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Sachiko Hirosue

from Brooklyn, NY
Age ~53
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Related to:
Keiko Hirosue KorolevSerge V Korolev, 67Ilya S Korolev, 46Petr S Korolev, 44Keiko C V, 44
Connected to:
Bryan A Hirota, 54Luther L Hirota, 71Ryan K Hirota, 71Lisa H Hirotani, 63Maki Hirotani, 55Mitsuru Hirotani, 60Paul E Hiroto, 65Stephanie M Hirotsu, 49Ramesh R Hirpara, 54Sanjaykumar S Hirpara, 53

Sachiko Hirosue Phones & Addresses

  • Brooklyn, NY
  • Astoria, NY
  • 115 102Nd St, New York, NY 10029 (212) 410-6496
  • 538 Franklin St, Cambridge, MA 02139 (617) 497-8431
  • Baltimore, MD
  • Newton, MA

Publications

Us Patents

Sub-100Nm Biodegradable Polymer Spheres Capable Of Transporting And Releasing Nucleic Acids

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US Patent:
62548905, Jul 3, 2001
Filed:
Dec 10, 1998
Appl. No.:
9/209031
Inventors:
Sachiko Hirosue - Cambridge MA
Bernhard G. Mueller - Kaltbach, CH
Robert S. Langer - Newton MA
Richard C. Mulligan - Lincoln MA
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61K 951
A61K 952
A61K 964
A61K 958
US Classification:
424490
Abstract:
The present invention provides biodegradable polymer nanospheres capable of transporting and releasing therapeutic agents, specifically nucleic acids. In preferred embodiments, a sub-150 nm nanosphere is formed containing nucleic acids. Thereafter, the agent is released from the nanosphere. In one embodiment a biodegradable polymer nanosphere surface has attached to it a targeting moiety. In another embodiment, the biodegradable polymer nanosphere surface has attached to it a masking moiety. In yet another embodiment both targeting and masking moieties are attached to the nanosphere surface.
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Sachiko Hirosue from Brooklyn, NY, age ~53 Get Report