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Tianan Fang

from Newtown, PA
Age ~57
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Also known as:
Tian Fang, Pianan Fang, Tianan Fiang, An Fang Tian
Phone and address:
7 York St, Upper Makefield, PA 18940
(215) 968-4935
Related to:
Desong Yu, 45Joan M CarrollAndre M Thomas, 53Carol Moore, 63Edna Praster
Connected to:
Allen T Fang, 68Barbara Fang, 51Catherine H Fang, 48Cindy Y Fang, 45Cristina C Fang, 62Danny C Fang, 75Doris P Fang, 79Edward W Fang, 76Francis G Fang, 64Gina J Fang, 39

Tianan Fang Phones & Addresses

  • 7 York St, Newtown, PA 18940 (215) 968-4935
  • Levittown, PA
  • 2093 John Russell Cir, Elkins Park, PA 19027 (215) 885-9267
  • 2093B John Russell Cir, Elkins Park, PA 19027
  • Philadelphia, PA
  • Buck, PA
  • 7 York St, Newtown, PA 18940

Publications

Us Patents

Six-Membered Heterocycles Useful As Serine Protease Inhibitors

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US Patent:
20060009455, Jan 12, 2006
Filed:
Jun 13, 2005
Appl. No.:
11/151627
Inventors:
James Corte - Lawrenceville NJ, US
Jon Hangeland - Morrisville PA, US
Miml Quan - Yardley PA, US
Joanne Smallheer - Yardley PA, US
Tianan Fang - Levittown PA, US
International Classification:
A61K 31/513
A61K 31/498
A61K 31/4709
C07D 43/02
C07D 45/02
US Classification:
514249000, 514269000, 514345000, 544320000, 514341000, 544295000, 546148000, 514307000, 544353000
Abstract:
The present invention provides compounds of Formula (I): or a stereoisomer or pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, L, Z, X, X, X, X, and Xare as defined herein. The compounds of Formula (I) are useful as selective inhibitors of serine protease enzymes of the coagulation cascade and/or contact activation system; for example thrombin, factor Xa, factor XIa, factor IXa, factor VIIa and/or plasma kallikrein. In particular, it relates to compounds that are selective factor XIa inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.

Macrocycles As Factor Xia Inhibitors

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US Patent:
20120041190, Feb 16, 2012
Filed:
Feb 10, 2011
Appl. No.:
13/024544
Inventors:
James R. Corte - Lawrenceville NJ, US
Tianan Fang - Levittown PA, US
Carl P. Decicco - New Hope PA, US
Donald J.P. Pinto - Churchville PA, US
Karen A. Rossi - Newtown PA, US
Zilun Hu - Jamison PA, US
Yoon Jeon - Belle Mead NJ, US
Mimi L. Quan - Yardley PA, US
Joanne M. Smallheer - Yardley PA, US
Yufeng Wang - North Brunswick NJ, US
Wu Yang - Princeton Junction NJ, US
International Classification:
C07D 487/06
C07D 513/06
C07D 498/16
US Classification:
540456, 540468, 540477, 540472, 540469, 540460, 540461
Abstract:
The present invention provides compounds of Formula (I):or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein all the variables are as defined herein. These compounds are selective Factor XIa inhibitors or dual inhibitors of fXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.

Carbamoyloxymethyl Triazole Cyclohexyl Acids As Lpa Antagonists

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US Patent:
20220249443, Aug 11, 2022
Filed:
Apr 12, 2022
Appl. No.:
17/718760
Inventors:
- Princeton NJ, US
Jun Li - Pittsburgh PA, US
Jun Shi - San Diego CA, US
Yan Shi - Flourtown PA, US
Shiwei Tao - Hillsborough NJ, US
Hao Zhang - Belle Mead NJ, US
Suresh Dhanusu - Hosur, IN
Kumaravel Selvakumar - Bangalore, IN
Ramesh Babu Reddigunta - Chittoor District, IN
Steven J. Walker - Portage MI, US
Lawrence J. Kennedy - Titusville NJ, US
James R. Corte - Yardley PA, US
Tianan Fang - Newtown PA, US
Sutjano Jusuf - Princeton NJ, US
International Classification:
A61K 31/4192
C07D 401/14
C07D 249/06
A61K 31/27
A61K 31/454
C07D 401/04
Abstract:
The present invention provides compounds of Formula (I):or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Macrocycles As Factor Xia Inhibitors

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US Patent:
20230058729, Feb 23, 2023
Filed:
Oct 4, 2021
Appl. No.:
17/493516
Inventors:
- Princeton NJ, US
Tianan FANG - Newtown PA, US
Carl P. DECICCO - New Hope PA, US
Donald J.P. PINTO - Churchville PA, US
Karen A. ROSSI - Newtown PA, US
Zilun HU - Jamison PA, US
Yoon JEON - Belle Mead NJ, US
Mimi L. QUAN - Yardley PA, US
Joanne M. SMALLHEER - Yardley PA, US
Yufeng WANG - Belle Mead NJ, US
Wu YANG - Princeton Junction NJ, US
International Classification:
C07D 487/04
C07D 487/08
C07D 498/08
C07D 487/06
C07D 487/16
C07D 498/06
C07D 471/18
C07D 487/18
C07D 471/14
C07D 487/14
C07D 498/04
Abstract:
The present invention provides compounds of Formula (I):or a stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, wherein all the variables are as defined herein. These compounds are selective Factor XIa inhibitors or dual inhibitors of fXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.

Carbamoyloxymethyl Triazole Cyclohexyl Acids As Lpa Antagonists

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US Patent:
20210244711, Aug 12, 2021
Filed:
Apr 5, 2021
Appl. No.:
17/221859
Inventors:
- Princeton NJ, US
Jun Li - Pittsburgh PA, US
Jun Shi - San Diego CA, US
Yan Shi - Flourtown PA, US
Shiwei Tao - Hillsborough NJ, US
Hao Zhang - Belle Mead NJ, US
Suresh Dhanusu - Tamil Nadu, IN
Kumaravel Selvakumar - Bangalore, IN
Ramesh Babu Reddigunta - Chittoor District, IN
Steven J. Walker - Portage MI, US
Lawrence J. Kennedy - Titusville NJ, US
James R. Corte - Yardley PA, US
Tianan Fang - Newtown PA, US
Sutjano Jusuf - Princeton NJ, US
International Classification:
A61K 31/4192
C07D 401/14
C07D 249/06
A61K 31/27
A61K 31/454
C07D 401/04
Abstract:
The present invention provides compounds of Formula (I):or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Cyclohexyl Acid Triazole Azoles As Lpa Antagonists

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US Patent:
20210163470, Jun 3, 2021
Filed:
Dec 18, 2018
Appl. No.:
16/772842
Inventors:
- Princeton NJ, US
Peter Tai Wah Cheng - Princeton NJ, US
Ying Wang - Belle Mead NJ, US
Jun Li - Pittsburgh PA, US
Tianan Fang - Newtown PA, US
James R. Corte - Yardley PA, US
Jun Shi - Pennington NJ, US
Hao Zhang - Belle Mead NJ, US
Lawrence J. Kennedy - Titusville NJ, US
Shiwei Tao - Hillsborough NJ, US
International Classification:
C07D 417/14
C07D 401/14
C07D 413/14
C07D 403/14
Abstract:
The present invention provides compounds of Formula (I): Formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Cyclohexyl Acid Pyrazole Azoles As Lpa Antagonists

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US Patent:
20210078982, Mar 18, 2021
Filed:
Dec 18, 2018
Appl. No.:
16/954320
Inventors:
- Princeton NJ, US
Peter Tai Wah Cheng - Princeton NJ, US
Hao Zhang - Belle Mead NJ, US
Jun Li - Pittsburgh PA, US
Tianan Fang - Newtown PA, US
James R. Corte - Yardley PA, US
International Classification:
C07D 403/14
C07D 417/14
C07D 413/14
Abstract:
The present invention provides compounds of Formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Carbamoyloxymethyl Triazole Cyclohexyl Acids As Lpa Antagonists

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US Patent:
20200138789, May 7, 2020
Filed:
Jan 2, 2020
Appl. No.:
16/732387
Inventors:
- Princeton NJ, US
Jun Li - Pittsburgh PA, US
Jun Shi - Pennington NJ, US
Yan Shi - Flourtown PA, US
Shiwei Tao - Hillsborough NJ, US
Hao Zhang - Belle Mead NJ, US
Suresh Dhanusu - Hosur, IN
Kumaravel Selvakumar - Bangalore, IN
Ramesh Babu Reddigunta - Chittoor District, IN
Steven J Walker - Portage MI, US
Lawrence J. Kennedy - Titusville NJ, US
James R. Corte - Yardley PA, US
Tianan Fang - Newtown PA, US
Sutjano Jusuf - Princeton NJ, US
International Classification:
A61K 31/4192
C07D 401/14
C07D 249/06
A61K 31/27
A61K 31/454
C07D 401/04
Abstract:
The present invention provides compounds of Formula (I):or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.
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Tianan Fang from Newtown, PA, age ~57 Get Report