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Richard W Vachet

from Belchertown, MA
Age ~52

Richard Vachet Phones & Addresses

  • 1 Segur Ln, Belchertown, MA 01007 (413) 323-8462
  • 143 Buffam Rd, Amherst, MA 01002 (413) 256-1648
  • Pelham, MA
  • Alexandria, VA
  • Chapel Hill, NC
  • Richmond, VA
  • 1 Segur Ln, Belchertown, MA 01007

Work

Position: Healthcare Support Occupations

Education

Degree: Associate degree or higher

Publications

Us Patents

Multiplexed Tandem Mass Spectrometry

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US Patent:
7772549, Aug 10, 2010
Filed:
Nov 28, 2006
Appl. No.:
11/604965
Inventors:
Richard W. Vachet - Belchertown MA, US
Jonathan Wilson - Shirley MA, US
Assignee:
University of Massachusetts - Boston MA
International Classification:
B01D 59/44
H01J 49/40
US Classification:
250290, 250286
Abstract:
One or more methods for determination and/or deconvolution of complex mass spectra, using quadrupole ion trap mass spectrometry.

Multiplexed Tandem Mass Spectrometry

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US Patent:
20050263693, Dec 1, 2005
Filed:
May 24, 2005
Appl. No.:
11/136127
Inventors:
Richard Vachet - Belchertown MA, US
Jonathan Wilson - Northampton MA, US
International Classification:
H01J049/00
US Classification:
250282000
Abstract:
One or more methods for multiplexed determination and deconvolution of complex mass spectra, using quadrupole ion trap mass spectrometry

Polymeric Reverse Micelles As Selective Extraction Agents And Related Methods Of Maldi-Ms Analysis

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US Patent:
20120183983, Jul 19, 2012
Filed:
Aug 11, 2008
Appl. No.:
12/672976
Inventors:
Sankaran Thayumanavan - Amherst MA, US
Richard Vachet - Belchertown MA, US
Elamprakash N. Savariar - San Diego CA, US
Marianny Y. Combariza - Predecuesta, CO
International Classification:
G01N 27/62
G01N 1/18
US Classification:
435 23, 436178, 436 86
Abstract:
Methods for liquid-liquid extraction, as can be effected using polymeric reverse micelles, such methods as can be used in conjunction with various mass spectrometric techniques.

Compositions And Methods For Protein Labeling, Modification, Analysis, And Targeted Delivery

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US Patent:
20210380635, Dec 9, 2021
Filed:
Jun 28, 2019
Appl. No.:
17/254433
Inventors:
- Boston MA, US
Richard W. Vachet - Belchertown MA, US
Jiaming Zhuang - Amherst MA, US
Bo Zhao - Sunderland MA, US
International Classification:
C07K 1/13
C07C 229/30
A61K 47/68
C07D 213/20
C07D 213/74
C07C 69/593
C07C 271/28
C07C 235/28
C07C 229/34
C07C 323/54
C07C 311/53
A61K 47/54
Abstract:
The invention relates to chemically reactive and/or biologically active compounds, reagents and compositions thereof. More particularly, the invention provides novel reagents that are useful in chemical synthesis, functionalization, delivery, probing and/or analytical measurements of small molecule drugs, proteins, antibodies and other biomolecules. The invention provides novel biologically active agents useful as diagnostics or therapeutics, and related composition and methods of uses thereof.

Method For The Comparison Of Protein Higher Order Structures

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US Patent:
20170122963, May 4, 2017
Filed:
May 21, 2015
Appl. No.:
15/312434
Inventors:
Eric M. GRABAN - Bloomington IN, US
Richard VACHET - Belchertown MA, US
- Bloomington IN, US
- Boston MA, US
International Classification:
G01N 33/68
Abstract:
Some aspects of the disclosure include methods for comparing the higher order structures (HOS) of proteins using covalent labeling agents which allow for the direct comparison of changes in the HOS of protein therapeutics using mass spectrometry. The inventive methods can be used to access the effect of changing the process of producing and/or storing complex biologic compounds as well as determining if the HOS of a protein therapeutic has spontaneously changed during storage. Still other uses include comparing branded biologic therapeutic compounds to biosimilar compounds, and measuring changes in the aggregation states of proteins.
Richard W Vachet from Belchertown, MA, age ~52 Get Report