Inventors:
Ondrej Hendl - Portage MI, US
Susan Machkovech - Mattawan MI, US
Niki Waldron - Kalamazoo MI, US
Nancy Britten - Portage MI, US
Dannette Shaw - Hopkins MI, US
Alanta Lary - Kalamazoo MI, US
Thomas Yellig - Gobles MI, US
International Classification:
A61K039/12
A61K039/02
A61K035/78
US Classification:
424/204100, 424/234100, 424/093400, 424/093600, 424/776000
Abstract:
A composition comprising: (a) one to three bioactive agents; and (b) a vehicle comprising; (i) a modified liquid carrier, and (ii) an unmodified liquid carrier wherein the ratio by volume of the modified liquid carrier to the unmodified liquid carrier is between 0.00001:99.99999 to less than 0.01:99.99, that provide the composition with predictable sustained-release properties and wherein immediately after manufacture of the composition, said composition can be administered to a host such that the one to three bioactive agents is released to the host on a sustained basis.