Yong Hoon Choi

6627211, Sep 30, 2003

Jul 24, 2000

09/624305

Yong Moon Choi - Towaco NJ
Lianli Li - Fresh Meadows NY
Kwon H. Kim - Bridgewater NJ

SK Corporation

A61F 1300

424434, 424 45, 514 78, 514975

A method of vehicle modulated administration of an anticonvulsive agent to the nasal mucous membranes of humans and animals is disclosed. The vehicle system is an aqueous pharmaceutical carrier comprising an aliphatic alcohol, a glycol and a biological surfactant such as a bile salt or a lecithin. The pharmaceutical composition provides a means to control and promote the rate and extent of transmucosal permeation and absorption of the medicaments via a single and multiple administration. Nasal administration of the pharmaceutical preparation produces a high plasma concentration of the anticonvulsant nearly as fast as intravenous administration. Such compositions are particularly suitable for a prompt and timely medication of patients in the acute and/or emergency treatment of status epilepticus and other fever-induced seizures.

7132112, Nov 7, 2006

Aug 5, 2003

10/634689

Yong Moon Choi - Towaco NJ, US
Lianli Li - Fresh Meadows NY, US
Kwon H. Kim - Bridgewater NJ, US

SK Corporation

A61F 13/00
A61L 9/04

424434, 424 45

A novel method of vehicle modulated administration of an anticonvulsive agent to the mucous membranes of humans and animals is disclosed. The vehicle system is an aqueous pharmaceutical carrier comprising an aliphatic alcohol (10–80%) or a glycol (10–80%), and their combinations with a biological surfactant such as a bile salt or a lecithin. The pharmaceutical composition provides a means to control and promote the rate and extent of transmucosal permeation and absorption of the medicaments via a single and multiple administration. Nasal administration of the pharmaceutical preparation produces a high plasma concentration of the anticonvulsant nearly as fast as intravenous administration. Such compositions are particularly suitable for a prompt and timely medication of patients in the acute and/or emergency treatment of status epilepticus and other fever-induced seizures.

7446127, Nov 4, 2008

Aug 26, 2004

10/926615

Yong Moon Choi - Pine Brook NJ, US
Hunwoo Shin - Livingston NJ, US
Palanichamy Ilankumaran - Pinerbrook NJ, US
Hong Wook Kim - Lincoln Park NJ, US

SK Holdings Co, Ltd. - Seoul

A01N 43/16
C07D 263/30

514458, 548235

There are disclosed derivatives of 3-chromancarboxylic acid represented by formula I.

7456293, Nov 25, 2008

Mar 28, 2006

11/391031

Yong Moon Choi - Pinebrook NJ, US
Hunwoo Shin - Livingston NJ, US
Palanichamy Ilankumaran - Pinebrook NJ, US

SK Holding Co., Ltd - Seoul

A61K 31/4184
C07D 235/04

5483101, 514394

The present invention is concerned with racemic or enantiomerically enriched substituted carboxylic acids and derivatives thereof represented by Formula 1;.

7598279, Oct 6, 2009

Apr 20, 2006

11/407526

Yong Moon Choi - Pinebrook NJ, US
Choon-Gil Kim - Daejon, KR
Han-Ju Yi - Daejeon, KR
Young-Sun Kang - Daejeon, KR
Hyun-Seok Lee - Daejeon, KR

SK Holdings Co., Ltd. - Seoul

A61K 31/445
C07D 401/12
C07D 249/08
C07D 249/04

514359, 514281, 514283, 548250, 548255, 5482622

Azole compounds containing carbamoyl group and pharmaceutically useful salts thereof are described. The compounds are effective anticonvulsants which are used in the treatment of disorders of the central nervous system, especially as anxiety, depression, convulsion, epilepsy, migraine, bipolar disorder, drug abuse, smoking, ADHD, obesity, sleep disorder, neuropathic pain, stroke, cognitive impairment, neurodegeneration, stroke and muscle spasm.

20010034365, Oct 25, 2001

Jan 31, 2001

09/774736

Yong Choi - Towaco NJ, US
Min Kim - Montvale NJ, US
Jeonghan Park - Flanders NJ, US

C07C271/08
A61K031/27

514/483000, 560/026000

Enantiomeric forms of monocarbamates of halogenated 2-pheny-1,2 -ethanediol and dicarbamates of halogenated 2-pheny-1,2-ethanediol have been found to be effective in the treatment of disorders of the central nervous system, especially as anti-convulsive or anti-epileptic agents.

20050002987, Jan 6, 2005

Jun 16, 2004

10/869195

Yong Moon Choi - Pine Brook NJ, US
Kwon Kim - Palisades Park NJ, US

A61K009/70
A61K009/14

424434000, 424489000

Diazepam is administered intranasally in the form of specific microemulsions having advantageous properties. The microemulsions are comprised of about equal quantities of a fatty acid and water with the remainder being a hydrophilic surfactant, a polar solvent and an alcohol in a weight ratio such that alcohol is present in a greater quantity by weight than either of the other two. Nasal administration of the subject microemulsions produces a high plasma concentration of diazepam nearly as fast as intravenous administration. The present microemulsions are particularly suitable for a prompt and timely treatment of patients in the acute and/or emergency treatment of status epilepticus and other fever-induced seizures.

20060058548, Mar 16, 2006

Nov 3, 2005

11/266555

Yong Choi - Pine Brook NJ, US
Min Kim - Montville NJ, US

C07D 217/12

560157000, 546146000

A process for preparing O-carbamoyl aminoalcohols represented by Formula I wherein: n is an integer from 0 and 5;