Dipshikha Biswas

8283346, Oct 9, 2012

Nov 10, 2009

12/615903

A. K. Ganguly - Upper Montclair NJ, US
Dipshikha Biswas - Woodbridge NJ, US
Sesha Sridevi Alluri - Piscataway NJ, US
Danielle Caroccia - Hasbrouck Heights NJ, US
Chih-Hung Wang - New York NY, US
Eun Hee Kang - Fort Lee NJ, US

The Trustees of the Stevens Institute of Technology - Hoboken NJ

A61K 31/553
A61K 31/554
C07D 267/04
C07D 267/14

51421109, 514552

The described invention relates to novel human immunodeficiency virus protease inhibitors, pharmaceutical compositions containing at least one such inhibitor, methods of preparing such inhibitors, and methods of utilizing such inhibitors to treat HIV and HIV-related disorders.

20120040975, Feb 16, 2012

Apr 1, 2010

13/260950

Santhosh Francis Neelamkavil - Edison NJ, US
Bernard R. Neustadt - West Orange NJ, US
Andrew Stamford - Chatham Township NJ, US
Yan Xia - Edison NJ, US
Joel M. Harris - Blaine MN, US
Craig D. Boyle - Branchburg NJ, US
Samuel Chackalamannil - Califon NJ, US
Dipshikha Biswas - Woodbridge NJ, US
Hong Liu - Hillsborough NJ, US
Jinsong Hao - Belle Mead NJ, US
Claire M. Lankin - High Bridge NJ, US
Unmesh Shah - Green Brook NJ, US

A61K 31/537
C07D 401/12
C07D 491/08
A61P 3/00
A61K 31/506
C07D 487/08
A61P 3/10
A61P 3/04
C07D 451/06
C07D 498/08

5142305, 544319, 544105, 514269, 544230

The present invention relates to Bridged Bicyclic Heterocycle Derivatives, compositions comprising a Bridged Bicyclic Heterocycle Derivative, and methods of using the Bridged Bicyclic Heterocycle Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of a GPCR in a patient.

20120232073, Sep 13, 2012

Nov 16, 2010

13/508652

Santhosh Francis Neelamkavil - Edison NJ, US
Dipshikha Biswas - Woodbridge NJ, US
Samuel Chackalamannil - Califon NJ, US
Bernard R. Neustadt - West Orange NJ, US
Andrew Stamford - Chatham Township NJ, US
Hong Liu - Hillsborough NJ, US

A61K 31/519
C07D 498/04
C07D 473/28
A61P 3/00
A61K 31/5383
A61K 31/52
A61P 3/10
A61P 3/04
C07D 487/04
C07D 473/00

5142305, 544280, 544262, 544254, 544105, 544276, 544264, 5142651, 5142621, 5142611, 5142631

The present invention relates to Fused Bicyclic Pyrimidine Derivatives, compositions comprising a Fused Bicyclic Pyrimidine Derivative, and methods of using the Fused Bicyclic Pyrimidine Derivatives for treating or preventing obesity, diabetes, a metabolic disorder, a cardiovascular disease or a disorder related to the activity of a G-protein coupled receptor (GPCR) in a patient.

20160333021, Nov 17, 2016

Jan 16, 2015

15/110431

- Rahway NJ, US
Haifeng Tang - Metuchen NJ, US
Li Xiao - Cranbury NJ, US
Jing Su - Scotch Plains NJ, US
Guoqing Li - Belle Mead NJ, US
Shu-Wei Yang - Edison NJ, US
Weidong Pan - Hillsborough NJ, US
Haiqun Tang - Belle Mead NJ, US
Reynalda DeJesus - East Brunswick NJ, US
Jacqueline Hicks - Scotch Plains NJ, US
Matthew Lombardo - Flemington NJ, US
Hong Chu - Livingston NJ, US
William Hagmann - Westfield NJ, US
Alex Pasternak - Princeton NJ, US
Xin Gu - Scotch Plains NJ, US
Jinlong Jiang - Scotch Plains NJ, US
Shuzhi Dong - Plainsboro NJ, US
Clare London - Chatham NJ, US
Dipshikha Biswas - Woodbridge NJ, US
Katherine Young - Metuchen NJ, US
David N. Hunter - Scotch Plains NJ, US
Zhiqiang Zhao - Scotch Plains NJ, US
Dexi Yang - Livingston NJ, US

Merck Sharp & Dohme Corp. - Rahway NJ

C07D 491/048
A61K 31/41
A61K 45/06
A61K 31/407
A61K 31/197
C07D 405/12
A61K 31/5377
C07D 403/10
A61K 31/4192
A61K 31/496
C07D 401/10
A61K 31/454
A61K 31/4439
C07D 409/10
C07D 417/10
A61K 31/427
C07D 405/14
C07D 413/10
A61K 31/422
A61K 31/506
A61K 31/497
A61K 31/4178
A61K 31/501
A61K 31/4155
C07D 471/04
A61K 31/437
C07D 417/14
C07D 401/14
C07D 487/04
A61K 31/5025
A61K 31/4245
A61K 31/541
C07D 401/04
C07D 413/14
A61K 31/55
C07D 471/10
C07D 257/04

The present invention relates to compounds of formula (I) that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.

20160024091, Jan 28, 2016

Mar 10, 2014

14/774390

Alexander PASTERNAK - , US
Shuzhi DONG - , US
Haifeng TANG - , US
Jinlong JIANG - , US
Cangming YANG - , US
Dipshikha BISWAS - Woodbridge NJ, US
- Rahway NJ, US

MERCK SHARP & DOHME CORP. - Rahway NJ

C07D 471/10
A61K 31/444
A61K 31/506
A61K 31/435
A61K 31/5386
A61K 31/501
C07D 471/20
A61K 31/4995
C07D 498/20
A61K 45/06
A61K 31/497

The present invention provides compounds of Formula Iand the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.