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Ronald D Poretz

from Lake Worth, FL
Age ~85
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Also known as:
Ronald Dr Poretz, Ronald David Poretz, Ronald J Poretz, Ronald N Poretz, Ron D Poretz, Ronald D Porete, Ronald D Portez
Phone and address:
610 Atlantis Estates Way, Lake Worth, FL 33462
Related to:
Alexi M PoretzNorma J Poretz, 82
Connected to:
Joseph M Porey, 44Domenick A Porfidia, 60Jean F Porfido, 81Lorraine W Porfido, 79Leanne S Porfilio, 67Lynne T Porfiri, 64Michael A Porfirio, 80Rafael L Porfirio, 48Vance A Porfirio, 71Arnold B Porges, 92

Ronald Poretz Phones & Addresses

  • 610 Atlantis Estates Way, Lake Worth, FL 33462
  • Atlantis, FL
  • 8 York Rd, Marlboro, NJ 07746 (732) 536-6894

Publications

Us Patents

Method For Detecting A Predisposition To Susceptibility To Toxic Effects Of Drugs And Poisons

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US Patent:
59357908, Aug 10, 1999
Filed:
Aug 5, 1997
Appl. No.:
8/910443
Inventors:
Ronald D. Poretz - Marlboro NJ
Paul Manowitz - East Brunswick NJ
Assignee:
Rutgers, The State University of New Jersey - Piscataway NJ
University of Medicine and Dentistry of New Jersey - Piscataway NJ
International Classification:
C12Q 168
US Classification:
435 6
Abstract:
The present invention relates to methods for diagnosis of susceptibility to neurotoxicity or the pathological effects of neurotoxicity based on detection of a genetic marker in an individual. The present invention is directed generally to methods and associated compositions and kits for detecting the presence of arylsulfatase A (ASA) pseudodeficiency (PD) mutations in humans. Detection of these mutations has been surprisingly found to be a strong indicator for susceptibility to neurotoxicity and/or susceptibility to toxicant's pathological effects, as well as an important marker in evaluating the likelihood of metachromatic leukodystrophy (MLD).

Marker For Individuals Susceptible To Alcoholism

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US Patent:
57363250, Apr 7, 1998
Filed:
Aug 31, 1994
Appl. No.:
8/299187
Inventors:
Paul Manowitz - East Brunswick NJ
Ronald D. Poretz - Marlboro NJ
David Park - New York NY
Michael Ricketts - Somerset NJ
Assignee:
Algene LLC - East Brunswick NJ
International Classification:
C12Q 168
G01N 33573
C07H 2104
C12N 1500
US Classification:
435 6
Abstract:
The present invention relates to methods for diagnosis of susceptibility to alcoholism or the pathological effects of alcoholism based on detection of a genetic marker in an individual. The present invention is directed generally to methods and associated compositions and kits for detecting the presence of arylsulfatase A (ASA) pseudodeficiency (PD) mutations in humans. Detection of these mutations has been surprisingly found to be a strong indicator for susceptibility to alcoholism and/or susceptibility to alcohol's pathological effects, as well as an important marker in evaluating the likelihood of metachromatic leukodystrophy (MLD).

Method Of Preparation Of Pharmaceutical Compositions

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US Patent:
55998313, Feb 4, 1997
Filed:
May 27, 1994
Appl. No.:
8/250222
Inventors:
Ronald D. Poretz - Marlboro NJ
Simon A. Chernomorsky - Morris Plains NJ
International Classification:
A01N 4338
A01N 5502
C07K 100
C07B 4700
US Classification:
514410
Abstract:
A method of preparing a pharmaceutically beneficial, pH-sensitive amphipathic drug compound is disclosed. The pH-sensitive amphipathic parent drug compound is converted to a lipophilic derivative which is then combined with a lipophilic carrier for delivery to the lysosomes of target cells. The lipophilic derivative of the parent compound is acted upon by lysosomal enzymes to yield the parent compound. The method is demonstrated for pharmaceutically beneficial porphyrins that may be used as photosensitizers in photodynamic therapy (PDT). In particular, the method is demonstrated for the esterification of chlorin e. sub. 6 and pheophorbide a for the photocytotoxic treatment of human bladder tumor cells.
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Ronald D Poretz from Lake Worth, FL, age ~85 Get Report