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William F Beschorner

from Omaha, NE
Age ~48
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Also known as:
William E Beschorner, William R
Phone and address:
2614 161St Ave, Omaha, NE 68116
Related to:
Jessica C Mckenzie, 42Kathleen WardThomas Nicholas, 92Tiffany Vitkofsky, 44Joel Mcclosky, 46
Connected to:
Doris J Beschorner, 87Kaytie J Beschorner, 33William Besco, 46Sharon M Bescoe, 72Rhonda B Bescript, 59Cheryl L Besden, 73Ashlie R Besecker, 33Christophe P Besecker, 64Logan Besecker, 31Andrea M Beseda, 33

William Beschorner Phones & Addresses

  • 2614 161St Ave, Omaha, NE 68116
  • Cary, NC
  • Baldwin, MD

Professional Records

License Records

William Edward Beschorner Md

License #:
20713 - Expired
Category:
Medicine
Issued Date:
Jan 29, 1998
Effective Date:
Oct 5, 2012
Expiration Date:
Oct 1, 2012
Type:
Physician

Medicine Doctors

William Beschorner Photo 1

William Edward Beschorner

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Specialties:
Allergy & Immunology
Pathology
Anatomic Pathology
Anatomic Pathology & Clinical Pathology
Education:
University of Illinois at Chicago (1976)

Publications

Us Patents

Growth Of Foreign Cells In Fetal Animals Facilitated By Conditional And Selective Destruction Of Native Host Cells

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US Patent:
7626075, Dec 1, 2009
Filed:
Sep 17, 2003
Appl. No.:
10/527587
Inventors:
William E. Beschorner - Omaha NE, US
Carlos E. Sosa - Omaha NE, US
Scott C. Thompson - Omaha NE, US
Assignee:
Ximerex, Inc. - Blair NE
International Classification:
A01K 67/00
C12N 5/00
C12N 5/08
US Classification:
800 8, 435325, 435370
Abstract:
Foreign cells can be grown in fetal non-mammalian hosts for the production of transplant organs and tissues, the development of new therapeutic agents, and the production of biological factors and drugs. Tissue-specific injury to fetal host target cells is carried without substantial injury to the maternal host or foreign cells, providing an environment in which the injured tissue can be regenerated with the foreign cells.

Pre-Transplant Accommodated Organs Resistant To Anti-Donor Immunity

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US Patent:
7807463, Oct 5, 2010
Filed:
Jan 25, 2001
Appl. No.:
10/181896
Inventors:
William E. Beschorner - Omaha NE, US
Assignee:
The Board of Regents of The University of Nebraska - Omaha NE
International Classification:
A61K 35/32
US Classification:
435377, 424549
Abstract:
This invention includes the composition of organ grafts accommodated prior to transplantation and therefore resistant to rejection by preformed antibodies. Accommodation is achieved within the donor animal by administration of sub-lethal levels of accommodation inducing factors derived from animals sensitized to the donor.

Pre-Transplant Accomodated Organs Resistant To Anti-Donor Immunity

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US Patent:
8039257, Oct 18, 2011
Filed:
Oct 4, 2010
Appl. No.:
12/897297
Inventors:
William E Beschorner - Omaha NE, US
Assignee:
The Board of Regents of the University of Nebraska - Omaha NE
International Classification:
A61K 35/32
US Classification:
435377, 424549
Abstract:
This invention includes the composition of organ grafts accommodated prior to transplantation and therefore resistant to rejection by preformed antibodies. Accommodation is achieved within the donor animal by administration of sub-lethal levels of accommodation inducing factors derived from animals sensitized to the donor.

Transgenic Mammals Expressing Human Preproinsulin

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US Patent:
20090214482, Aug 27, 2009
Filed:
Apr 11, 2006
Appl. No.:
11/918281
Inventors:
William Beschorner - Omaha NE, US
Patrick E. Kudlacek - Omaha NE, US
Assignee:
XIMEREX, inc. - Blair NE
International Classification:
A61K 35/12
A01K 67/027
C07H 21/04
C12N 5/10
US Classification:
424 937, 800 14, 800 17, 536 235, 536 232, 435366
Abstract:
Transgenic mammals which express human preproinsulin, methods and reagents for producing the transgenic mammals, and therapeutic methods of providing patients with insulin and C-peptide using tissues and cells from the transgenic mammals.

Growth Of Foreign Cells After Conditional And Selective Destruction Of Fetal Host Cells

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US Patent:
20100075414, Mar 25, 2010
Filed:
Nov 17, 2009
Appl. No.:
12/620203
Inventors:
William E. Beschorner - Omaha NE, US
Carlos E. Sosa - Omaha NE, US
Scott C. Thompson - Omaha NE, US
Assignee:
XIMEREX, INC. - Omaha NE
International Classification:
C12N 5/07
US Classification:
435352, 435375, 435363
Abstract:
Foreign cells can be grown in fetal non-mammalian hosts for the production of transplant organs and tissues, the development of new therapeutic agents, and the production of biological factors and drugs. Tissue-specific injury to fetal host target cells is carried without substantial injury to the maternal host or foreign cells, providing an environment in which the injured tissue can be regenerated with the foreign cells.

Pre-Transplant Accommodated Organs Resistant To Anti-Donor Immunity

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US Patent:
20120270202, Oct 25, 2012
Filed:
Oct 17, 2011
Appl. No.:
13/274504
Inventors:
William E. Beschorner - Omaha NE, US
Susan Beschomer - Omaha NE, US
Assignee:
The Board of Regents of the University of Nebraska - Omaha NE
International Classification:
C12N 5/071
C12N 5/078
C12N 5/079
A61F 2/02
C12N 5/077
US Classification:
435 11, 435325
Abstract:
This invention includes the composition of organ grafts accommodated prior to transplantation and therefore resistant to rejection by preformed antibodies. Accommodation is achieved within the donor animal by administration of sub-lethal levels of accommodation inducing factors derived from animals sensitized to the donor.

Method Induction Of Antigen-Specific Immune Tolerance

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US Patent:
55975631, Jan 28, 1997
Filed:
Dec 18, 1995
Appl. No.:
8/573648
Inventors:
William E. Beschorner - Baldwin MD
International Classification:
A61K 3900
A61K 3822
A61K 3528
US Classification:
424 937
Abstract:
A method for inducing antigen-specific immune tolerance by depletion of resident thymic antigen presenting cells (APCs) and re-population of thymus with new APCs containing the antigen for tolerance is described.

Surrogate Tolerogenesis For The Development Of Tolerance To Xenografts

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US Patent:
60600497, May 9, 2000
Filed:
Jun 6, 1995
Appl. No.:
8/295899
Inventors:
William E. Beschorner - Baldwin MD
Assignee:
Ximerex, Inc. - Omaha NE
International Classification:
A61K 4800
C12N 1500
A01N 102
US Classification:
424 9321
Abstract:
This invention provides a method for developing immune tolerance in xenogeneic organ graft recipients, in which lympho-hematopoietic cells from an intended organ graft recipient are differentiated within a xenogeneic surrogate, such as a fetal animal. After birth of the surrogate, the matured lympho-hematopoietic cells containing antigen specific regulatory cells, including suppressor cells, veto cells, select B cells, anti-idiotype antibodies, and other related factors responsible for antigen specific tolerance in a surrogate animal are reintroduced into the intended organ graft recipient, in conjunction with an organ transplant or a tissue transplant from the xenograft surrogate. The invention also provides an organ graft repopulated with cells from the intended organ graft recipient produced in a surrogate animal.
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William F Beschorner from Omaha, NE, age ~48 Get Report