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Yuelian M Xu

from East Haven, CT
Age ~58
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Related to:
Haitao Xu, 53Boyang Xu
Connected to:
Alexander A Xu, 33Anqi Xu, 34Benjamin B Xu, 67Bonnie Xu, 37Bonny J Xu, 32Boris Xu, 33Changhai Xu, 54Charline Q Xu, 63Chengyuan Xu, 45Chris X Xu, 60

Yuelian Xu Phones & Addresses

  • 48 Highland Ave, New Haven, CT 06513 (203) 467-2125
  • 140 Mill St, East Haven, CT 06512 (203) 467-2125
  • 1307 6Th St, Gainesville, FL 32601
  • 381 Maguire Vlg, Gainesville, FL 32603
  • Newington, CT
  • 300 Candlewyck Dr, Kalamazoo, MI 49001 (269) 342-0722
  • Branford, CT
  • Wallingford, CT

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Business Records

Name / Title
Company / Classification
Phones & Addresses
Yuelian Xu
Principal
Chinglu Pharmaceutical Research LLC
Nonclassifiable Establishments
48 Highland Ave, New Haven, CT 06513

Publications

Us Patents

Imidazol-1-Ylmethyl Pyridazine Derivatives

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US Patent:
7122546, Oct 17, 2006
Filed:
Oct 7, 2003
Appl. No.:
10/680351
Inventors:
Linghong Xie - Guilford CT, US
Bingsong Han - Hamden CT, US
Yuelian Xu - East Haven CT, US
George D. Maynard - Clinton CT, US
Assignee:
Neurogen Corporation - Branford CT
International Classification:
C07D 403/06
C07D 403/14
A61K 31/501
A61P 25/22
A61P 25/24
US Classification:
5142365, 51425202, 51425203, 544114, 544121, 544122, 544238
Abstract:
The invention provides imidazol-1-ylmethyl pyridazine derivatives of the formula:.

Imidazo-Pyrimidines And Triazolo-Pyrimidines: Benzodiazepine Receptor Ligands

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US Patent:
7271170, Sep 18, 2007
Filed:
Jul 23, 2004
Appl. No.:
10/898690
Inventors:
Linghong Xie - Guilford CT, US
Bingsong Han - North Haven CT, US
Yuelian Xu - East Haven CT, US
George Maynard - Clinton CT, US
Bertrand L. Chenard - Waterford CT, US
Kenneth Shaw - Weston CT, US
Yang Gao - Branford CT, US
Assignee:
Neurogen Corporation - Branford CT
International Classification:
C07D 487/04
A61K 31/519
A61P 25/24
A61P 25/22
A61P 25/20
US Classification:
5142591, 51425931, 5142593, 544263, 544281, 544282
Abstract:
Compounds of Formula I.

Aryl Acid Pyrimidinyl Methyl Amides, Pyridazinyl Methyl Amides And Related Compounds

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US Patent:
7351826, Apr 1, 2008
Filed:
Feb 16, 2004
Appl. No.:
10/544882
Inventors:
Linghong Xie - Guilford CT, US
Bingsong Han - North Haven CT, US
Yuelian Xu - East Haven CT, US
Assignee:
Neurogen Corporation - Branford CT
International Classification:
C07D 487/00
A61K 31/519
US Classification:
544263, 5142591, 5142593, 51425931, 514923, 544224, 544236, 544242, 544255, 544256, 544262, 544281, 546 1, 546255, 5462681, 546290
Abstract:
The invention provides compounds of Formula (I) that bind to GABAreceptors. In the above formula, variables are defined herein. Such compounds may be used to modulate ligand binding to GABAreceptors in vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) disorders in humans, domesticated companion animals, and livestock animals. Compounds provided herein may be administered alone or in combination with one or more other CNS agents to potentiate the effects of the other CNS agent(s). Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting GABAreceptors (e. g. , receptor localization studies).

Dipiperazinyl Ketones And Related Analogues

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US Patent:
7851474, Dec 14, 2010
Filed:
Jul 28, 2006
Appl. No.:
11/495986
Inventors:
Linghong Xie - Guilford CT, US
Joseph W. Ochterski - Middlefield CT, US
Yang Gao - Madison CT, US
Bingsong Han - North Haven CT, US
Timothy M. Caldwell - Guilford CT, US
Yuelian Xu - East Haven CT, US
John M. Peterson - Durham CT, US
Ping Ge - Durham CT, US
Robert Ohliger - Deep River CT, US
Assignee:
Neurogen Corporation - Branford CT
International Classification:
A61K 31/497
C07D 241/04
C07D 295/00
US Classification:
51425212, 544358
Abstract:
Dipiperazinyl ketones and related analogues are provided, as are methods for their preparation and use. Such compounds may generally be used to modulate ligand binding to histamine H3 receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of disorders in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and therapeutic methods are provided, as are methods for using such ligands for detecting histamine H3 receptors (e. g. , receptor localization studies).

4-Imidazol-1-Ylmethyl Pyrimidine Derivatives

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US Patent:
20040102457, May 27, 2004
Filed:
Nov 6, 2003
Appl. No.:
10/702629
Inventors:
Linghong Xie - Guilford CT, US
Bingsong Han - Hamden CT, US
Yuelian Xu - East Haven CT, US
George Maynard - Clinton CT, US
Assignee:
Neurogen Corporation, A Corporation of the State of Delaware - Branford CT
International Classification:
A61K031/506
C 07D 4 3/02
US Classification:
514/256000, 514/269000, 544/333000, 544/331000, 544/317000
Abstract:
The invention provides 4-imidazol-1-ylmethyl pyrimidine of the formula that bind to GABAreceptors. In the above formula, R, RR, R, R, Rand Ar are defined herein. Such compounds may be used to modulate ligand binding to GABAreceptors in vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) disorders in humans, domesticated companion animals, and livestock animals. Compounds provided herein may be administered alone or in combination with one or more other CNS agents to potentiate the effects of the other CNS agent(s). Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting GABAreceptors (e.g., receptor localization studies).

Neurokinin-3 Receptor Modulators: Diaryl Imidazole Derivatives

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US Patent:
20050148601, Jul 7, 2005
Filed:
Dec 7, 2004
Appl. No.:
11/007652
Inventors:
George Maynard - Clinton CT, US
Stanislaw Rachwal - Irvine CA, US
Wallace Pringle - Guilford CT, US
Jun Yuan - Guilford CT, US
Linghong Xie - Guilford CT, US
Yuelian Xu - East Haven CT, US
Bingsong Han - North Haven CT, US
International Classification:
A61K031/538
A61K031/506
A61K031/498
A61K031/4439
A61K031/427
A61K031/4178
C07D043/02
C07D413/02
C07D417/02
US Classification:
514256000, 514341000, 514365000, 514397000, 514400000, 544331000, 546272700, 548200000, 548311100, 548338100, 544353000, 514230500, 514249000, 544105000
Abstract:
The invention relates to compounds of general Formula I: wherein the variables are as defined herein. Also provided are pharmaceutical compositions comprising such compounds, and methods for treating patients suffering from a disorder responsive to neurokinin-3 receptor modulation. NK-3 receptor modulators provided herein are also useful as probes for the localization of NK-3 receptors.

Substituted Imidazolopyrazine And Triazolopyrazine Derivatives: Gabaa Receptor Ligands

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US Patent:
20060247245, Nov 2, 2006
Filed:
May 3, 2004
Appl. No.:
10/554153
Inventors:
Yuelian Xu - East Haven CT, US
International Classification:
A61K 31/498
C07D 487/04
US Classification:
514249000, 544349000
Abstract:
Compounds of Formula (1) are provided, as are methods for their preparation. The variables Z, Z, Z, R, R, R, R, R, and Ar in the above Formula are defined herein. Such compounds may be used to modulate ligand binding to GABAreceptors in vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) disorders in humans, domesticated companion animals, and livestock animals. Compounds provided herein may be administered alone or in combination with one or more other CNS agents to potentiate the effects of the other CNS agent(s). Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting GABAreceptors (e.g., receptor localization studies).

Piperazinyl Oxoalkyl Tetrahydroisoquinolines And Related Analogues

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US Patent:
20070232591, Oct 4, 2007
Filed:
Mar 8, 2007
Appl. No.:
11/716354
Inventors:
Yang Gao - Madison CT, US
Bingsong Han - North Haven CT, US
Yuelian Xu - East Haven CT, US
Timothy Caldwell - Guilford CT, US
Linghong Xie - Guilford CT, US
International Classification:
A61K 31/55
A61K 31/496
A61K 31/4709
C07D 403/02
US Classification:
514217010, 514253040, 514253050, 544362000, 544363000, 514307000, 546146000, 540594000
Abstract:
Piperazinyl oxoalkyl tetrahydroisoquinolines and related analogues of the Formula: are provided, in which variables are as described herein. Such compounds may be used to modulate ligand binding to histamine H3 receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of central nervous system (CNS) and other disorders in humans, domesticated companion animals and livestock animals. Compounds provided herein may be administered alone or in combination with one or more other CNS agents to potentiate the effects of the other CNS agent(s). Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such ligands for detecting histamine H3 receptors (e.g., receptor localization studies).
Control profile
Yuelian M Xu from East Haven, CT, age ~58 Get Report