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Thomas Tampone Phones & Addresses

  • Danbury, CT
  • 955 Georges Hill Rd, Southbury, CT 06488
  • 871 Elting Rd, Rosendale, NY 12472 (845) 658-8173

Work

Company: Boehringer ingelheim Mar 2009 Address: Ridgefield, CT Position: Process research scientist ii - department of chemical development

Education

Degree: Bachelor of Science (B.S.) School / High School: Western New England College 2002 to 2006 Specialities: Chemistry

Skills

Flow Chemistry • Process Chemistry • Organic Synthesis • Gmp • Nmr Spectroscopy • Hplc • Lc Ms • Gc Ms • Xrpd • Dsc • Tga • Microsoft Office

Industries

Pharmaceuticals

Resumes

Resumes

Thomas Tampone Photo 1

Senior Scientist

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Location:
955 Georges Hill Rd, Southbury, CT 06488
Industry:
Pharmaceuticals
Work:
Boehringer Ingelheim - Ridgefield, CT since Mar 2009
Process Research Scientist II - Department of Chemical Development

Boehringer Ingelheim Mar 2007 - Mar 2009
Process Research Scientist I - Department of Chemical Development

Boehringer Ingelheim Aug 2006 - Mar 2007
Research Associate
Education:
Western New England College 2002 - 2006
Bachelor of Science (B.S.), Chemistry
Skills:
Flow Chemistry
Process Chemistry
Organic Synthesis
Gmp
Nmr Spectroscopy
Hplc
Lc Ms
Gc Ms
Xrpd
Dsc
Tga
Microsoft Office

Publications

Us Patents

Piperidino-Dihydrothienopyrimidine Sulfoxides And Their Use For Treating Copd And Asthma

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US Patent:
8609670, Dec 17, 2013
Filed:
Aug 23, 2012
Appl. No.:
13/592664
Inventors:
Pascale A. J. Pouzet - Biberach an der Riss, DE
Peter Nickolaus - Warthausen, DE
Ulrike Werthmann - Biberach an der Riss, DE
Rogelio Perez Frutos - Sandy Hook CT, US
Soojin Kim - Demarest NJ, US
Jason Alan Mulder - New Milford CT, US
Nitinchandra D. Patel - Danbury CT, US
Thomas Gabriel Tampone - Southbury CT, US
Xudong Wei - Ridgefield CT, US
Assignee:
Boehringer Ingelheim International GmbH - Ingelheim am Rhein
International Classification:
A61K 31/519
US Classification:
5142601
Abstract:
The invention relates to novel piperidino-dihydrothienopyrimidine sulfoxides of formula I,.

Preparation Of Dihydrothieno [3, 2-D] Pyrimidines And Intermediates Used Therein

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US Patent:
20100222585, Sep 2, 2010
Filed:
Oct 15, 2008
Appl. No.:
12/738152
Inventors:
Rogelio Frutos - Sandy Hook CT, US
Jason Alan Mulder - New Milford CT, US
Sonia Rodriguez - New Milford CT, US
Chris Hugh Senanayake - Brookfield CT, US
Thomas G. Tampone - Southbury CT, US
Assignee:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH - Ingelheim am Rhein
International Classification:
C07D 491/04
US Classification:
544278
Abstract:
The invention relates to improved methods of preparing dihydrothienopyrimidines of formula 1, and intermediates thereof, (I) wherein X is SO or SO, preferably SO, and wherein R, R, R, R, Rand Rhave the meanings given in the description. The methods according to this invention are more suitable for large-scale synthesis of said pounds than prior methods because the new synthetic process avoids distillation and chromatographic purification between steps and results in a higher overall yield of the desired product.

Synthesis If Dihydrothieno[3,2-D]Pyrimidine Diols

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US Patent:
20110130563, Jun 2, 2011
Filed:
May 7, 2009
Appl. No.:
12/989575
Inventors:
Rogelio Perez Frutos - Sandy Hook CT, US
Thomas G. Tampone - Southbury CT, US
Jason Alan Mulder - New Milford CT, US
Chris Hugh Senanayake - Brookfield CT, US
Assignee:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH - Ingelheim am Rhein
International Classification:
C07D 239/00
US Classification:
544278
Abstract:
The present invention relates to an improved process for the preparation of dihydrothieno[3,2-d]pyrimidine diols, and similar pyrimidine diols, that is efficient, high-yielding, and does not require expensive and potentially unstable intermediates. The diols are used as intermediates in the synthesis of pyrimidine compounds which inhibit PDE4, and are thus useful in the treatment of respiratory or gastrointestinal diseases and complaints, peripheral or central nervous system diseases and disorders, inflammatory conditions, and cancers.

Novel Piperidino-Dihydrothienopyrimidine Sulfoxides And Their Use For Treating Copd And Asthma

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US Patent:
20130059866, Mar 7, 2013
Filed:
Feb 23, 2012
Appl. No.:
13/402996
Inventors:
Horst Dollinger - Schemmerhofen, DE
Rogelio Perez Frutos - Sandy Hook CT, US
Soojin Kim - Demarest NJ, US
Jason Alan Mulder - New Milford CT, US
Peter Nickolaus - Warthausen, DE
Nitinchandra D. Patel - Danbury CT, US
Pascale Pouzet - Biberach an der Riss, DE
Chris Hugh Senanayake - Brookfield CT, US
Thomas Gabriel Tampone - Southbury CT, US
Xudong Wei - Ridgefield CT, US
Ulrike Werthmann - Biberach an der Riss, DE
Assignee:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH - Ingelheim am Rhein
International Classification:
A61K 31/519
A61P 11/00
A61P 1/00
A61P 19/02
A61P 17/00
A61P 27/02
A61P 25/00
A61P 11/06
A61P 1/04
A61P 25/28
A61P 25/18
A61P 25/16
A61P 25/04
C07C 213/02
C07D 401/04
C07D 495/04
US Classification:
5142601, 544278, 564 1, 544333
Abstract:
The invention relates to novel piperidino-dihydrothienopyrimidine sulfoxides of formula I,

Continuous Process For Manufacturing Alkyl 7-Amino-5-Methyl-[1,2,5]Oxadiazolo[3,4-B]Pyridine-Carboxylate

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US Patent:
20210363157, Nov 25, 2021
Filed:
May 21, 2021
Appl. No.:
17/326383
Inventors:
- Ingelheim am Rhein, DE
Tobias ALT - Ingelheim am Rhein, DE
Andrew T. BRUSOE - New Milford CT, US
Frederic Gerard BUONO - Franklin Park NJ, US
Michael KLUMB - Mainz, DE
Bjoern STAHL - Ginsheim, DE
Thomas G. TAMPONE - Southbury CT, US
International Classification:
C07D 498/04
B01J 19/00
Abstract:
This invention relates to a novel continuous process for making alkyl 7-amino-5-methyl-[1,2,5]-oxadiazolo[3,4-b]pyridine-carboxylate.

Intermediate Compounds And Methods

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US Patent:
20210340101, Nov 4, 2021
Filed:
Jul 14, 2021
Appl. No.:
17/375322
Inventors:
- Ingelheim am Rhein, DE
Jason A. BRAZZILLO - Cortlandt Manor NY, US
Weitong DONG - Sandy Hook CT, US
Magnus ERIKSSON - Brookfield CT, US
Jon Charles LORENZ - New Milford CT, US
Laurence J. NUMMY - Newburgh NY, US
Sonia RODRIGUEZ - Avon CT, US
Jolaine SAVOIE - Sandy Hook CT, US
Kanwar Pal Singh SIDHU - Orange CT, US
Joshua D. SIEBER - Richmond VA, US
Thomas Gabriel TAMPONE - Southbury CT, US
Zhulin TAN - Cheshire CT, US
Jun WANG - New Milford CT, US
Li ZHANG - New Milford CT, US
Pengtao ZHANG - Pudong, CN
International Classification:
C07D 209/54
Abstract:
The present invention relates to compounds of (II) and an acceptable salt or hydrate thereof method of making same.

Intermediate Compounds And Methods

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US Patent:
20200369611, Nov 26, 2020
Filed:
Jul 30, 2018
Appl. No.:
16/635182
Inventors:
- Ingelheim am Rhein, DE
Jason A. BRAZZILLO - Cortlandt Manor NY, US
Magnus ERIKSSON - Brookfield CT, US
Jon Charles LORENZ - New Milford CT, US
Laurence J. NUMMY - Newburgh NY, US
Sonia RODRIGUEZ - New Milford CT, US
Jolaine SAVOIE - Sandy Hook CT, US
Kanwar Pal Singh SIDHU - Orange CT, US
Joshua D. SIEBER - Sandy Hook CT, US
Thomas Gabriel TAMPONE - Southbury CT, US
Zhulin TAN - Cheshire CT, US
June WANG - New Milford CT, US
Li ZHANG - New Milford CT, US
International Classification:
C07D 209/54
Abstract:
The present invention relates to compounds of (II) and an acceptable salt or hydrate thereof method of making same.

Novel Piperidino-Dihydrothienopyrimidine Sulfoxides And Their Use For Treating Copd And Asthma

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US Patent:
20200048278, Feb 13, 2020
Filed:
Oct 11, 2019
Appl. No.:
16/599209
Inventors:
- Ingelheim am Rhein, DE
Peter NICKOLAUS - Warthausen, DE
Ulrike WERTHMANN - Biberach an der Riss, DE
Rogelio P. FRUTOS - Sandy Hook CT, US
Soojin KIM - Seoul, KR
Jason Alan MULDER - New Milford CT, US
Nitinchandra D. PATEL - Danbury CT, US
Chris Hugh SENANAYAKE - Brookfield CT, US
Thomas Gabriel TAMPONE - Southbury CT, US
Xudong WEI - Coventry RI, US
International Classification:
C07D 495/04
Abstract:
Piperidino-dihydrothienopyrimidine sulfoxides of formula Iwherein:
Thomas G Tampone from Danbury, CT, age ~40 Get Report