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Timothy W Starzl

from Boulder, CO
Age ~69

Timothy Starzl Phones & Addresses

  • 5205 Holmes Pl, Boulder, CO 80303 (303) 447-0290
  • 4734 Jackson Cir, Boulder, CO 80303
  • 4830 Meredith Way APT 203, Boulder, CO 80303 (303) 506-5347

Work

Position: Executive, Administrative, and Managerial Occupations

Education

Degree: Bachelor's degree or higher

Publications

Us Patents

Sensing System For Specific Substance And Molecule Detection

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US Patent:
20010029050, Oct 11, 2001
Filed:
Jun 14, 2001
Appl. No.:
09/882396
Inventors:
Timothy Starzl - Boulder CO, US
David Nunnery - Westminster CO, US
MaryBeth Robinson - Boulder CO, US
H. Hanlin - Louisville CO, US
Assignee:
Accelr8 Technology Corporation
International Classification:
G01N033/543
US Classification:
436/518000
Abstract:
A system for detecting a specific substance or analyte of interest is provided that includes one or more sensing units and an instrument for analyzing the sensing units. Each sensing unit preferably includes a substrate, an attachment layer and at least one capture layer that includes a ligand layer. In one embodiment, the attachment layer is tripartite and includes a lower binding surface held to the substrate and an upper binding surface that holds the ligand layer, together with an insulating layer disposed between these two surfaces. The lower binding surface provides a durable and stable attachment to the substrate. The upper binding surface holds the ligand layer and does not jeopardize the integrity or viability thereof. The insulating layer prevents any unwanted interaction between the lower and upper binding surfaces. Each sensing unit is supported on a test piece received by the instrument. The instrument controllably positions the test piece using marks and/or codes on the test piece. The instrument measures a difference in mass in the sensing unit in connection with determining whether or not the analyte of interest is present. A light beam is used in making this measurement. In one embodiment, multiple reflections of the light beam on the same sensing unit are utilized to improve the sensitivity of the instrument. Mass enhancement techniques are also preferably utilized to effectively amplify the detected signal that is indicative of the analyte's presence. The system can also include a device for heating, humidifying and mixing materials of the sensing units, as well as preventing cross-contamination of the sensing units.

Combinatorial Query Generating System And Method

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US Patent:
20020103809, Aug 1, 2002
Filed:
Feb 2, 2001
Appl. No.:
09/776161
Inventors:
Timothy Starzl - Boulder CO, US
Ravi Starzl - Boulder CO, US
Assignee:
SearchLogic.com Corporation
International Classification:
G06F007/00
US Classification:
707/102000
Abstract:
An automated system and method for creating a topical data structure of documents or other items from an inter-linked system of documents, such as the Web and/or the Internet. The data structure can then be searched using conventional means information to generate highly relevant results. The system automatically utilizes pre-existing search resources to discover and collect topically relevant information from the inter-linked system of documents, which can be added to the topical data structure. The topically relevant information collected using the pre-existing search resources can be directly added to the data structure or can be further filtered for relevancy before being added to the data structure.

Enumeration Method Of Analyte Detection

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US Patent:
20030153023, Aug 14, 2003
Filed:
Feb 25, 2002
Appl. No.:
10/084632
Inventors:
Timothy Starzl - Boulder CO, US
Scott Clark - Denver CO, US
Mary Vellequette - Louisville CO, US
H. Hanlin - Louisville CO, US
Steven Metzger - Fort Collins CO, US
International Classification:
G01N033/53
G01N033/537
G01N033/543
G06F019/00
G06K009/00
US Classification:
435/007920, 382/128000, 702/019000
Abstract:
This invention is directed to an optically-based method and system for analyte detection using solid phase immobilization, specific analyte labels adapted for signal generation and corresponding processes for the utilization thereof. The enumeration detection method disclosed herein narrows the area for signal observation, thus, improving detectable signal to background ratio. The system is comprised of a platform/support for immobilizing a sample stage having a labeled sample (analyte complex) bound thereto, a radiation source, an optical apparatus for generating and directing radiation at said sample and a control that obtains data and then conducts analyses using digital image data. Upon engagement of the system, the sample generates a signal capable of differentiation from background signal, both of which are collected and imaged with a signal detector that generated a sample image to a data processing apparatus. This apparatus receives signal measurements and, in turn, enumerates individual binding events. Generated signal may be increased via selected mass enhancement. The invention, enumeration assay methodology detecting individual binding events, may be used, for example, in analyses to detect analyte or confirm results in both research, commercial and point of care applications.

Enumeration Method Of Analyte Detection

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US Patent:
20070298513, Dec 27, 2007
Filed:
Oct 23, 2006
Appl. No.:
11/552111
Inventors:
Timothy Starzl - Boulder CO, US
Scott Clark - Denver CO, US
Mary Vellequette - Louisville CO, US
H. Hanlin - Louisville CO, US
Steven Metzger - Fort Collins CO, US
Assignee:
Accelr8 Technology Corporation - Denver CO
International Classification:
G01N 21/01
US Classification:
436164000
Abstract:
This invention is directed to an optically-based method and system for analyte detection using solid phase immobilization, specific analyte labels adapted for signal generation and corresponding processes for the utilization thereof. The enumeration detection method disclosed herein narrows the area for signal observation, thus, improving detectable signal to background ratio. The system is comprised of a platform/support for immobilizing a sample stage having a labeled sample (analyte complex) bound thereto, a radiation source, an optical apparatus for generating and directing radiation at said sample and a control that obtains data and then conducts analyses using digital image data. Upon engagement of the system, the sample generates a signal capable of differentiation from background signal, both of which are collected and imaged with a signal detector that generated a sample image to a data processing apparatus. This apparatus receives signal measurements and, in turn, enumerates individual binding events. Generated signal may be increased via selected mass enhancement. The invention, enumeration assay methodology detecting individual binding events, may be used, for example, in analyses to detect analyte or confirm results in both research, commercial and point of care applications.

Compositions And Methods For Treatment In Broad-Spectrum, Undifferentiated Or Mixed Clinical Applications

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US Patent:
20120141458, Jun 7, 2012
Filed:
Nov 22, 2011
Appl. No.:
13/302836
Inventors:
Timothy W. Starzl - Boulder CO, US
Assignee:
PANTHERYX, INC. - Boulder CO
International Classification:
A61K 39/395
A61P 31/04
A61P 31/22
A61P 1/00
A61P 31/16
A61P 1/12
A61P 1/04
A61P 29/00
A61P 31/00
A61P 31/10
US Classification:
4241301
Abstract:
The disclosure provides improved compositions and methods for passive immunization. In embodiments, a composition comprising a synergistic combination of specific polyclonal antibodies in a carrier matrix is provided. The disclosure provides effective, economical compositions and methods for the treatment of diarrhea and enteric infections in broad-spectrum, undifferentiated, or mixed clinical applications.

Method For Specific Substance And Molecule Detection

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US Patent:
62743848, Aug 14, 2001
Filed:
Jul 6, 1999
Appl. No.:
9/346039
Inventors:
Timothy W. Starzl - Boulder CO
David W. Nunnery - Westminster CO
MaryBeth Robinson - Boulder CO
H. John Hanlin - Louisville CO
Assignee:
Accelr8 Technology Corporation - Denver CO
International Classification:
G01N 33543
US Classification:
436518
Abstract:
A system for detecting a specific substance or analyte of interest is provided that includes one or more sensing units and an instrument for analyzing the sensing units. Each sensing unit preferably includes a substrate, an attachment layer and at least one capture layer that includes a ligand layer. In one embodiment, the attachment layer is tripartite and includes a lower binding surface held to the substrate and an upper binding surface that holds the ligand layer, together with an insulating layer disposed between these two surfaces. The lower binding surface provides a durable and stable attachment to the substrate. The upper binding surface holds the ligand layer and does not jeopardize the integrity or viability thereof. The insulating layer prevents any unwanted interaction between the lower and upper binding surfaces. Each sensing unit is supported on a test piece received by the instrument.

Heat Detection For Animals Including Cows

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US Patent:
55424317, Aug 6, 1996
Filed:
Dec 30, 1993
Appl. No.:
8/176133
Inventors:
Timothy W. Starzl - Boulder CO
Marguerita Cattell - Loveland CO
Richard T. Mihran - Boulder CO
Loretta M. Zapp - Boulder CO
Assignee:
DDX Incorporated - Boulder CO
International Classification:
A61B 1000
US Classification:
128738
Abstract:
A system is disclosed for making determinations related to the heat cycle in a cow. The system includes an electronic patch attached to the cow. A transmitter module for transmitting heat mount data is contained in a pouch of the electronic patch. A removable and disposable battery is also contained in the pouch for powering the transmitter module. The heat mount data from the transmitter module is sent to a repeater module to maintain the quality of the transmitted heat mount data signal. The heat mount data is re-transmitted by the repeater module to a central receiver module which includes a memory for storing heat mount data. The heat mount data is downloaded to a computer upon request using software that is also used to analyze the heat mount data. Analysis of the heat mount data results in determining a value that is useful in deciding on the optimal time to breed the cow.

Sensing System For Specific Substance And Molecule Detection

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US Patent:
59587040, Sep 28, 1999
Filed:
Mar 12, 1997
Appl. No.:
8/820365
Inventors:
Timothy W. Starzl - Boulder CO
David W. Nunnery - Westminster CO
MaryBeth Robinson - Boulder CO
H. John Hanlin - Louisville CO
Assignee:
DDx, Inc. - Denver CO
International Classification:
G01N 3353
G01N 33543
US Classification:
435 71
Abstract:
A system for detecting a specific substance or analyte of interest is provided that includes one or more sensing units and an instrument for analyzing the sensing units. Each sensing unit preferably includes a substrate, an attachment layer and at least one capture layer that includes a ligand layer. In one embodiment, the attachment layer is tripartite and includes a lower binding surface held to the substrate and an upper binding surface that holds the ligand layer, together with an insulating layer disposed between these two surfaces. The lower binding surface provides a durable and stable attachment to the substrate. The upper binding surface holds the ligand layer and does not jeopardize the integrity or viability thereof. The insulating layer prevents any unwanted interaction between the lower and upper binding surfaces. Each sensing unit is supported on a test piece received by the instrument.
Timothy W Starzl from Boulder, CO, age ~69 Get Report