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Tapas Gupta Phones & Addresses

  • River Forest, IL

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Us Patents

Compositions And Methods For Treating Malaria With Cupredoxin And Cytochrome

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US Patent:
7338766, Mar 4, 2008
Filed:
May 19, 2006
Appl. No.:
11/436590
Inventors:
Ananda Chakrabarty - Villa Park IL, US
Tapas Das Gupta - River Forest IL, US
Tohru Yamada - Oak Park IL, US
Anita Chaudhari - Clifton Park NY, US
Arsenio Fialho - Lisbon, PT
Chang Soo Hong - Chicago IL, US
Assignee:
The Board of Trustees of the University of Illinois - Urbana IL
International Classification:
C12Q 1/68
C12P 21/04
A61K 38/00
A61K 38/44
C07K 14/445
US Classification:
435 6, 435 697, 4352581, 4352582, 4241851, 424 944, 514 2, 514 12, 530300, 530350
Abstract:
The present invention relates to cupredoxin and cytochrome and their use, separately or together, to inhibit the spread of parasitemia in mammalian red blood cells and other tissues infected by the malaria parasite, and in particular the parasitemia of human red blood cells by. The invention provides isolated peptides that are variants, derivatives or structural equivalents of cupredoxins or cytochrome c, and compositions comprising cupredoxins and/or cytochrome c, or variants, derivatives or structural equivalents thereof, that are useful for treating or preventing malaria infection in mammals. Further, the invention provides methods to treat mammalian patients to prevent or inhibit the growth of malarial infection in mammals. The invention also provides methods to prevent the growth of malaria infection in insect vectors.

Compositions And Methods For Treating Conditions Related To Ephrin Signaling With Cupredoxins

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US Patent:
7381701, Jun 3, 2008
Filed:
May 19, 2006
Appl. No.:
11/436592
Inventors:
Ananda Chakrabarty - Villa Park IL, US
Tapas Das Gupta - River Forest IL, US
Tohru Yamada - Oak Park IL, US
Anita Chaudhari - Clifton Park NY, US
Arsenio Fialho - Lisbon, PT
Yonghua Zhu - Chicago IL, US
Assignee:
The Borad of Trustees of the University of Illinois - Urbana IL
International Classification:
A61K 38/00
C07K 7/00
C07K 14/00
US Classification:
514 2, 530324, 530326
Abstract:
The present invention relates to compositions and methods of use of cupredoxins, and variants, derivatives and structural equivalents of cupredoxins that interfere with the ephrin signaling system in mammalian cells. Specifically, the invention relates to compositions and methods that use cupredoxins, such as azurin, rusticyanin and plastocyanin, and variants, derivatives and structural equivalents thereof, to treat cancer in mammals.

Compositions And Methods For Treating Hiv Infection With Cupredoxin And Cytochrome C

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US Patent:
7511117, Mar 31, 2009
Filed:
Nov 20, 2007
Appl. No.:
11/943034
Inventors:
Ananda Chakrabarty - Villa Park IL, US
Tapas Das Gupta - River Forest IL, US
Tohru Yamada - Oak Park IL, US
Anita Chaudhari - Clifton Park NY, US
Arsenio Fialho - Lisbon, PT
Chang Soo Hong - Chicago IL, US
Assignee:
The Board of Trustees of the University of Illinois - Urbana IL
International Classification:
C07K 5/00
US Classification:
530300
Abstract:
The present invention relates to cupredoxin, specifically azurin, and/or cytochrome cand their use in inhibiting of viral infection, and in particular infection of mammalian cells by the Human Immunodeficiency Virus (HIV). The invention also relates to variants and derivatives of cupredoxin and cytochrome c that retain the ability to inhibit viral infection, and in particular infection by the Human Immunodeficiency Virus (HIV). The invention also relates to research methods for studying viral and bacterial infection in mammalian cells.

Compositions And Methods To Prevent Cancer With Cupredoxins

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US Patent:
7618939, Nov 17, 2009
Filed:
Sep 13, 2007
Appl. No.:
11/854654
Inventors:
Tapas Das Gupta - River Forest IL, US
Ananda Chakrabarty - Villa Park IL, US
Assignee:
The Board of Trustees of the University of Illinois - Urbana IL
International Classification:
C07K 14/00
US Classification:
514 2, 530300
Abstract:
The present invention relates to compositions comprising peptides that may be variants, derivatives and structural equivalents of cupredoxins that inhibit the development of premalignant lesions in mammalian cells, tissues and animals. Specifically, these compositions may comprise azurin from , and/or the 50-77 residue region of azurin (p28). The present invention further relates to compositions that may comprise cupredoxin(s), and/or variants, derivatives or structural equivalents of cupredoxins, that retain the ability to inhibit the development of premalignant lesions in mammalian cells, tissues or animals. These compositions may be peptides or pharmaceutical compositions, among others. The compositions of the invention may be used to prevent the development of premalignant lesions in mammalian cells, tissues and animals, and thus prevent cancer.

Cupredoxin Derived Transport Agents And Methods Of Use Thereof

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US Patent:
7691383, Apr 6, 2010
Filed:
Oct 6, 2005
Appl. No.:
11/244105
Inventors:
Ananda Chakrabarty - Villa Park IL, US
Tapas Das Gupta - River Forest IL, US
Tohru Yamada - Oak Park IL, US
Arsenio Fialho - Lisbon, PT
Assignee:
The Board of Trustees of the University of Illinois - Urbana IL
International Classification:
A61K 39/00
A61K 49/00
A61K 39/10
US Classification:
4241851, 424 91, 424 92, 4241841, 4241901, 4241921, 4242341, 4242501, 4242531, 4242601, 530300, 530350, 536 231, 536 237
Abstract:
The present invention discloses methods and materials for delivering a cargo compound into a cancer cell. Delivery of the cargo compound is accomplished by the use of protein transduction domains derived from cupredoxins. The invention further discloses methods for treating cancer and diagnosing cancer.

Compositions And Methods For Treating Malaria With Cupredoxin And Cytochrome

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US Patent:
7740857, Jun 22, 2010
Filed:
Mar 3, 2008
Appl. No.:
12/041411
Inventors:
Ananda Chakrabarty - Villa Park IL, US
Tapas Das Gupta - River Forest IL, US
Tohru Yamada - Oak Park IL, US
Anita Chaudhari - Clifton Park NY, US
Arsenio Fialho - Lisbon, PT
Chang Soo Hong - Chicago IL, US
Assignee:
The Board of Trustees of the University of Illinois - Urbana IL
International Classification:
A61K 39/00
A61K 38/44
C12P 21/04
C07K 14/445
US Classification:
4241851, 424 944, 435 697, 4352581, 530300, 514 12
Abstract:
The present invention relates to cupredoxin and cytochrome and their use, separately or together, to inhibit the spread of parasitemia in mammalian red blood cells and other tissues infected by the malaria parasite, and in particular the parasitemia of human red blood cells by. The invention provides isolated peptides that are variants, derivatives or structural equivalents of cupredoxins or cytochrome c, and compositions comprising cupredoxins and/or cytochrome c, or variants, derivatives or structural equivalents thereof, that are useful for treating or preventing malaria infection in mammals. Further, the invention provides methods to treat mammalian patients to prevent or inhibit the growth of malarial infection in mammals. The invention also provides methods to prevent the growth of malaria infection in insect vectors.

Compositions And Methods For Treating Hiv Infection With Cupredoxin And Cytochrome C

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US Patent:
7795410, Sep 14, 2010
Filed:
Mar 5, 2009
Appl. No.:
12/398708
Inventors:
Ananda Chakrabarty - Villa Park IL, US
Tapas Das Gupta - River Forest IL, US
Tohru Yamada - Oak Park IL, US
Anita Chaudhari - Clifton Park NY, US
Arsenio Fialho - Lisbon, PT
Chang Soo Hong - Chicago IL, US
Assignee:
The Board of Trustees of the University of Illinois - Urbana IL
International Classification:
C07H 21/02
C12N 15/63
US Classification:
536 231, 4353201
Abstract:
The present invention relates to cupredoxin, specifically azurin, and/or cytochrome cand their use in inhibiting of viral infection, and in particular infection of mammalian cells by the Human Immunodeficiency Virus (HIV). The invention also relates to variants and derivatives of cupredoxin and cytochrome c that retain the ability to inhibit viral infection, and in particular infection by the Human Immunodeficiency Virus (HIV). The invention also relates to research methods for studying viral and bacterial infection in mammalian cells.

Compositions And Methods To Treat Cancer With Cupredoxins And Cpg Rich Dna

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US Patent:
8017749, Sep 13, 2011
Filed:
Dec 4, 2007
Appl. No.:
11/950165
Inventors:
Tapas Das Gupta - River Forest IL, US
Ananda Chakrabarty - Villa Park IL, US
Assignee:
The Board of Trustees of the University of Illinois - Urbana IL
International Classification:
A61K 39/00
A61K 39/38
A61K 39/02
A61K 39/108
A61K 48/00
A01N 37/18
A61P 31/04
US Classification:
536 231, 4241841, 4241851, 4242341, 4242601, 514 11, 514 24, 514 44 R
Abstract:
The present invention relates to compositions comprising CpG rich DNA from. The compositions optionally comprise a cupredoxin. The present invention includes specific CpG DNAs from that are useful for treating cancer and other conditions in patients. These compositions are optionally in a pharmaceutically acceptable carrier and also optionally comprise a cupredoxin. The present invention further relates to methods to express proteins near cancer cells. These methods may be used to express therapeutic or diagnostic proteins near cancer cells in a patient suffering from cancer or other conditions, and can also be used for diagnosing cancer in a patient. This method uses the gene for azurin from as an expression system for azurin or heterologous proteins in or heterologous cells.
Tapas K Gupta from River Forest, ILDeceased Get Report