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Sheela Muley

from Fremont, CA
Age ~51

Sheela Muley Phones & Addresses

  • 5884 Northland Ter, Fremont, CA 94555 (510) 744-0113
  • 775 Longfellow Dr, Fremont, CA 94539 (510) 364-2497
  • Sunnyvale, CA
  • Santa Clara, CA
  • Belmont, CA
  • Alameda, CA

Work

Company: Intrexon corporation 2011 Position: Sr. scientist

Education

Degree: MS School / High School: San Jose State University 1996 to 1999 Specialities: Chemistry

Skills

Hplc • Sds Page • Protein Purification • Lims • Analytical Chemistry • Uv Vis • Western Blotting • Sop • Assay Development • High Throughput Screening • Uv/Vis • Lifesciences • Enzyme Assays • Protein Chemistry • Gas Chromatography • Chemistry • Life Sciences • Validation • Uv/Vis Spectroscopy • Technology Transfer • Biofuels • Standard Operating Procedure • Purification • Laboratory Information Management System • Chromatography • Microsoft Office • High Performance Liquid Chromatography

Languages

English

Industries

Biotechnology

Resumes

Resumes

Sheela Muley Photo 1

Director, Assay And Analytics

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Location:
775 Longfellow Dr, Fremont, CA 94539
Industry:
Biotechnology
Work:
Intrexon Corporation since 2011
Sr. Scientist

Amyris Biotechnologies Aug 2008 - Jul 2010
Scientist

Theranos May 2008 - Jul 2008
Senior Scientist - Development Group

Codexis Jun 2006 - Apr 2008
Staff Scientist - Analytical Biochemistry Department

Codexis Jun 2004 - Jun 2006
Research Associate II- Analytical Biochemistry Department
Education:
San Jose State University 1996 - 1999
MS, Chemistry
Nizam's Institute of Medical Sciences 1993 - 1995
Diploma, Transfusion Medicine Technology
St.Ann's College for Women 1990 - 1993
B.Sc, Botany, Zoology, Chemistry
Skills:
Hplc
Sds Page
Protein Purification
Lims
Analytical Chemistry
Uv Vis
Western Blotting
Sop
Assay Development
High Throughput Screening
Uv/Vis
Lifesciences
Enzyme Assays
Protein Chemistry
Gas Chromatography
Chemistry
Life Sciences
Validation
Uv/Vis Spectroscopy
Technology Transfer
Biofuels
Standard Operating Procedure
Purification
Laboratory Information Management System
Chromatography
Microsoft Office
High Performance Liquid Chromatography
Languages:
English

Publications

Us Patents

Biocatalytic Processes For The Preparation Of Stereomerically Pure Fused Bicyclic Proline Compounds

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US Patent:
8574876, Nov 5, 2013
Filed:
Mar 30, 2012
Appl. No.:
13/436506
Inventors:
Benjamin Mijts - Belmont CA, US
Sheela Muley - Fremont CA, US
Jack Liang - San Mateo CA, US
Lisa M. Newman - San Jose CA, US
Xiyun Zhang - Fremont CA, US
James Lalonde - Palo Alto CA, US
Michael D. Clay - Menlo Park CA, US
Jun Zhu - Shanghai, CN
John M. Gruber - El Dorado Hills CA, US
Jeffrey Colbeck - Menlo Park CA, US
Jagadeesh Mavinahalli - Singapore, SG
Roger Sheldon - Hoog Keppel, NL
Assignee:
Codexis, Inc. - Redwood City CA
International Classification:
C12P 7/62
C12P 13/22
US Classification:
435135, 435108
Abstract:
The present disclosure provides substantially enantiomerically pure heterobicyclic compounds of the following structural formulas,.

Biocatalytic Processes For The Preparation Of Substantially Stereomerically Pure Fused Bicyclic Proline Compounds

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US Patent:
20100063300, Mar 11, 2010
Filed:
Jun 23, 2009
Appl. No.:
12/490190
Inventors:
Benjamin Mijts - Belmont CA, US
Sheela Muley - Fremont CA, US
Jack Liang - San Mateo CA, US
Lisa M. Newman - San Jose CA, US
Xiyun Zhang - Fremont CA, US
James Lalonde - Palo Alto CA, US
Michael D. Clay - Menlo Park CA, US
Jun Zhu - Sunnyvale CA, US
John M. Gruber - El Dorado Hills CA, US
Jeffrey Colbeck - Menlo Park CA, US
Jagadeesh Mavinahalli - Singapore, SG
Roger Sheldon - Hoog Keppel, NL
Assignee:
Codexis, Inc. - Redwood City CA
International Classification:
C07D 209/52
US Classification:
548452
Abstract:
The present disclosure provides substantially enantiomerically pure heterobicyclic compounds of the following structural formulas,wherein A, M, M′, and Rare as described herein, and to biocatalytic processes for their preparation, and to the enzymes used in those processes.

Stereomerically Pure Fused Bicyclic Proline Compounds Useful For Preparing Hepatitis C Protease Inhibitors

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US Patent:
20120130087, May 24, 2012
Filed:
Nov 11, 2011
Appl. No.:
13/294930
Inventors:
Benjamin Mijts - Belmont CA, US
Sheela Muley - Fremont CA, US
Jack Liang - San Mateo CA, US
Lisa M. Newman - San Jose CA, US
Xiyun Zhang - Fremont CA, US
James Lalonde - Palo Alto CA, US
Michael D. Clay - Menlo Park CA, US
Jun Zhu - Shanghai, CN
John M. Gruber - El Dorado Hills CA, US
Jeffrey Colbeck - Menlo Park CA, US
Jagadeesh Mavinahalli - Singapore, SG
Roger Sheldon - Hoog Keppel, NL
Assignee:
CODEXIS, INC. - Redwood City CA
International Classification:
C07D 209/52
C07D 487/14
US Classification:
548418, 548512, 548452
Abstract:
The present disclosure provides substantially enantiomerically pure heterobicyclic compounds of the following structural formulas,wherein A, M, M′, and Rare as described herein, and to biocatalytic processes for their preparation, and to the enzymes used in those processes.

Lantibiotic Variants And Uses Thereof

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US Patent:
20190315814, Oct 17, 2019
Filed:
Jul 14, 2017
Appl. No.:
16/316328
Inventors:
- Blacksburg VA, US
Johan Anthony KERS - Wellesley MA, US
Sheela MULEY - Fremont CA, US
Melissa MAYO - Foster City CA, US
Jeffrey COLBECK - Belmont CA, US
Robert Eryl SHARP - Belmont CA, US
Anthony W. DEFUSCO - Newberry FL, US
International Classification:
C07K 14/315
A61K 45/06
A61K 38/16
A61K 9/68
A61Q 11/00
A61K 9/00
A01N 63/02
A61P 31/04
A61K 8/64
Abstract:
The disclosure relates to lantibiotic structural variants that have improved antimicrobial properties when compared to wild-type lantibiotics, and uses thereof. Embodiments include non-naturally occurring lantibiotics.

Biological Production Of Multi-Carbon Compounds From Methane

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US Patent:
20170335351, Nov 23, 2017
Filed:
Jul 13, 2017
Appl. No.:
15/648920
Inventors:
- Blacksburg VA, US
Genevieve M. Vidanes - San Francisco CA, US
Guillaume Cottarel - Mountain View CA, US
Sheela Muley - Fremont CA, US
Roy Kamimura - Daly City CA, US
Akbar F. Javan - Chapel Hill NC, US
Jianping Sun - Belmont CA, US
Eli S. Groban - San Francisco CA, US
Assignee:
INTREXON CORPORATION - Blacksburg VA
International Classification:
C12P 7/16
C12N 9/10
C12N 9/88
C12N 9/04
C12N 15/52
Abstract:
Multi-carbon compounds such as ethanol, n-butanol, sec-butanol, isobutanol, tert-butanol, fatty (or aliphatic long chain) alcohols, fatty acid methyl esters, 2,3-butanediol and the like, are important industrial commodity chemicals with a variety of applications. The present invention provides metabolically engineered host microorganisms which metabolize methane (CH) as their sole carbon source to produce multi-carbon compounds for use in fuels (e.g., bio-fuel, bio-diesel) and bio-based chemicals. Furthermore, use of the metabolically engineered host microorganisms of the invention (which utilize methane as the sole carbon source) mitigate current industry practices and methods of producing multi-carbon compounds from petroleum or petroleum-derived feedstocks, and ameliorate much of the ongoing depletion of arable food source “farmland” currently being diverted to grow bio-fuel feedstocks, and as such, improve the environmental footprint of future bio-fuel, bio-diesel and bio-based chemical compositions.

Biological Production Of Multi-Carbon Compounds From Methane

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US Patent:
20170152529, Jun 1, 2017
Filed:
Jun 24, 2016
Appl. No.:
15/192290
Inventors:
- Blacksburg VA, US
Genevieve M. Vidanes - San Francisco CA, US
Guillaume Cottarel - Mountain View CA, US
Sheela Muley - Fremont CA, US
Roy Kamimura - Daly City CA, US
Akbar F. Javan - Chapel Hill NC, US
Jianping Sun - Belmont CA, US
Eli S. Groban - San Francisco CA, US
Assignee:
INTREXON CORPORATION - Blacksburg VA
International Classification:
C12P 7/16
C12N 15/52
C12N 9/88
C12N 9/04
C12N 9/10
Abstract:
Multi-carbon compounds such as ethanol, n-butanol, sec-butanol, isobutanol, tert-butanol, fatty (or aliphatic long chain) alcohols, fatty acid methyl esters, 2,3-butanediol and the like, are important industrial commodity chemicals with a variety of applications. The present invention provides metabolically engineered host microorganisms which metabolize methane (CH) as their sole carbon source to produce multi-carbon compounds for use in fuels (e.g., bio-fuel, bio-diesel) and bio-based chemicals. Furthermore, use of the metabolically engineered host microorganisms of the invention (which utilize methane as the sole carbon source) mitigate current industry practices and methods of producing multi-carbon compounds from petroleum or petroleum-derived feedstocks, and ameliorate much of the ongoing depletion of arable food source “farmland” currently being diverted to grow bio-fuel feedstocks, and as such, improve the environmental footprint of future bio-fuel, bio-diesel and bio-based chemical compositions.

Biological Production Of Multi-Carbon Compounds From Methane

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US Patent:
20160160243, Jun 9, 2016
Filed:
Jan 7, 2016
Appl. No.:
14/989859
Inventors:
- Blacksburg VA, US
Genevieve M. Vidanes - San Francisco CA, US
Guillaume Cottarel - Mountain View CA, US
Sheela Muley - Fremont CA, US
Roy Kamimura - Daly City CA, US
Akbar F. Javan - Chapel Hill NC, US
Jianping Sun - Belmont CA, US
Eli S. Groban - San Francisco CA, US
Assignee:
Intrexon Corporation - Blacksburg VA
International Classification:
C12P 7/16
C12N 9/04
C12N 9/88
C12N 9/10
Abstract:
Multi-carbon compounds such as ethanol, n-butanol, sec-butanol, isobutanol, tert-butanol, fatty (or aliphatic long chain) alcohols, fatty acid methyl esters, 2,3-butanediol and the like, are important industrial commodity chemicals with a variety of applications. The present invention provides metabolically engineered host microorganisms which metabolize methane (CH) as their sole carbon source to produce multi-carbon compounds for use in fuels (e.g., bio-fuel, bio-diesel) and bio-based chemicals. Furthermore, use of the metabolically engineered host microorganisms of the invention (which utilize methane as the sole carbon source) mitigate current industry practices and methods of producing multi-carbon compounds from petroleum or petroleum-derived feedstocks, and ameliorate much of the ongoing depletion of arable food source “farmland” currently being diverted to grow bio-fuel feedstocks, and as such, improve the environmental footprint of future bio-fuel, bio-diesel and bio-based chemical compositions.

Biological Conversion Of Multi-Carbon Compounds From Methane

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US Patent:
20140273128, Sep 18, 2014
Filed:
Mar 12, 2014
Appl. No.:
14/206835
Inventors:
- Blacksburg VA, US
Genevieve M. VIDANES - San Francisco CA, US
Guillaume COTTAREL - Mountain View CA, US
Sheela MULEY - Fremont CA, US
Roy KAMIMURA - Daly City CA, US
Akbar F. JAVAN - Chapel Hill NC, US
Jianping SUN - Belmont CA, US
Eli S. GROBAN - San Francisco CA, US
Assignee:
Intrexon Corporation - Blacksburg VA
International Classification:
C12P 7/16
C12N 15/74
US Classification:
435160, 435157, 4352523
Abstract:
Multi-carbon compounds such as ethanol, n-butanol, sec-butanol, isobutanol, tert-butanol, fatty (or aliphatic long chain) alcohols, fatty acid methyl esters, 2,3-butanediol and the like, are important industrial commodity chemicals with a variety of applications. The present invention provides metabolically engineered host microorganisms which metabolize methane (CH) as their sole carbon source to produce multi-carbon compounds for use in fuels (e.g., bio-fuel, bio-diesel) and bio-based chemicals. Furthermore, use of the metabolically engineered host microorganisms of the invention (which utilize methane as the sole carbon source) mitigate current industry practices and methods of producing multi-carbon compounds from petroleum or petroleum-derived feedstocks, and ameliorate much of the ongoing depletion of arable food source “farmland” currently being diverted to grow bio-fuel feedstocks, and as such, improve the environmental footprint of future bio-fuel, bio-diesel and bio-based chemical compositions.
Sheela Muley from Fremont, CA, age ~51 Get Report