Inventors:
Michelle Akerman - San Francisco CA, US
Jonathan Houze - San Mateo CA, US
Daniel C. H. Lin - Redwood City CA, US
Jinqian Liu - Palo Alto CA, US
Jiwen Liu - Foster City CA, US
Jian Luo - Brisbane CA, US
Zhihua Ma - San Mateo CA, US
Julio C. Medina - San Carlos CA, US
Wei Qiu - Foster City CA, US
Jeffrey D. Reagan - Millbree CA, US
Rajiv Sharma - Fremont CA, US
Michael J. Schmitt - San Francisco CA, US
Stephen J. Shuttleworth - Bourne End, GB
Ying Sun - Albany CA, US
Yingcai Wang - Fremont CA, US
Jian Zhang - Foster City CA, US
Liusheng Zhu - Burlingame CA, US
Assignee:
Amgen Inc. - Thousand Oaks CA
International Classification:
C07C 59/40
C07C 65/03
Abstract:
The present invention provides compounds useful, for example, for modulating insulin levels in a subject and that have the general formulaQ—L—P—L—M—X—L—Awherein the definitions of the variables Q, L, P, L, M, X, Land A are provided herein. The present invention also provides compositions and methods for use of the compounds, for instance, for treatment of type II diabetes.
