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Tracy Fang Shing Kuo

from Irvine, CA
Age ~56

Tracy Kuo Phones & Addresses

  • 14 Russell Ct, Irvine, CA 92617 (650) 722-2305
  • Newport Beach, CA
  • Palo Alto, CA
  • San Diego, CA
  • Mountain View, CA
  • La Jolla, CA
  • Tucson, AZ
  • Linden, NJ

Work

Address: 19742 Macarthur Blvd, Irvine, CA 92612 Specialities: Psychologist

Languages

English

Specialities

Clinical Psychology • Adult Development & Aging Psychology • Clinical Child & Adolescent Psychology • Clinical Neuropsychology • Cognitive & Behavioral Psychology • Counseling • Group Psychotherapy • Neuropsychology • Psychology • Psychotherapy

Professional Records

Medicine Doctors

Tracy Kuo Photo 1

Dr. Tracy F Kuo, Irvine CA - PHD

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Specialties:
Clinical Psychology
Adult Development & Aging Psychology
Clinical Child & Adolescent Psychology
Clinical Neuropsychology
Cognitive & Behavioral Psychology
Counseling
Group Psychotherapy
Neuropsychology
Psychology
Psychotherapy
Address:
19742 Macarthur Blvd Suite 111, Irvine, CA 92612
(949) 385-2020 (Phone), (949) 251-1102 (Fax)
Languages:
English
Tracy Kuo Photo 2

Tracy F Kuo, Irvine CA

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Specialties:
Psychologist
Address:
19742 Macarthur Blvd, Irvine, CA 92612

Resumes

Resumes

Tracy Kuo Photo 3

Clinical Psychologist, Sleep Disorders Specialist At Sleep Disorders And Behavioral Medicine Services

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Position:
Owner at Tracy Kuo, PhD, Clinical Psychologist, Sleep Disorders Specialist at Independent Practice
Location:
Orange County, California Area
Industry:
Mental Health Care
Work:
Tracy Kuo, PhD
Owner

Independent Practice since Aug 2009
Clinical Psychologist, Sleep Disorders Specialist

Stanford University School of Medicine Sep 2000 - Oct 2009
Clinical Assistant Professor
Education:
Stanford University School of Medicine 2000 - 2002
Postdoc, Sleep disorders medicine
University of Arizona 1993 - 2002
PhD, Clnical Psychology
University of California, San Diego 1987 - 1992
B.A., Psychology
Tracy Kuo Photo 4

Clinical Assistant Professor At Stanford University School Of Medicine

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Position:
Clinical Assistant Professor at Stanford University School of Medicine
Location:
Greater Los Angeles Area
Industry:
Mental Health Care
Work:
Stanford University School of Medicine
Clinical Assistant Professor

Stanford University School of Medicine Sep 2000 - Aug 2002
Postdoctoral Fellow
Education:
University of Arizona 1994 - 2000
PhD, Clinical Psychology (minor Clin Neuropsychology)

Business Records

Name / Title
Company / Classification
Phones & Addresses
Tracy F. Kuo
Phd , Principal
Tracy Kuo Ph.D
Nonclassifiable Establishments · Specialty Outpatient Clinic · Specialty Outpatient Clinics, Nec
19742 Macarthur Blvd, Irvine, CA 92612
Tracy Kuo
Manager
Office for Faculty Equity
College/University Admn Educational Program General Hospital
Accounting Office RM 206, Berkeley, CA 94720
(510) 642-2694

Publications

Us Patents

Combination Therapies For Treating Cancer

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US Patent:
20220363779, Nov 17, 2022
Filed:
May 12, 2022
Appl. No.:
17/743350
Inventors:
- South San Francisco CA, US
Bang Janet SIM - South San Francisco CA, US
Sophia RANDOLPH - Chico CA, US
Jaume PONS - San Francisco CA, US
Tracy Chia-Chien KUO - San Carlos CA, US
International Classification:
C07K 16/32
A61P 35/00
Abstract:
Provided are methods of treating cancer that comprise administering a polypeptide (e.g. a fusion polypeptide) that comprises a SIRPα D1 domain variant and an Fc domain variant in combination with at least one chemotherapy agent and/or at least one therapeutic antibody. Also provided are related kits.

Antibodies Against Signal-Regulatory Protein Alpha And Methods Of Use

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US Patent:
20220324996, Oct 13, 2022
Filed:
Feb 22, 2022
Appl. No.:
17/677873
Inventors:
- South San Francisco CA, US
Bang Janet SIM - South San Francisco CA, US
Hong WAN - Foster City CA, US
Tracy Chia-Chien KUO - San Carlos CA, US
International Classification:
C07K 16/28
A61P 35/00
Abstract:
Provided herein, inter alia, are isolated, humanized antibodies that bind an extracellular domain of a human SIRP-α polypeptide. Also provided are polynucleotides, vectors, host cells, and methods of production and use related thereto.

Transglutaminase-Mediated Conjugation

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US Patent:
20230130194, Apr 27, 2023
Filed:
Jun 16, 2022
Appl. No.:
17/842573
Inventors:
- Burlingame CA, US
Hong I. WAN - Foster City CA, US
Tracy Chia-Chien KUO - San Mateo CA, US
Curt W. BRADSHAW - San Francisco CA, US
Son LAM - San Francisco CA, US
Bang Janet SIM - Brisbane CA, US
Edward HyungSuk HA - Cambridge MA, US
Sukumar SAKAMURI - San Diego CA, US
International Classification:
A61K 47/68
C07K 16/30
Abstract:
The present disclosure provides for antibody-oligonucleotide conjugates, methods of preparation thereof, and methods of use thereof. Also provided are related compounds, compositions and kits.

Antibodies Against Signal-Regulatory Protein Alpha And Methods Of Use

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US Patent:
20230018821, Jan 19, 2023
Filed:
Jun 2, 2021
Appl. No.:
17/337180
Inventors:
- Bulingame CA, US
Bang Janet SIM - Brisbane CA, US
Hong WAN - Foster City CA, US
Tracy Chia-Chien KUO - San Mateo CA, US
Steven Elliot KAUDER - San Mateo CA, US
William Don HARRIMAN - Alameda CA, US
Shelley IZQUIERDO - Berkeley CA, US
International Classification:
C07K 16/28
G01N 33/68
Abstract:
Provided herein, inter alia, are isolated antibodies that bind an extracellular domain of a human SIRP-α v1 polypeptide (e.g., the D1 domain), an extracellular domain of a human SIRP-α v2 polypeptide, or both. In some embodiments, the antibodies also bind an extracellular domain of a monkey SIRP-α polypeptide, an extracellular domain of a mouse SIRP-α polypeptide, an extracellular domain of a human SIRP-β polypeptide, and/or an extracellular domain of a human SIRP-γ polypeptide. In some embodiments, the antibodies block or do not binding between an extracellular domain of a human SIRP-α polypeptide and an IgSF domain of a human CD47 polypeptide, while in some embodiments, the antibodies reduce the affinity of a human SIRP-α polypeptide for binding an IgSF domain of a human CD47 polypeptide. Further provided herein are methods, polynucleotides, vectors, and host cells related thereto.

Antibodies Against Signal-Regulatory Protein Alpha And Methods Of Use

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US Patent:
20210363269, Nov 25, 2021
Filed:
Jun 2, 2021
Appl. No.:
17/337176
Inventors:
- Burlingame CA, US
Bang Janet SIM - Brisbane CA, US
Hong WAN - Foster City CA, US
Tracy Chia-Chien KUO - San Mateo CA, US
Steven Elliot KAUDER - San Mateo CA, US
William Don HARRIMAN - Alameda CA, US
Shelley IZQUIERDO - Berkeley CA, US
International Classification:
C07K 16/28
G01N 33/68
Abstract:
Provided herein, inter alia, are isolated antibodies that bind an extracellular domain of a human SIRP-α v1 polypeptide (e.g., the D1 domain), an extracellular domain of a human SIRP-α v2 polypeptide or both. In some embodiments, the antibodies also bind an extracellular domain of a monkey SIRP-α polypeptide, an extracellular domain of a SIRP-α polypeptide, an extracellular domain of a human SIRP-β polypeptide, and/or an extracellular domain of a human SIRP-γ polypeptide. In some embodiments, the antibodies block or do not binding between an extracellular domain of a human SIRP-α polypeptide and an IgSF domain of a human CD47 polypeptide, while in some embodiments, the antibodies reduce the affinity of a human SIRP-α polypeptide for binding an IgSF domain of a human CD47 polypeptide. Further provided herein are methods, polynucleotides, vectors, and host cells related thereto.

Combination Therapies For Treating Cancer

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US Patent:
20210154269, May 27, 2021
Filed:
Nov 25, 2020
Appl. No.:
17/105353
Inventors:
- Burlingame CA, US
Bang Janet SIM - Brisbane CA, US
Sophia RANDOLPH - Chico CA, US
Jaume PONS - San Francisco CA, US
Tracy Chia-Chien KUO - San Mateo CA, US
International Classification:
A61K 38/17
A61K 39/395
A61K 31/337
A61K 33/243
A61K 31/282
A61K 31/513
A61K 31/52
A61K 31/7068
A61K 31/7072
A61K 31/7076
A61K 31/17
A61K 31/519
A61K 31/517
A61P 35/00
Abstract:
Provided are methods of treating cancer that comprise administering a polypeptide (e.g. a fusion polypeptide) that comprises a SIRPα D1 domain variant and an Fc domain variant in combination with at least one chemotherapy agent and/or at least one therapeutic antibody. Also provided are related kits.

Constructs Having A Sirp-Alpha Domain Or Variant Thereof

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US Patent:
20210070838, Mar 11, 2021
Filed:
Mar 20, 2020
Appl. No.:
16/825850
Inventors:
- Burlingame CA, US
Laura DEMING - Palo Alto CA, US
Corey GOODMAN - Marshall CA, US
Bang Janet SIM - Brisbane CA, US
Steven Elliot KAUDER - San Mateo CA, US
Hong WAN - Foster City CA, US
Tracy Chia-Chien KUO - San Mateo CA, US
Assignee:
ALX Oncology Inc. - Burlingame CA
International Classification:
C07K 14/705
A61K 39/395
C07K 16/28
A61K 47/68
A61K 38/17
A61K 45/06
C07K 16/00
Abstract:
The present disclosure features signal-regulatory protein α (SIRP-α) polypeptides and constructs that are useful, e.g., to target a cell (e.g., a cancer cell or a cell of the immune system), to increase phagocytosis of the target cell, to eliminate immune cells such as regulatory T-cells, to kill cancer cells, to treat a disease (e.g., cancer) in a subject, or any combinations thereof. The SIRP-α constructs include a high affinity SIRP-α D1 domain or variant thereof that binds CD47 with higher affinity than a wild-type SIRP-α. The SIRP-α polypeptides or constructs include a SIRP-α D1 variant fused to an Fc domain monomer, a human serum albumin (HSA), an albumin-binding peptide, or a polyethylene glycol (PEG) polymer. Compositions provided herein include (i) a polypeptide including a signal-regulatory protein α (SIRP-α) D1 variant and (ii) an antibody.

Constructs Having A Sirp-Alpha Domain Or Variant Thereof

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US Patent:
20200239543, Jul 30, 2020
Filed:
Jan 7, 2020
Appl. No.:
16/736651
Inventors:
- Burlingame CA, US
Laura DEMING - Palo Alto CA, US
Corey GOODMAN - Marshall CA, US
Bang Janet SIM - Brisbane CA, US
Steven Elliot KAUDER - San Mateo CA, US
Hong WAN - Foster City CA, US
Tracy Chia-Chien KUO - San Mateo CA, US
International Classification:
C07K 14/705
C07K 16/28
C07K 16/00
A61K 45/06
A61K 39/395
A61K 38/17
A61K 47/68
Abstract:
The present disclosure features signal-regulatory protein α (SIRP-α) polypeptides and constructs that are useful, e.g., to target a cell (e.g., a cancer cell or a cell of the immune system), to increase phagocytosis of the target cell, to eliminate immune cells such as regulatory T-cells, to kill cancer cells, to treat a disease (e.g., cancer) in a subject, or any combinations thereof. The SIRP-α constructs include a high affinity SIRP-α D1 domain or variant thereof that binds CD47 with higher affinity than a wild-type SIRP-α. The SIRP-α polypeptides or constructs include a SIRP-α D1 variant fused to an Fc domain monomer, a human serum albumin (HSA), an albumin-binding peptide, or a polyethylene glycol (PEG) polymer. Compositions provided herein include (i) a polypeptide including a signal-regulatory protein α (SIRP-α) D1 variant and (ii) an antibody.
Tracy Fang Shing Kuo from Irvine, CA, age ~56 Get Report