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Vineet B Rajgarhia

from Dublin, CA
Age ~57
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Also known as:
Vineet A
Phone and address:
9773 Reimers Way, Pleasanton, CA 94568
(925) 236-2027
Related to:
Ritu Shukla Rajgarhia, 45
Connected to:
Neha Rajgarhia, 42Rahul K Rajgarhia, 44Aparna M Rajgopal, 47Kapil Rajgor, 41Uday R Rajguru, 64Andrew W Rajhel, 61Lilian Raji, 47Mohamed Raji, 65Samira R Raji, 50Usman Raji, 31

Vineet Rajgarhia Phones & Addresses

  • 9773 Reimers Way, Dublin, CA 94568 (925) 236-2027
  • San Ramon, CA
  • Concord, CA
  • 21 Spencer St, Lebanon, NH 03766 (603) 442-9303 (603) 678-4554
  • 15 Summer St, Waltham, MA 02452
  • Kingsport, TN
  • Minnetonka, MN
  • Alameda, CA
  • Columbus, OH
  • 9773 Reimers Way, Dublin, CA 94568

Work

Company: Praj industries ltd. Jun 2019 Position: Senior vice-president, renewable chemicals and materials

Education

Degree: Master of Business Administration, Masters School / High School: London Business School 2008 to 2010

Skills

Biotechnology • R&D

Languages

English

Industries

Biotechnology

Resumes

Resumes

Vineet Rajgarhia Photo 1

Senior Vice-President, Renewable Chemicals And Materials

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Location:
9773 Reimers Way, Dublin, CA 94568
Industry:
Biotechnology
Work:
Praj Industries Ltd.
Senior Vice-President, Renewable Chemicals and Materials
Total Apr 1, 2011 - May 2018
Vp, Biotechnologies and Head of Biotechnology, R and D
Bio Architecture Lab Apr 2010 - Apr 2011
Senior Vice President, R and D
Mascoma Llc Sep 2006 - Apr 2010
Vice President, R and D
Cubist Pharmaceuticals Aug 2004 - Aug 2006
Group Leader - Research Fermentation
Education:
London Business School 2008 - 2010
Master of Business Administration, Masters Columbia Business School 2008 - 2010
Master of Business Administration, Masters The Ohio State University 1991 - 1997
Doctorates, Doctor of Philosophy, Microbiology University of Maryland - Baltimore 1990 - 1991
Master of Science, Masters, Chemistry University of Mumbai 1986 - 1990
Bachelors, Bachelor of Science, Pharmacy
Skills:
Biotechnology
R&D
Languages:
English

Publications

Us Patents

Gene Knockout Mesophilic And Thermophilic Organisms, And Methods Of Use Thereof

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US Patent:
8435770, May 7, 2013
Filed:
May 9, 2008
Appl. No.:
12/599458
Inventors:
David Anthony Hogsett - Grantham NH, US
Vineet Badriphrajad Rajgarhia - Lebanon NH, US
Assignee:
Mascoma Corporation - Lebanon NH
International Classification:
C12P 7/06
C12N 1/20
C12N 15/00
C07H 21/04
US Classification:
435161, 4352523, 4353201, 536 232
Abstract:
One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce ethanol as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non-native gene encodes a first non-native enzyme involved in the metabolic production of ethanol. Another aspect of the invention relates to a process for converting lignocellulosic biomass to ethanol, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism.

Isolation And Characterization Of Cellobiohydrolase I (Cbh 1)

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US Patent:
8470592, Jun 25, 2013
Filed:
Jul 7, 2009
Appl. No.:
13/003199
Inventors:
Elena E. Brevnova - Lebanon NH, US
Jim Flatt - Colorado Springs CO, US
Chhayal Gandhi - Lebanon NH, US
Vineet Rajgarhia - Lebanon NH, US
John McBride - Lebanon NH, US
Anne Warner - Lebanon NH, US
Assignee:
Mascoma Corporation - Lebanon NH
International Classification:
C12N 15/00
C12N 9/00
C07H 21/04
C07K 14/00
US Classification:
4353201, 435183, 536 231, 530350
Abstract:
The present invention provides for the isolation and characterization of the cbh1 gene from. In particular, the present invention provides for the nucleic acid and amino acid sequences of cbh1, and domains, variants and derivatives thereof. The present invention further provides for the heterologous expression of Cbh1 in host cells, including yeast, e. g. ,. Expression of Cbh1 in host cells will augment cellulose digestion and facilitate ethanol production by those host cells on cellulosic substrates. In certain embodiments, heterologous expression in is in coordination with heterologous expression of other known, or newly identified saccharolytic enzymes. Therefore, the present invention also provides that the novel Cbh1 gene can utilized in a consolidated bioprocessing system.

Heterologous Expression Of Termite Cellulases Yeast

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US Patent:
20120003701, Jan 5, 2012
Filed:
Jul 7, 2009
Appl. No.:
13/003200
Inventors:
Elena E. Brevnova - Lebanon NH, US
Vineet Rajgarhia - Lebanon NH, US
Mark Mellon - Grantham NH, US
Anne Warner - Lebanon NH, US
John Mcbride - Lebanon NH, US
Chhayal Gandhi - Lebanon NH, US
Erin Wiswall - Danbury NH, US
Assignee:
MASCOMA CORPORATION - Lebanon NH
International Classification:
C12P 7/10
C12P 19/14
C12N 1/19
C12N 15/56
C12N 15/81
US Classification:
435 99, 536 232, 4353201, 4352542, 435165
Abstract:
The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast . The cellulases can also be co-expressed in host cells with other cellulases. The expression in such host cells of the termite and termite-associated symbiont cellulases, and variants and combinations thereof, result in yeast with improved cellulosic activity. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.

Gene Knockout Mesophilic And Thermophilic Organisms, And Methods Of Use Thereof

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US Patent:
20120094343, Apr 19, 2012
Filed:
Nov 12, 2009
Appl. No.:
13/129085
Inventors:
David A. Hogsett - Grantham NH, US
Vineet Rajgarhia - Lebanon NH, US
Nicky C. Caiazza - Rancho Santa Fe CA, US
Assignee:
Mascoma Corporation - Lebanon NH
International Classification:
C12P 7/56
C12P 7/54
C12N 1/21
C12N 15/11
C12N 15/74
US Classification:
435139, 536 231, 4353201, 4352523, 43525231, 435140
Abstract:
One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce lactate or acetate as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non-native gene encodes a first non-native enzyme involved in the metabolic production of lactate or acetate. Another aspect of the invention relates to a process for converting lignocellulosic biomass to lactate or acetate, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism.

Yeast Expressing Cellulases For Simultaneous Saccharification And Fermentation Using Cellulose

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US Patent:
20120129229, May 24, 2012
Filed:
Nov 23, 2009
Appl. No.:
13/130549
Inventors:
John McBride - Lyme NH, US
Elena Brevnova - Lebanon NH, US
Mark Mellon - Grantham NH, US
Allan Froehlich - Lebanon NH, US
Kristen Deleault - Canaan NH, US
Vineet Rajgarhia - Dublin CA, US
Riaan Den Haan - Durbanville, ZA
Merja Penttila - Helsinki, FI
Marja Ilmen - Helsinki, FI
Matti Siika-Aho - Helsinki, FI
Jaana Uusitalo - Espoo, FI
Emily A. Stonehouse - Lebanon NH, US
Alan Gilbert - Cambridge MA, US
Haowen Xu - Lebanon NH, US
Deidre Willes - Lebanon NH, US
John Bardsley - Newport NH, US
Anu Koivula - Helsinki, FI
Sanni Voutilainen - Siuntio, FI
International Classification:
C12N 1/19
C12P 19/02
US Classification:
435105, 4352542
Abstract:
Host cells, comprising expressing heterologous cellulases produce ethanol from cellulose In addition, multiple host cells expressing different heterlogous cellulases can be co-cultured together and used to produce ethanol from cellulose The recombinant yeast strains and co-cultures of the yeast strains can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of sacchanfication and fermentation processes

Yeast Cells Expressing An Exogenous Cellulosome And Methods Of Using The Same

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US Patent:
20120142046, Jun 7, 2012
Filed:
Feb 18, 2010
Appl. No.:
13/201257
Inventors:
John McBride - Lyme NH, US
Mark Mellon - Grantham NH, US
Vineet Rajgarhia - Dublin CA, US
Elena E. Brevnova - Lebanon NH, US
Erin Wiswall - Danbury NH, US
David A. Hogsett - Grantham NH, US
Danie LaGrange - Durbanville, ZA
Shaunita Rose - Strand, ZA
Emile Van Zyl - Stellenbosch, ZA
International Classification:
C12P 7/10
C12P 39/00
C12N 9/96
C12P 1/00
C12N 1/19
C12N 1/13
US Classification:
435 42, 4352542, 43525421, 43525422, 43525423, 4352572, 435188, 435 41, 435165
Abstract:
The present invention relates to the engineering and expression of heterologous cellulosomes in microorganisms in order to facilitate the conversion of biomass to useful products. In some embodiments, the invention relates to the expression of scaffoldin proteins which form the nucleus of a cellulosome. Cellulases or other biomass-degrading enzymes can be non-covalently linked to the scaffoldin protein by virtue of a dockerin domain-cohesin domain interaction.

Mesophilic And Thermophilic Organisms Modified To Produce Acrylate, And Methods Of Use Thereof

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US Patent:
20120149077, Jun 14, 2012
Filed:
Mar 12, 2010
Appl. No.:
13/256297
Inventors:
Vineet Rajgarhia - Dublin CA, US
Assignee:
Mascoma Corporation - Lebanon NH
International Classification:
C12P 7/40
C12N 15/74
C12N 1/21
US Classification:
435136, 4352523, 43525231, 4353201
Abstract:
The present invention provides for novel metabolic pathways leading to acrylate formation in a consolidated bio-processing system (CBP) where lignocellulosic biomass is efficiently converted to acrylate. In one such metabolic pathway, pyruvate is converted to lactate, which is converted to lactoyol-CoA, which is converted to acryloyl-CoA, and which is finally converted to acrylate. In another such metabolic pathway, pyruvate is converted to L-α-alanine, which is converted to L-aspartate, which is converted to β-alanine, which is converted to β-alanyl-CoA, which is converted to acryloyl-CoA, and which is finally converted to acrylate. In yet another metabolic pathway, pyruvate is converted to lactate, and then lactate is converted directly to acrylate. In certain aspects, the invention provides for heterologous expression of one or more enzymes in a mesophilic or thermophilic organism, such as or , where the one or more enzymes functions within a novel metabolic pathway as described above to convert pyruvate to acrylate via lactate, or via β alanine and acryloyl-CoA.

Production Of Propanols, Alcohols, And Polyols In Consolidated Bioprocessing Organisms

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US Patent:
20120322078, Dec 20, 2012
Filed:
Aug 20, 2010
Appl. No.:
13/391554
Inventors:
John E. Mcbride - Lyme NH, US
Vineet Rajgarhia - Dublin CA, US
Arthur J. Shaw - Grantham NH, US
Shital A. Tripathi - Berkeley CA, US
Elena Brevnova - Lebanon NH, US
Nicky Caiazza - Lebanon NH, US
Johannes Pieter Van Dijken - Schiedam, NL
Allan C. Froehlich - Lebanon NH, US
William Ryan Sillers - Lebanon NH, US
James H. Flatt - Del Mar CA, US
International Classification:
C12P 7/04
C12P 7/18
C12Q 1/68
C12Q 1/527
C12N 1/19
C12N 1/21
C12N 15/60
US Classification:
435 618, 4352523, 435158, 536 232, 435157, 435 4, 43525231, 43525421, 4352542, 43525423, 43525422
Abstract:
The present invention provides for novel metabolic pathways leading to propanol, alcohol or polyol formation in a consolidated bioprocessing system (CBP), where lignocellulosic biomass is efficiently converted to such products. More specifically, the invention provides for a recombinant microorganism, where the microorganism expresses one or more native and/or heterologous enzymes; where the one or more enzymes function in one or more engineered metabolic pathways to achieve: (1) conversion of a carbohydrate source to 1,2-propanediol, isopropropanol, ethanol and/or glycerol; (2) conversion of a carbohydrate source to n-propanol and isopropanol; (3) conversion of a carbohydrate source to isopropanol and methanol; or (4) conversion of a carbohydrate source to propanediol and acetone; wherein the one or more native and/or heterologous enzymes is activated, up-regulated or down-regulated.
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Vineet B Rajgarhia from Dublin, CA, age ~57 Get Report