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William M Volcheck

from Lincoln, NE
Age ~53
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Also known as:
Bill M Volcheck, Bil Volcheck, Tina Volcheck
Phone and address:
7310 Greenwood Ct, Lincoln, NE 68507
(402) 432-2665
Related to:
Anna A MarshallPatricia Marshall, 72Andrea Gruber, 44Dona Marotta, 71
Connected to:
John M Volcheck, 59Nicole A Volchko, 46Larry L Volcik, 75Lindsey Volcik, 40Michael R Volcik, 55Alourde Volcimus, 67Carole A Volcjak, 85Ilse R Volckaert, 94Kevin M Volckaert, 58Thomas Volckaert, 37

William Volcheck Phones & Addresses

  • 7310 Greenwood Ct, Lincoln, NE 68507 (402) 432-2665
  • 6100 Vine St, Lincoln, NE 68505 (402) 325-9135
  • 75 Hinesburg Rd, South Burlington, VT 05403
  • Omaha, NE
  • 7310 Greenwood Ct, Lincoln, NE 68507

Work

Position: Farming-Forestry Occupation

Education

Degree: High school graduate or higher

Emails

w***[email protected]

Publications

Us Patents

Cyanine Dyes And Methods Of Use

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US Patent:
8227621, Jul 24, 2012
Filed:
Jun 12, 2006
Appl. No.:
11/423675
Inventors:
Xinzhan Peng - Lincoln NE, US
Xinshe Xu - Lincoln NE, US
Daniel R. Draney - Lincoln NE, US
Garrick M. Little - Lincoln NE, US
Jiyan Chen - Lincoln NE, US
William M. Volcheck - Lincoln NE, US
Charles Prescott - Lincoln NE, US
Assignee:
Li-Cor, Inc. - Lincoln NE
International Classification:
C07D 209/56
A61B 5/00
US Classification:
548427, 424 96
Abstract:
The present invention provides for cyanine dyes as near IR quenchers. The cyanine dyes have absorption wavelengths in the near-infrared region of about 650-900 nm and are essentially non-fluorescent. The dyes of the invention have at least one linking group. The present invention also provides substantially non-fluorescent, NIR probes. Biological assays based on these novel, substantially non-fluorescent, NIR probes are also provided.

Optical Fluorescent Imaging

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US Patent:
20060280688, Dec 14, 2006
Filed:
May 19, 2006
Appl. No.:
11/419457
Inventors:
Joy Kovar - Lincoln NE, US
Jiyan Chen - Lincoln NE, US
Daniel Draney - Lincoln NE, US
D. Olive - Lincoln NE, US
William Volcheck - Lincoln NE, US
Xinshe Xu - Lincoln NE, US
Ananda Lugade - Austin TX, US
Narasimhachari Narayanan - Westford MA, US
Assignee:
LI-COR, Inc. - Lincoln NE
International Classification:
A61K 49/00
C07K 14/52
C07K 14/54
C07K 14/56
C07K 14/575
C07K 14/745
C07K 16/46
C08B 37/10
C08B 37/00
C08B 30/18
C07D 403/02
C07D 403/14
C12N 9/64
US Classification:
424009600, 530409000, 530351000, 530391100, 530399000, 536021000, 548455000, 536054000, 536046000, 546200000, 530383000, 435226000
Abstract:
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared (NIR) spectral range. The NIR is highly sensitive for tumor detection and tracking. The application discloses targeting a tumor-enriched cell surface receptor with a ligand-conjugated fluorescent probe, which specifically allows detection of the tumor relative to the negligible animal autofluorescence.

Optical Fluorescent Imaging

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US Patent:
20120258048, Oct 11, 2012
Filed:
Jun 15, 2012
Appl. No.:
13/525136
Inventors:
Joy Kovar - Lincoln NE, US
Jiyan Chen - Lincoln NE, US
Daniel R. Draney - Lincoln NE, US
D. Michael Olive - Lincoln NE, US
William M. Volcheck - Lincoln NE, US
Xinshe Xu - Lincoln NE, US
Ananda G. Lugade - Austin TX, US
Narasimhachari Narayanan - Westford MA, US
Assignee:
LI-COR, INC. - Lincoln NE
International Classification:
C07D 209/14
C07D 209/60
A61K 49/00
US Classification:
424 96, 548455, 548427
Abstract:
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared (NIR) spectral range. The NIR is highly sensitive for tumor detection and tracking. The application discloses targeting a tumor-enriched cell surface receptor with a ligand-conjugated fluorescent probe, which specifically allows detection of the tumor relative to the negligible animal autofluorescence.

Optical Fluorescent Imaging In Histology

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US Patent:
20130052637, Feb 28, 2013
Filed:
Aug 29, 2012
Appl. No.:
13/598583
Inventors:
Joy Kovar - Lincoln NE, US
Jiyan Chen - Lincoln NE, US
Daniel R. Draney - Lincoln NE, US
D. Michael Olive - Lincoln NE, US
William M. Volcheck - Lincoln NE, US
Xinshe Xu - Lincoln NE, US
Ananda G. Lugade - Austin TX, US
Narasimhachari Narayanan - Westford MA, US
Assignee:
LI-COR, INC. - Lincoln NE
International Classification:
G01N 21/75
G01N 21/64
US Classification:
435 5, 436501, 435 72, 435 723, 435 732
Abstract:
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared (NIR) spectral range. The NIR is highly sensitive for tumor detection and tracking. The application discloses targeting a tumor-enriched cell surface receptor with a ligand-conjugated fluorescent probe, which specifically allows detection of the tumor relative to the negligible animal autofluorescence.

Fluorescent Imaging With Substituted Cyanine Dyes

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US Patent:
20130280172, Oct 24, 2013
Filed:
Mar 15, 2013
Appl. No.:
13/836202
Inventors:
Daniel R. Draney - Lincoln NE, US
Mark Cradduck - Lincoln NE, US
Lael Cheung - Lincoln NE, US
Kousik Kundu - Lincoln NE, US
William M. Volcheck - Lincoln NE, US
International Classification:
A61K 49/00
US Classification:
424 96, 548455, 5303915, 530350, 530331, 530317, 540587, 540578, 546113, 548427, 540476, 435 34
Abstract:
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula I are presented:Also included are bioconjugates of the compounds of Formula I, methods of labeling biomolecules with the compounds, and methods of imaging.

Ir Dyes For Fluorescence Imaging

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US Patent:
20200085976, Mar 19, 2020
Filed:
Nov 18, 2019
Appl. No.:
16/687450
Inventors:
- Lincoln NE, US
William M. Volcheck - Lincoln NE, US
Katie Schaepe - Lincoln NE, US
Vassil Elitzin - Lincoln NE, US
Joy Kovar - Lincoln NE, US
Assignee:
LI-COR, INC. - Lincoln NE
International Classification:
A61K 49/00
A61B 5/20
A61B 5/00
C09B 23/10
C09B 23/08
C09B 23/01
Abstract:
A method for organ imaging, comprising: administering to a subject a diagnostic effective amount of 2-((E)-2-((E)-3-(2-((E)-3,3-dimethyl-5-sulfonato-1-(4-sulfonatobutyl)indolin-2-ylidene)ethylidene)-2-phenoxycyclohex-1-en-1-yl)vinyl)-3,3-dimethyl-1-(4-sulfonatobutyl)-3H-indol-1-ium-5-sulfonate or 2-((E)-2-((E)-3-(2-((E)-3,3-dimethyl-5-sulfonato-1-(4-sulfonatobutyl)indolin-2-ylidene)ethylidene)-2-(4-sulfonatophenoxy)cyclohex-1-en-1-yl)vinyl)-3,3-dimethyl-1-(4-sulfonatobutyl)-3H-indol-1-ium-5-sulfonate. In one embodiment, the organ includes one or more of kidney, bladder, liver, gall bladder, spleen, intestine, heart, lungs and muscle.

Ir Dyes For Fluorescence Imaging

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US Patent:
20200078474, Mar 12, 2020
Filed:
Nov 18, 2019
Appl. No.:
16/687479
Inventors:
- Lincoln NE, US
William M. Volcheck - Lincoln NE, US
Katie Schaepe - Lincoln NE, US
Vassil Elitzin - Lincoln NE, US
Assignee:
LI-COR, INC. - Lincoln NE
International Classification:
A61K 49/00
A61B 5/20
A61B 5/00
C09B 23/10
C09B 23/08
C09B 23/01
Abstract:
A composition comprising: a polymorphic form of 2-((E)-2-((E)-3-(2-((E)-3,3-dimethyl-5-sulfonato-1-(4-sulfonatobutyl)indolin-2-ylidene)ethylidene)-2-phenoxycyclohex-1-en-1-yl)vinyl)-3,3-dimethyl-1-(4-ulfonatobutyl)-3H-indol- 1- ium-5-sulfonate or 2-((E)-2-((E)-3-(2-((E)-3,3-dimethyl-5-sulfonato-1-(4-sulfonatobutyl)indolin-2-ylidene)ethylidene)-2-(4-sulfonatophenoxy)cyclohex-1-en-1-yl)vinyl)-3,3-dimethyl-1-(4-sulfonatobutyl)-3H-indol-1-ium-5-sulfonate and an acceptable excipient.

Solid Cyanine Dyes

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US Patent:
20180296704, Oct 18, 2018
Filed:
Apr 12, 2018
Appl. No.:
15/951911
Inventors:
- Lincoln NE, US
William M. Volcheck - Lincoln NE, US
Katie Schaepe - Lincoln NE, US
Rahul Patil - Lincoln NE, US
Assignee:
LI-COR, Inc. - Lincoln NE
International Classification:
A61K 49/00
C09B 23/01
A61B 5/00
A61B 5/20
A61M 5/00
Abstract:
Polymorphs of Formula I, which is 2-((E)-2-((E)-3-(2-((E)-3,3-dimethyl-5-sulfonato-1-(4-sulfonatobutyl)indolin-2-ylidene)ethylidene)-2-phenoxycyclohex-1-en-1-yl)vinyl)-3,3-dimethyl-1-(4-sulfonatobutyl)-3H-indol-1-ium-5-sulfonate and methods of making are provided.A method for organ imaging, comprising administering to a subject, a diagnostic effective amount of a composition comprising a polymorph of Formula I are also provided. In one embodiment, the organ includes one or more of kidney, bladder, ureter, urethra, bile ducts, liver, and gall bladder.
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William M Volcheck from Lincoln, NE, age ~53 Get Report