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Viorel Mihalef

from North Brunswick, NJ
Age ~52
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Also known as:
Vierel Mihalef, Viorel Michalef, Viorel Mihalet, Mihalef Viorel
Phone and address:
18 Woodmere Rd, New Brunswick, NJ 08902
Connected to:
Dawn A Mihalek, 59Jeannette M Mihalek, 47Leslie C Mihalek, 64Stefanie Mihalek, 42Thomas Mihalenko, 61Earl D Mihali, 76Ilie Mihali, 63Janet M Mihalics, 81Joseph P Mihalich, 78Maria T Mihalic, 41

Viorel Mihalef Phones & Addresses

  • 18 Woodmere Rd, N Brunswick, NJ 08902
  • North Brunswick, NJ
  • Keasbey, NJ
  • E Brunswick, NJ
  • Somerset, NJ
  • 4317 Spruce St, Philadelphia, PA 19104
  • 4418 Spruce St, Philadelphia, PA 19104

Publications

Us Patents

Method And System For Non-Invasive Assessment Of Coronary Artery Disease

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US Patent:
20120072190, Mar 22, 2012
Filed:
Sep 7, 2011
Appl. No.:
13/226779
Inventors:
Puneet Sharma - Rahway NJ, US
Bogdan Georgescu - Plainsboro NJ, US
Viorel Mihalef - Keasbey NJ, US
Terrence Chen - Princeton NJ, US
Dorin Comaniciu - Princeton Junction NJ, US
Assignee:
Siemens Corporation - Iselin NJ
International Classification:
G06G 7/60
G06F 17/10
G06F 17/11
G06G 7/57
US Classification:
703 2, 703 9
Abstract:
A method and system for non-invasive patient-specific assessment of coronary artery disease is disclosed. An anatomical model of a coronary artery is generated from medical image data. A velocity of blood in the coronary artery is estimated based on a spatio-temporal representation of contrast agent propagation in the medical image data. Blood flow is simulated in the anatomical model of the coronary artery using a computational fluid dynamics (CFD) simulation using the estimated velocity of the blood in the coronary artery as a boundary condition.

Method And System For Patient-Specific Computational Modeling And Simulation For Coupled Hemodynamic Analysis Of Cerebral Vessels

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US Patent:
20120203530, Aug 9, 2012
Filed:
Feb 6, 2012
Appl. No.:
13/366677
Inventors:
Puneet Sharma - Rahway NJ, US
Tommaso Mansi - Westfield NJ, US
Viorel Mihalef - Keasbey NJ, US
Jingdan Zhang - Plainsboro NJ, US
David Liu - Princeton NJ, US
Shaohua Kevin Zhou - Plainsboro NJ, US
Bogdan Georgescu - Plainsboro NJ, US
Dorin Comaniciu - Princeton Junction NJ, US
Assignee:
Siemens Corporation - Iselin NJ
International Classification:
G06G 7/60
US Classification:
703 9
Abstract:
A method and system for patient-specific computational modeling and simulation for coupled hemodynamic analysis of cerebral vessels is disclosed. An anatomical model of a cerebral vessel is extracted from 3D medical image data. The anatomical model of the cerebral vessel includes an inner wall and an outer wall of the cerebral vessel. Blood flow in the cerebral vessel and deformation of the cerebral vessel wall are simulated using coupled computational fluid dynamics (CFD) and computational solid mechanics (CSM) simulations based on the anatomical model of the cerebral vessel.

Method And System For Multi-Scale Anatomical And Functional Modeling Of Coronary Circulation

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US Patent:
20130132054, May 23, 2013
Filed:
Nov 9, 2012
Appl. No.:
13/672781
Inventors:
Puneet Sharma - Rahway NJ, US
Lucian Mihai Itu - Princeton NJ, US
Bogdan Georgescu - Plainsboro NJ, US
Viorel Mihalef - Keasbey NJ, US
Ali Kamen - Skillman NJ, US
Dorin Comaniciu - Princeton Junction NJ, US
International Classification:
G06F 19/12
US Classification:
703 9
Abstract:
A method and system for multi-scale anatomical and functional modeling of coronary circulation is disclosed. A patient-specific anatomical model of coronary arteries and the heart is generated from medical image data of a patient. A multi-scale functional model of coronary circulation is generated based on the patient-specific anatomical model. Blood flow is simulated in at least one stenosis region of at least one coronary artery using the multi-scale function model of coronary circulation. Hemodynamic quantities, such as fractional flow reserve (FFR), are computed to determine a functional assessment of the stenosis, and virtual intervention simulations are performed using the multi-scale function model of coronary circulation for decision support and intervention planning.

Method And System For Patient-Specific Hemodynamic Assessment Of Virtual Stent Implantation

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US Patent:
20130144573, Jun 6, 2013
Filed:
Dec 6, 2011
Appl. No.:
13/311989
Inventors:
Puneet Sharma - Rahway NJ, US
Viorel Mihalef - Keasbey NJ, US
Bogdan Georgescu - Plainsboro NJ, US
Dorin Comaniciu - Princeton Junction NJ, US
Assignee:
Siemens Corporation - Iselin NJ
International Classification:
G06G 7/60
G06F 17/10
US Classification:
703 2, 703 11, 703 9
Abstract:
A method and system for assessment of virtual stent implantation in an aortic aneurysm is disclosed. A patient-specific 4D anatomical model of the aorta is generated from the 4D medical imaging data. A model representing mechanical properties of the aorta wall is adjusted to reflect changes due to aneurysm growth at a plurality of time stages. A stable deformation configuration of the aorta is generated for each time stages by performing fluid structure interaction (FSI) simulations using the patient-specific 4D anatomical model at each time stage based on the adjusted model representing the mechanical properties of the aorta wall at each time stage. Virtual stent implantation is performed for each stable deformation configuration of the aorta and FSI simulations are performed for each virtual stent implantation.

Blood Flow Computation In Vessels With Implanted Devices

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US Patent:
20130191100, Jul 25, 2013
Filed:
Jan 18, 2013
Appl. No.:
13/744857
Inventors:
Viorel Mihalef - Keasbey NJ, US
Puneet Sharma - Rahway NJ, US
Thomas Redel - Poxdorf, DE
Ali Kamen - Skillman NJ, US
Assignee:
Siemens Aktiengesellschaft - Munich
Siemens Corporation - Iselin NJ
International Classification:
G06F 19/00
US Classification:
703 11
Abstract:
A method for modeling blood flow through a flow diverter includes receiving a medical image containing blood vessels. Vessel geometry is extracted from the received medical image. Inlets and outlets are tagged within the extracted vessel geometry. A desired flow diverter is selected. A model of the selected flow diverter is generated within the imaged blood vessel, the model representing the flow diverter as a tube having a porous surface characterized by a viscous resistance and an inertial resistance. A course of blood flow though the flow diverter is predicted based on the generated model, the extracted vessel geometry, and the tagged inlets and outlets.

Method And System For Advanced Measurements Computation And Therapy Planning From Medical Data And Images Using A Multi-Physics Fluid-Solid Heart Model

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US Patent:
20130197884, Aug 1, 2013
Filed:
Feb 1, 2013
Appl. No.:
13/757517
Inventors:
Tommaso Mansi - Westfield NJ, US
Viorel Mihalef - Keasbey NJ, US
Xudong Zheng - Plainsboro NJ, US
Bogdan Georgescu - Plainsboro NJ, US
Saikiran Rapaka - Eagleville PA, US
Puneet Sharma - Rahway NJ, US
Ali Kamen - Skillman NJ, US
Dorin Comaniciu - Princeton Junction NJ, US
Assignee:
Siemens Corporation - Iselin NJ
International Classification:
G06F 19/00
US Classification:
703 2
Abstract:
Method and system for computation of advanced heart measurements from medical images and data; and therapy planning using a patient-specific multi-physics fluid-solid heart model is disclosed. A patient-specific anatomical model of the left and right ventricles is generated from medical image patient data. A patient-specific computational heart model is generated based on the patient-specific anatomical model of the left and right ventricles and patient-specific clinical data. The computational model includes biomechanics, electrophysiology and hemodynamics. To generate the patient-specific computational heart model, initial patient-specific parameters of an electrophysiology model, initial patient-specific parameters of a biomechanics model, and initial patient-specific computational fluid dynamics (CFD) boundary conditions are marginally estimated. A coupled fluid-structure interaction (FSI) simulation is performed using the initial patient-specific parameters, and the initial patient-specific parameters are refined based on the coupled FSI simulation. The estimated model parameters then constitute new advanced measurements that can be used for decision making.

Method And System For Hemodynamic Assessment Of Aortic Coarctation From Medical Image Data

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US Patent:
20130243294, Sep 19, 2013
Filed:
Mar 14, 2013
Appl. No.:
13/826307
Inventors:
Kristof Ralovich - Munich, DE
Lucian Mihai Itu - Brasov, RO
Viorel Mihalef - Keasbey NJ, US
Puneet Sharma - Monmouth Junction NJ, US
Dime Vitanovski - Erlangen, DE
Waldemar Krawtschuk - Erlangen, DE
Dorin Comaniciu - Princeton Junction NJ, US
Assignee:
Siemens Aktiengesellschaft - Munich
Siemens Corporation - Iselin NJ
International Classification:
G06T 7/00
US Classification:
382131
Abstract:
A method and system for non-invasive hemodynamic assessment of aortic coarctation from medical image data, such as magnetic resonance imaging (MRI) data is disclosed. Patient-specific lumen anatomy of the aorta and supra-aortic arteries is estimated from medical image data of a patient, such as contrast enhanced MRI. Patient-specific aortic blood flow rates are estimated from the medical image data of the patient, such as velocity encoded phase-contrasted MRI cine images. Patient-specific inlet and outlet boundary conditions for a computational model of aortic blood flow are calculated based on the patient-specific lumen anatomy, the patient-specific aortic blood flow rates, and non-invasive clinical measurements of the patient. Aortic blood flow and pressure are computed over the patient-specific lumen anatomy using the computational model of aortic blood flow and the patient-specific inlet and outlet boundary conditions.

Computation Of Hemodynamic Quantities From Angiographic Data

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US Patent:
20140024932, Jan 23, 2014
Filed:
Jul 9, 2013
Appl. No.:
13/937313
Inventors:
Puneet Sharma - Monmouth Junction NJ, US
Xudong Zheng - Plainsboro NJ, US
Ali Kamen - Skillman NJ, US
Lucian Mihai Itu - Brasov, RO
Bogdan Georgescu - Plainsboro NJ, US
Dorin Comaniciu - Princeton Junction NJ, US
Thomas Redel - Poxdorf, DE
Saikiran Rapaka - Ewing NJ, US
Viorel Mihalef - Keasbey NJ, US
Jan Boese - Eckental, DE
Assignee:
SIEMENS AKTIENGESELLSCHAFT - Munich
SIEMENS CORPORATION - Iselin NJ
International Classification:
A61B 6/00
US Classification:
600431
Abstract:
Methods for computing hemodynamic quantities include: (a) acquiring angiography data from a patient; (b) calculating a flow and/or calculating a change in pressure in a blood vessel of the patient based on the angiography data; and (c) computing the hemodynamic quantity based on the flow and/or the change in pressure. Systems for computing hemodynamic quantities and computer readable storage media are described.
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Viorel Mihalef from North Brunswick, NJ, age ~52 Get Report