Ronald E Majocha

from Needham, MA

Deceased

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Ronald Majocha Phones & Addresses

Needham, MA
New Britain, CT
Sharon, MA
Marlborough, CT
Framingham, MA

Publications

Us Patents

Reversal Of .Beta./A4 Amyloid Peptide Induced Morphological Changes In Neuronal Cells By Antisense Oligonucleotides

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US Patent:

56706340, Sep 23, 1997

Filed:

Jun 1, 1995

Appl. No.:

8/456420

Inventors:

Charles A. Marotta - Cambridge MA
Ronald E. Majocha - Needham MA
Sudhir Agrawal - Shrewsbury MA

Assignee:

The General Hospital Corporation - Boston MA

International Classification:

C07H 2100
C12N 1511

US Classification:

536 231

Abstract:

The invention provides oligonucleotides that inhibit the expression of. beta. /A4 peptide of Alzheimer's disease and Down's syndrome, and further provides methods for reversing morphological changes caused in neuronal cells by. beta. /A4 peptide.

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