US Patent:
20230022117, Jan 26, 2023
Inventors:
- CHARLESTON SC, US
Suhua SHA - Mt. Pleasant SC, US
International Classification:
C12N 15/113
A61P 27/16
Abstract:
Described herein are compositions capable of targeting CaMKKβ and/or AMPK alpha and formulations thereof. Also described herein are methods of using the compositions and formulations thereof. In some embodiments, the compositions capable of targeting CaMKKβ and/or AMPK alpha and formulations thereof can prevent or treat outer hair cell loss, such as that which can occur as a result of auditory or chemical insult. In some embodiments, the compositions capable of targeting CaMKKβ and/or AMPK alpha and formulations thereof can treat or prevent acquired hearing loss.