Fuqiang Ruan - Bellevue WA, US
Jennifer Treiberg - Redmond WA, US
Kamal Deep Puri - Lynnwood WA, US
Assignee:
ICOS Corporation - Indianapolis IN
International Classification:
A01N 43/54
A01N 43/00
C07D 473/00
C07D 239/72
US Classification:
514183, 5142661, 544277, 544287
Abstract:
Compounds that inhibit P13Kδ activity, including compounds that selectively inhibit P13Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (P13Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which P13Kδ plays a role in leukocyte function, using the compounds also are disclosed.

6-Fluoro-3-Phenyl-2-[1-(9H-Purin-6-Ylamino)Ethyl]-3H-Quinazolin-4-One As An Inhibitor Of Human Phosphatidylinositol 3-Kinase Delta

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US Patent:
8586597, Nov 19, 2013
Filed:
Dec 27, 2012
Appl. No.:
13/728807
Inventors:
Danwen Huang - Sammamish WA, US
Edward A. Kesicki - Bothell WA, US
Hua Chee Ooi - Kirkland WA, US
Amy Oliver - Bothell WA, US
Fuqiang Ruan - Bellevue WA, US
Jennifer Treiberg - Redmond WA, US
Kamal Deep Puri - Lynnwood WA, US
Assignee:
ICOS Corporation - Indianapolis IN
International Classification:
A61K 31/517
US Classification:
5142661, 5142663, 544277, 544287
Abstract:
Compounds that inhibit PI3Kδ activity, including compounds that selectively inhibit PI3Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform PI3Kδ activity, and methods of treating diseases, such as disorders of immunity and inflammation in which PI3Kδ plays a role in leukocyte function, using the compounds also are disclosed. An exemplary compound disclosed in this application is shown below.

Quinazolinones As Inhibitors Of Human Phosphatidylinositol 3-Kinase Delta

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US Patent:
RE44638, Dec 10, 2013
Filed:
Dec 28, 2012
Appl. No.:
13/730256
Inventors:
Kerry W. Fowler - Seattle WA, US
Danwen Huang - Sammamish WA, US
Edward A. Kesicki - Bothell WA, US
Hua Chee Ooi - Kirkland WA, US
Amy Oliver - Bothell WA, US
Fuqiang Ruan - Bellevue WA, US
Jennifer Treiberg - Redmond WA, US
Kamal Deep Puri - Lynnwood WA, US
Assignee:
ICOS Corporation - Indianapolis IN
International Classification:
A61K 31/517
US Classification:
5142661, 544277, 544287
Abstract:
The invention provides a class of substituted quinazolinone compounds and methods of treating diseases mediated by PI3Kδ activity. The disclosed compounds are useful in treating diseases such as bone-resorption disorders; and cancer, especially hematopoietic cancers, lymphomas, multiple myelomas and leukemia. The compounds are also useful in disrupting or inhibiting cellular processes such as leukocyte function or accumulation, neutrophils function, lymphocyte proliferation, and endogenous immune responses.

Quinazolinones As Inhibitors Of Human Phosphatidylinositol 3-Kinase Delta

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US Patent:
8207153, Jun 26, 2012
Filed:
Mar 25, 2010
Appl. No.:
12/732128
Inventors:
Kerry W. Fowler - Seattle WA, US
Danwen Huang - Sammamish WA, US
Edward A. Kesicki - Bothell WA, US
Hua Chee Ooi - Kirkland WA, US
Amy Oliver - Bothell WA, US
Fuqiang Ruan - Bellevue WA, US
Jennifer Treiberg - Redmond WA, US
Assignee:
ICOS Corporation - Bothell WA
International Classification:
A01N 43/54
A01N 43/00
C07D 473/00
C07D 239/72
US Classification:
514183, 5142661, 544277, 544287
Abstract:
Compounds that inhibit P13Kδ activity, including compounds that selectively inhibit P13Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (P13Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which P13Kδ plays a role in leukocyte function, using the compounds also are disclosed.

Quinazolinones As Inhibitors Of Human Phosphatidylinositol 3-Kinase Delta

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US Patent:
20080275067, Nov 6, 2008
Filed:
May 12, 2005
Appl. No.:
11/596092
Inventors:
Kerry W. Fowler - Seattle WA, US
Danwen Huang - Sammamish WA, US
Edward A. Kesicki - Bothell WA, US
Hua Chee Ooi - Kirkland WA, US
Amy R. Oliver - Bothell WA, US
Ruan Fuqiang - Bellevue WA, US
Jennifer Treiberg - Redmond WA, US
Assignee:
ICOS CORPORATION - Bothell WA
International Classification:
A61K 31/52
C07D 487/04
C12N 9/99
A61P 19/02
C12N 5/06
A61K 31/519
US Classification:
51426321, 544280, 544277, 5142651, 435184, 435375
Abstract:
Compounds that inhibit PI3Kδ activity, including compounds that selectively inhibit PI3Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which PI3Kδ plays a role in leukocyte function, using the compounds also are disclosed.

Heteroaryl Urea Derivatives Useful For Inhibiting Chk1

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US Patent:
20090143357, Jun 4, 2009
Filed:
Mar 29, 2006
Appl. No.:
11/908416
Inventors:
Frank Diaz - St. Petersburg FL, US
Francine S. Farouz - Mercer Island WA, US
Ryan Coatsworth Holcomb - Salt Lake City UT, US
Edward A. Kesicki - Bothell WA, US
Hua Chee Ooi - Kirkland WA, US
Alexander Rudolph - Snoqualmic WA, US
Frank Stappenbeck - San Diego CA, US
Eugene D. Thorsett - Half Moon Bay CA, US
John Joseph Gaudino - Longmont CO, US
Kimba Lee Fischer - Longmont CO, US
Adam Wade Cook - Broomfield CO, US
Assignee:
ICOS CORPORATION - Bothel WA
International Classification:
A61K 31/553
C07D 267/10
C07D 413/02
A61K 31/5377
C07D 241/02
A61K 31/496
C07D 417/02
A61K 31/541
A61P 35/00
US Classification:
51421115, 540544, 544120, 5142358, 544357, 51425211, 544 60, 5142278
Abstract:
Substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating cancer and other diseases characterized by defects in DNA replication, chromosome segregation, or cell division, also are disclosed.

Quinazolinones As Inhibitors Of Human Phosphatidylinositol 3-Kinase Delta

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US Patent:
20100256167, Oct 7, 2010
Filed:
Mar 25, 2010
Appl. No.:
12/732124
Inventors:
Kerry W. Fowler - Seattle WA, US
Danwen Huang - Sammamish WA, US
Edward A. Kesicki - Bothell WA, US
Hua Chee Ooi - Kirkland WA, US
Amy Oliver - Bothell WA, US
Fuqiang Ruan - Bellevue WA, US
Jennifer Treiberg - Redmond WA, US
International Classification:
A61K 31/52
C07D 473/32
A61P 35/00
A61P 35/02
US Classification:
51426321, 544277
Abstract:
Compounds that inhibit PI3Kδ activity, including compounds that selectively inhibit PI3Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which PI3Kδ plays a role in leukocyte function, using the compounds also are disclosed.

Quinazolinones As Inhibitors Of Human Phosphatidylinositol 3-Kinase Delta

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US Patent:
20120015964, Jan 19, 2012
Filed:
Jun 17, 2011
Appl. No.:
13/163597
Inventors:
Kerry W. Fowler - Seattle WA, US
Danwen Huang - Sammamish WA, US
Edward A. Kesicki - Bothell WA, US
Hua Chee Ooi - Kirkland WA, US
Amy Oliver - Bothell WA, US
Fuqiang Ruan - Bellevue WA, US
Jennifer Treiberg - Redmond WA, US
Assignee:
ICOS Corporation - Bothell WA
International Classification:
A61K 31/52
C12N 5/09
A61P 35/02
C07D 473/34
A61P 35/00
US Classification:
51426321, 544277, 435375
Abstract:
Compounds that inhibit PI3Kδ activity, including compounds that selectively inhibit PI3Kδ activity, are disclosed. Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3Kδ) activity, and methods of treating diseases, such as disorders of immunity and inflammation in which PI3Kδ plays a role in leukocyte function, using the compounds also are disclosed.
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Hua C Ooi from Mill Creek, WA, age ~50 Get Report