US Patent:
20060271062, Nov 30, 2006
Inventors:
Paul Kaufman - Madison WI, US
Baohe Tian - Madison WI, US
International Classification:
A61F 9/013
US Classification:
606107000, 623006560, 514912000
Abstract:
It is disclosed here that actin-disrupting compounds and 1-(5-isoquinolinyl-sulfonyl)-2-methylpiperazine can be used to facilitate the removal of lens epithelial cells from the lens capsule during cataract surgery and they may also be used to inhibit lens epithelial cells' proliferation and/or migration after surgery to reduce the risk or severity of posterior capsular opacification. Various related methods, kits, and ocular implants for reducing the risk or severity of posterior capsular opacification are provided.