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Sumith A Kularatne

from West Lafayette, IN
Age ~51
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Also known as:
Sumith F, Sumith E
Phone and address:
3340 Webster St, Lafayette, IN 47906
Related to:
Kularatne Sumith, 51Sepalika W Kularatne, 52
Connected to:
Aaron R Kulas, 44Andreas A Kulas, 60Dennis Kulas, 84Gary B Kulas, 60Katarzyna J Kulas, 44Lauren Kulas, 37Lawrence A Kulas, 95Andrew N Kulasekara, 62Damian Kulash, 49Joan R Kulash, 76

Sumith Kularatne Phones & Addresses

  • 3340 Webster St, W Lafayette, IN 47906
  • West Lafayette, IN
  • San Diego, CA
  • 1740 Hillside St, Wichita, KS 67214
  • 1945 N Rock Rd, Wichita, KS 67206
  • Indianapolis, IN
  • W Lafayette, IN

Resumes

Resumes

Sumith Kularatne Photo 1

Executive Vice President Of R And D

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Location:
West Lafayette, IN
Industry:
Biotechnology
Work:
On Target Laboratories, Llc Mar 2012 - Jan 2017
Vice President of R and D
On Target Laboratories, Llc Mar 2012 - Jan 2017
Executive Vice President of R and D
The Scripps Research Institute Dec 2009 - Feb 2012
Postdoctoral Fellow
Phaserx 2010 - 2010
Consultant
Merck 2007 - 2009
Collaborator
Education:
Scripps Research 2009 - 2012
Scripps Research 2009 - 2011
Purdue University 2005 - 2009
Skills:
Cell Culture
In Vitro
Protein Chemistry
Cancer
Organic Synthesis
Cell
Antibodies
Molecular Biology
Drug Design
In Vivo
Flow Cytometry
Clinical Development
Drug Delivery
Stem Cells
Circulating Tumor Cells
Small Molecule Drug Conjugates
Antibody Drug Conjugates
Antibody Dependent Cell Mediated Cytotoxicity
Cancer Biology
Immunotherapy
Animal Studies
Radioimaging
Optical Imaging
Sumith Kularatne Photo 2

Sumith Kularatne

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Location:
United States

Publications

Us Patents

Composition And Method For Treating Inflammatory Disease

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US Patent:
20090012009, Jan 8, 2009
Filed:
May 30, 2008
Appl. No.:
12/130121
Inventors:
Philip S. Low - West Lafayette IN, US
Sumith A. Kularatne - West Lafayette IN, US
International Classification:
A61K 38/05
A61K 31/519
A61P 29/00
US Classification:
514 19, 514249
Abstract:
A method of treating inflammatory diseases, and compositions and compounds therefor are described. More particularly, a method of treating inflammatory disease states with vitamin-hapten conjugates is described.

Ex Vivo Flow Cytometry Method And Device

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US Patent:
20100055735, Mar 4, 2010
Filed:
Nov 2, 2007
Appl. No.:
12/513028
Inventors:
Philip Stewart Low - West Lafayette IN, US
Wei He - West Lafayette IN, US
Sumith A. Kularatne - West Lafayette IN, US
International Classification:
C12Q 1/06
US Classification:
435 39
Abstract:
The invention relates to a method for diagnosing a disease state mediated by pathogenic cells. The method comprises the steps of combining with an ex vivo patient sample a composition comprising a conjugate or complex of the general formulawherein the group Acomprises a ligand that binds to the pathogenic cells and the group X comprises an imaging agent, and detecting the pathogenic cells that express a receptor for the ligand using flow cytometry.

Positron Emission Tomography Imaging Method

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US Patent:
20100322854, Dec 23, 2010
Filed:
Feb 7, 2008
Appl. No.:
12/526096
Inventors:
Philip Stewart Low - West Lafayette IN, US
Sumith K. Kularatne - West Lafayette IN, US
Assignee:
PURDUE RESEARCH FOUNDATION - West Lafayette IN
International Classification:
A61K 51/04
C07D 207/50
A61P 43/00
US Classification:
424 165, 544258
Abstract:
Described herein are compositions and methods for diagnosing and/or monitoring pathogenic disease states using positron emission tomography, wherein the pathogenic cells uniquely express, preferentially express, or overexpress vitamin receptors. Also described herein are F conjugates of vitamins and vitamin receptor-binding analogs and derivatives.

Psma Binding Ligand-Linker Conjugates And Methods For Using

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US Patent:
20100324008, Dec 23, 2010
Filed:
Aug 15, 2008
Appl. No.:
12/673931
Inventors:
Philip Stewart Low - West Lafayette IN, US
Sumith A. Kularatne - San Diego CA, US
Assignee:
PURDUE RESEARCH FOUNDATION - West Lafayette IN
International Classification:
A61K 31/555
C07K 2/00
C07C 275/00
C07C 237/00
C07F 3/10
US Classification:
514184, 530300, 564 32, 564159, 548404
Abstract:
Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.

Psma Binding Ligand-Linker Conjugates And Methods For Using

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US Patent:
20110288152, Nov 24, 2011
Filed:
Oct 16, 2009
Appl. No.:
13/124448
Inventors:
Philip Stewart Low - West Lafayette IN, US
Sumith A. Kularatne - San Diego CA, US
Assignee:
Purdue Research Foundation - West Lafayette IN
International Classification:
A61K 31/7088
A61P 35/00
C07K 2/00
A61K 31/713
C07H 21/04
C07H 21/02
US Classification:
514 44 A, 536 231, 536 245, 530322, 514 44 R
Abstract:
Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for targeting prostate cancer cells. Also described herein are compositions containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.

Psma Binding Ligand-Linker Conjugates And Methods For Using

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US Patent:
20140073763, Mar 13, 2014
Filed:
Mar 14, 2013
Appl. No.:
13/826079
Inventors:
Purdue Research Foundation - , US
Sumith A. KULARATNE - West Lafayette IN, US
Assignee:
PURDUE RESEARCH FOUNDATION - WEST LAFAYETTE IN
International Classification:
C07K 5/08
US Classification:
530331
Abstract:
Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.

Psma Binding Ligand-Linker Conjugates And Methods For Using

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US Patent:
20230000836, Jan 5, 2023
Filed:
Jan 11, 2022
Appl. No.:
17/573304
Inventors:
- West Lafayette IN, US
Sumith A. Kularatne - West Lafayette IN, US
International Classification:
A61K 31/426
C07C 323/52
C07D 207/416
A61K 47/54
A61K 49/00
A61K 51/04
C07K 5/08
A61K 31/4745
A61K 31/475
A61K 51/08
A61K 47/64
Abstract:
Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.

Psma Binding Ligand-Linker Conjugates And Methods For Using

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US Patent:
20210338641, Nov 4, 2021
Filed:
Jun 25, 2021
Appl. No.:
17/359277
Inventors:
- West Lafayette IN, US
Sumith A. Kularatne - West Lafayette IN, US
International Classification:
A61K 31/426
C07C 323/52
C07D 207/416
A61K 47/54
A61K 49/00
A61K 51/04
C07K 5/08
A61K 31/4745
A61K 31/475
A61K 51/08
A61K 47/64
Abstract:
Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.
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Sumith A Kularatne from West Lafayette, IN, age ~51 Get Report