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Warren R Mikulka

from Brewster, NY
Age ~79
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Also known as:
Warren Mikulka Revocable, Larren R Mikulka, Warren R Mikula
Phone and address:
33 Karlsen Lake Rd, Sears Corners, NY 10509
(845) 278-9157
Related to:
Marian MikulkaWm M Mikulka
Connected to:
Colleen T Mikulka, 71John M Mikulla, 76Andrzej J Mikulski, 56Barbara P Mikulskis, 63Daniel Mikulski, 65Heidi M Mikulsky, 41Jennifer L Mikulski, 50Kristie L Mikulski, 47Lisa M Mikulsky, 63Mark A Mikulskis, 55

Warren Mikulka Phones & Addresses

  • 33 Karlsen Lake Rd, Brewster, NY 10509 (845) 278-9157
  • 83 Boston Ave, Massapequa, NY 11758
  • 3291 Riverland Rd, Fort Lauderdale, FL 33312 (954) 587-0950

Publications

Us Patents

High Affinity Human Antibodies To Human Il-18 Receptor

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US Patent:
7615220, Nov 10, 2009
Filed:
Apr 6, 2007
Appl. No.:
11/784308
Inventors:
Tammy H. Huang - Golden Bridge NY, US
Sean Stevens - Mohegan Lake NY, US
Joel H. Martin - Putnam Valley NY, US
Jeanette L. Fairhurst - White Plains NY, US
Kevin J. Pobursky - Beacon NY, US
Margaret Karow - Camarillo CA, US
Joan A. Windsor - Brooklyn NY, US
Warren R. Mikulka - Brewster NY, US
Assignee:
Regeneron Pharmaceuticals, Inc. - Tarrytown NY
International Classification:
A61K 39/395
C07K 16/28
US Classification:
4241431, 4241411, 53038822
Abstract:
An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18Rα), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.

High Affinity Human Antibodies To Human Il-4 Receptor

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US Patent:
7794717, Sep 14, 2010
Filed:
Sep 4, 2009
Appl. No.:
12/554029
Inventors:
Sean Stevens - Mohegan Lake NY, US
Tammy T. Huang - Golden Bridge NY, US
Joel H. Martin - Putnam Valley NY, US
Jeanette L. Fairhurst - White Plains NY, US
Ashique Rafique - Yonkers NY, US
Marcela Torres - New Milford NJ, US
Kevin J. Pobursky - Beacon NY, US
Raymond W. Leidich - Middletown NY, US
Joan A. Windsor - Brooklyn NY, US
Warren R. Mikulka - Brewster NY, US
Diana M. Ahrens - Mahopac NY, US
Ergang Shi - Ossining NY, US
Nicholas J. Papadopoulos - LaGrangeville NY, US
Assignee:
Regeneron Pharmaceuticals, Inc. - Tarrytown NY
International Classification:
A61K 39/00
US Classification:
4241331, 4241431, 5303873, 53038822
Abstract:
The present invention provides methods for treating one or more diseases or disorders which are improved, inhibited or ameliorated by reducing interleukin-4 (IL-4) activity. The methods of the invention comprise administering to a patient an antibody, or antigen-binding fragment thereof, which specifically binds to a human IL-4 receptor.

High Affinity Human Antibodies To Human Il-18 Receptor

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US Patent:
8003103, Aug 23, 2011
Filed:
Oct 13, 2009
Appl. No.:
12/577788
Inventors:
Tammy H. Huang - Golden Bridge NY, US
Sean Stevens - Mohegan Lake NY, US
Joel H. Martin - Putnam Valley NY, US
Jeanette L. Fairhurst - White Plains NY, US
Kevin J. Pobursky - Beacon NY, US
Margaret Karow - Camarillo CA, US
Joan A. Windsor - Brooklyn NY, US
Warren R. Mikulka - Brewster NY, US
Assignee:
Regeneron Pharmaceuticals, Inc. - Tarrytown NY
International Classification:
A61K 39/395
C07K 16/28
US Classification:
4241431, 4241411, 53038822
Abstract:
An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18Rα), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.

High Affinity Human Antibodies To Human Il-4 Receptor

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US Patent:
8092802, Jan 10, 2012
Filed:
Jun 23, 2010
Appl. No.:
12/821499
Inventors:
Sean Stevens - Mohegan Lake NY, US
Tammy T. Huang - Golden Bridge NY, US
Joel H. Martin - Putnam Valley NY, US
Jeanette L. Fairhurst - White Plains NY, US
Ashique Rafique - Yonkers NY, US
Marcela Torres - New Milford NJ, US
Kevin J. Pobursky - Beacon NY, US
Raymond W. Leidich - Middletown NY, US
Joan A. Windsor - Brooklyn NY, US
Warren R. Mikulka - Brewster NY, US
Diana M. Ahrens - Mahopac NY, US
Ergang Shi - Ossining NY, US
Nicholas J. Papadopoulos - LaGrangeville NY, US
Assignee:
Regeneron Pharmaceuticals, Inc. - Tarrytown NY
International Classification:
A61K 39/00
US Classification:
4241331, 4241431, 5303873, 53038822
Abstract:
The present invention provides methods for treating one or more diseases or disorders which are improved, inhibited or ameliorated by reducing interleukin-4 (IL-4) activity. The methods of the invention comprise administering to a patient an antibody, or antigen-binding fragment thereof, which specifically binds to a human IL-4 receptor.

High Affinity Human Antibodies To Human Il-4 Receptor

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US Patent:
8338135, Dec 25, 2012
Filed:
Dec 2, 2011
Appl. No.:
13/309594
Inventors:
Sean Stevens - San Francisco CA, US
Tammy T. Huang - Goldens Bridge NY, US
Joel H. Martin - Putnam Valley NY, US
Jeanette L. Fairhurst - White Plains NY, US
Ashique Rafique - Yonkers NY, US
Marcela Torres - Congers NY, US
Kevin J. Pobursky - Beacon NY, US
Raymond W. Leidich - Middletown NY, US
Joan A. Windsor - Princeton NJ, US
Warren R. Mikulka - Brewster NY, US
Diana M. Ahrens - Mahopac NY, US
Ergang Shi - Ossining NY, US
Nicholas J. Papadopoulos - LaGrangeville NY, US
Assignee:
Regeneron Pharmaceuticals, inc. - Tarrytown NY
International Classification:
C12P 21/08
US Classification:
435 691, 536 235, 4353201, 435325, 435358, 435243, 43525233, 530350, 5303871, 5303873, 5303879
Abstract:
An isolated human antibody or antigen binding fragment thereof which binds to human interleukin-4 receptor alpha (hIL-4Rα) with an affinity constant (K) of less than 200 pM, as measured by surface plasmon resonance, is provided.

High Affinity Human Antibodies To Human Il-4 Receptor

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US Patent:
20080160035, Jul 3, 2008
Filed:
Oct 2, 2007
Appl. No.:
11/906517
Inventors:
Sean Stevens - Mohegan Lake NY, US
Tammy T. Huang - Golden Bridge NY, US
Joel H. Martin - Putnam Valley NY, US
Jeanette L. Fairhurst - White Plains NY, US
Ashique Rafique - Yonkers NY, US
Marcela Torres - New Milford NY, US
Kevin J. Pobursky - Beacon NY, US
Raymond W. Leidich - Middletown NY, US
Joan A. Windsor - Brooklyn NY, US
Warren R. Mikulka - Brewster NY, US
Dina M. Ahrens - Mahopac NY, US
Ergang Shi - Ossining NY, US
Nicholas J. Papadopoulos - LaGrangeville NY, US
International Classification:
A61K 39/395
C07K 16/18
C12N 15/00
A61P 1/00
A61P 17/00
A61P 19/00
A61P 9/00
C12N 5/06
C12P 21/04
US Classification:
4241721, 5303879, 5303873, 4353201, 435325, 435 696
Abstract:
An isolated human antibody or antibody fragment thereof which binds to human interleukin-4 receptor alpha (hIL-4Rα) with an affinity constant (K) of less than 200 pM, as measured by surface plasmon resonance.
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Warren R Mikulka from Brewster, NY, age ~79 Get Report