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Falguni Rupa Dasgupta

from Bozeman, MT
Age ~72

Falguni Dasgupta Phones & Addresses

  • 2491 Daws Dr, Bozeman, MT 59718 (406) 522-0631
  • Stamford, CT
  • 11 Pimentel Ct, Novato, CA 94949
  • 6 Laurel Ave, San Rafael, CA 94901 (415) 457-9955
  • Alameda, CA
  • Floral Park, NY
  • Darien, IL

Business Records

Name / Title
Company / Classification
Phones & Addresses
Falguni Dasgupta
Innovotech LLC
Noncommercial Research Organization
920 Technology Blvd, Bozeman, MT 59718

Publications

Us Patents

Biocompatible And Biodegradable Polymers From Renewable Natural Polyphenols

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US Patent:
8513374, Aug 20, 2013
Filed:
Sep 30, 2010
Appl. No.:
13/498886
Inventors:
Falguni Dasgupta - Bozeman MT, US
International Classification:
C08G 64/00
C08G 63/18
US Classification:
528195, 525277, 525453, 528 75, 528 85, 528196, 528204, 558268, 568316, 568646
Abstract:
This invention describes the use of resveratrol and curcumin, representatives of naturally occurring polyphenols, in their native form, after hydrogenation, and as their respective allyl derivatives, individually, in combination with themselves and other commercial monomers, to make representative varieties of polymers, e. g. , polycarbonates (PC), polyurethanes (PU), co-polymers and biodegradable polymers.

Combinatiorial Polymeric Compositions For Drug Delivery

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US Patent:
20120220749, Aug 30, 2012
Filed:
Feb 28, 2012
Appl. No.:
13/407388
Inventors:
Falguni DASGUPTA - Bozeman MT, US
International Classification:
C08G 75/28
US Classification:
528226, 528360
Abstract:
The present invention is directed towards the synthesis of polymeric drug delivery compositions which would address some of the important and difficult to realize aspects of polymer based drug delivery systems by being, biocompatible, stable, capable of achieving desired drug loading, and safe from accidental release while being non-toxic, easy to fabricate and safe for the environment.

Sialic Acid/Fucose Based Medicaments

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US Patent:
57505080, May 12, 1998
Filed:
Jun 16, 1993
Appl. No.:
8/078949
Inventors:
Falguni Dasgupta - Alameda CA
John Henry Musser - San Carlos CA
Assignee:
Glycomed Incorporated - Alameda CA
International Classification:
A61K 3170
C07H 1500
US Classification:
514 25
Abstract:
Compounds that are synthetically inexpensive to make relative to the naturally occurring selectin ligands and that retain selectin binding activity are described that have a three-dimensionally stable configuration for sialic acid and fucose, or analogs or derivatives of these groups, such that sialic acid and fucose are separated by a non-carbohydrate linker that permits binding between those groups and the selectins, such compounds being represented by the following general structure formula I(a): ##STR1## wherein m and n are independently an integer of from 1 to 5, Y and Z are independently a connecting moiety selected from the group consisting of --CH. sub. 2 --, --O--, --S--, --NR'and --NR'R"--(wherein R' and R" are independently H or an alkyl containing 1 to 4 carbon atoms); X is a connecting moiety which is selected from the group consisting of --O--, --S-- and --N--; and --R" may be --R'" or any moiety which does not interfere with the three-dimensional configuration of A or B so as to interfere with selectin binding and is preferably a moiety selected from the group consisting of --OR", --SR", --I, --N. sub. 3, and --NR'R", and A is selected from the group consisting of. alpha. and. beta. forms of sialic acid, Kemp's acid.

Substituted Lactose And Lactosamine Derivatives As Cell Adhesion Inhibitors

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US Patent:
55676839, Oct 22, 1996
Filed:
Jul 1, 1994
Appl. No.:
8/270874
Inventors:
Mina A. Nashed - Alexandria, EG
Falguni Dasgupta - Alameda CA
Saeed A. Abbas - Vallejo CA
John H. Musser - San Carlos CA
Darwin S. Asa - Galesburg MI
Assignee:
Glycomed Incorporated - Alameda CA
International Classification:
A61K 3170
A61K 31715
A61K 3700
A61K 3710
US Classification:
514 25
Abstract:
Simple lactose or lactosamine related compounds which behave as ligands for the ELAM-1 and related receptors are described. These compounds are useful in the treatment of conditions characterized by excess inflammation. These compounds are of the formula ##STR1## wherein each R. sup. 1 is independently H or lower alkyl (1-4C); R. sup. 2 is H, lower alkyl (1-4C), alkylaryl or one or more additional saccharide residues; R. sup. 3 and R. sup. 4 are each independently H, alkyl(1-6C), aryl or R. sup. 3 and R. sup. 4, taken together, form a five- or six-membered ring optionally containing a heteroatom selected from the group consisting of O, S, and NR. sup. 1 ; wherein said five- or six-membered ring may further be substituted by one or more substituents selected from the group consisting of (CHOR. sup. 1). sub. m H wherein m is 1-4, OR. sup. 1, OOCR. sup. 1, NR. sup. 1. sub. 2, NHCOR. sup. 1, and SR. sup. 1 ; Y is H, OR. sup. 1, OOCR. sup. 1, NR. sup. 1. sub. 2, NCOR. sup. 1 or SR. sup.

Sialic Acid/Fucose Based Assay Reagents And Assay Methods

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US Patent:
56609922, Aug 26, 1997
Filed:
Jun 5, 1995
Appl. No.:
8/464507
Inventors:
Falguni Dasgupta - Alameda CA
John Henry Musser - San Carlos CA
Assignee:
Glycomed Incorporated - Alameda CA
International Classification:
A61K 5100
G01N 3353
G01N 33567
A61M 3614
US Classification:
435 71
Abstract:
Compounds that are synthetically inexpensive to make relative to the naturally occurring selectin ligands and that retain selectin binding activity are described that have a three-dimensionally stable configuration for sialic acid and fucose, or analogs or derivatives of these groups, such that sialic acid and fucose are separated by a non-carbohydrate linker that permits binding between those groups and the selectins, such compounds being represented by the following general structural formula I(a): ##STR1## wherein m and n are independently an integer of from 1 to 5, Y and Z are independently a connecting moiety selected from the group consisting of --CH. sub. 2 --, --O--, --S--, --NR' and --NR'R"-- (wherein R' and R" are independently H or an alkyl containing 1 to 4 carbon atoms); X is a connecting moiety which is selected from the group consisting of --O--, --S--and --N--; and --R'" may be --R" or any moiety which does not interfere with the three-dimensional configuration of A or B so as to interfere with selectin binding and is preferably a moiety selected from the group consisting of --OR", --SR", --I, --N. sub. 3, and --NR'R" and A is selected from the group consisting of. alpha. and. beta. forms of sialic acid, Kemp's acid, Quinic acid, Glyceric acid, Lactic acid and acetic acid, and esters thereof and B is selected from the group consisting of. alpha. and. beta.

Sialic Acid/Fucose Based Medicaments

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US Patent:
56793219, Oct 21, 1997
Filed:
Jun 6, 1995
Appl. No.:
8/468788
Inventors:
Falguni Dasgupta - Alameda CA
John Henry Musser - San Carlos CA
Assignee:
Glycomed Incorporated - Alameda CA
International Classification:
A61K 4900
A61K 31715
G01N 3100
G01N 3348
US Classification:
424 91
Abstract:
Compounds that are synthetically inexpensive to make relative to the naturally occurring selectin ligands and that retain selectin binding activity are described that have a three-dimensionally stable configuration for sialic acid and fucose, or analogs or derivatives of these groups, such that sialic acid and fucose are separated by a non-carbohydrate linker that permits binding between those groups and the selectins, such compounds being represented by the following general structural formula I(a): ##STR1## wherein m and n are independently an integer of from 1 to 5, Y and Z are independently a connecting moiety selected from the group consisting of --CH. sub. 2 --, --O--, --S--, --NR' and --NR'R"-- (wherein R' and R" are independently H or an alkyl containing 1 to 4 carbon atoms); X is a connecting moiety which is selected from the group consisting of --O--, --S-- and --N--; and --R'" may be --R" or any moiety which does not interfere with the three-dimensional configuration of A or B so as to interfere with selectin binding and is preferably a moiety selected from the group consisting of --OR", --SR", --I, --N. sub. 3, and --NR'R", and A is selected from the group consisting of. alpha. and. beta. forms of sialic acid, Kemp's acid, Quinic acid, Glyceric acid, Lactic acid and acetic acid, and esters thereof and B is selected from the group consisting of. alpha. and. beta.

Synthesis Of Sialosides

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US Patent:
51380447, Aug 11, 1992
Filed:
Aug 13, 1990
Appl. No.:
7/566682
Inventors:
Falguni Dasgupta - Alameda CA
Assignee:
Glycomed, Inc. - Alameda CA
International Classification:
C07G 300
C07H 504
C07H 510
US Classification:
536 185
Abstract:
Reaction schemes for carrying out a variety of chemical synthesis are disclosed. The reactions produce. alpha. -(X)-sialosides wherein X is O, S, N or another compatible electron donating atom or molecular moiety. The reaction schemes include a relatively small number of steps to provide a yield with a relatively small amount of undesired. beta. -configuration product. Compounds synthesized are encompassed by the following general structural formula I. ##STR1## wherein R, R' and R" are each independently H, CH. sub. 3, acetyl, or a disaccharide which is preferably lactose.

Sialic Acid/Fucose Based Medicaments

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US Patent:
56588801, Aug 19, 1997
Filed:
Aug 12, 1994
Appl. No.:
8/289715
Inventors:
Falguni Dasgupta - San Leandro CA
John H. Musser - San Carlos CA
Daniel E. Levy - Oakland CA
Peng Cho Tang - Moraga CA
Assignee:
Glycomed Incorporated - Alameda CA
International Classification:
A61K 31715
A61K 3814
C07H 306
C07K 200
US Classification:
514 8
Abstract:
Compounds that exhibit selectin binding activity are described and have the following structural formula: ##STR1## where W is selected from a group including structures a-d below ##STR2## wherein p is an integer of from 0-2, q is an integer of from 0-3, and r is an integer of from 0-5; A is selected from the group consisting of. alpha. and. beta. forms of sialic acid, Kemp's acid, quinic acid, R and S forms of mandelic acid, R and S forms of glyceric acid, R and S forms of lactic acid, propionic and acetic acid, and esters and amides thereof, --SO. sub. 3, sulfonate, --PO. sub. 3, phosphonate, trifluoromethyl, diazine and triazine; B is selected from a group consisting of. alpha. and. beta. forms of fucose, arabinose and esters and substituted forms thereof wherein one or more of the OH groups is independently substituted with F, N. sub. 3, NHAc, NHCOCF. sub. 3.
Falguni Rupa Dasgupta from Bozeman, MT, age ~72 Get Report