US Patent:
20060263864, Nov 23, 2006
Inventors:
Robert Busby - Weymouth MA, US
Brian Cali - Arlington MA, US
Peter Hecht - Newton MA, US
Douglas Holtzman - Jamaica Plain MA, US
Kevin Madden - Arlington MA, US
Mary Maxon - San Francisco CA, US
G. Milne - Brookline MA, US
Thea Norman - Belmont MA, US
John Royer - Lexington MA, US
Jeff Silva - Beverly MA, US
Eric Summers - Brookline MA, US
Lixin Zhang - Lexington MA, US
Maria Mayorga - Somerville MA, US
Toby Feibelman - Lincoln MA, US
Reed Doten - Framingham MA, US
International Classification:
C12P 17/06
C12P 7/62
C12N 15/74
C12N 1/16
US Classification:
435125000, 435135000, 435484000, 435254300
Abstract:
Methods for improving secondary metabolite production by modulating certain genes involved in secondary metabolite production, including genes encoding CreA, AreA, GanB, Gna3, FadA, Gna1, Gpa1, RfeH, An09, PacC, Lys14, LovU, Ste7, Pde2, Nc1, Vps34 and fungal homologs thereof.