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Randy Shen

from Sunnyvale, CA
Age ~59
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Related to:
Christine S Shen, 59
Connected to:
Albert Shen, 45Ann S Shen, 84Barre W Shen, 33Chiayi Shen, 75Chunfeng Shen, 51Dongmin M Shen, 66En C Shen, 43Erica T Shen, 33Eugenie Shen, 68Fan Shen, 66

Randy Shen Phones & Addresses

  • 1093 Lorne Way, Sunnyvale, CA 94087 (408) 246-6342
  • 3440 Warburton Ave, Santa Clara, CA 95051
  • San Antonio, TX
  • 838 Blake St, Indianapolis, IN 46202

Work

Address: 3200 Lakeside Dr, Santa Clara, CA 95054 Specialities: Intellectual Property - 100%

Education

School / High School: Santa Clara Univ Sol

Ranks

Licence: California - Active Date: 2008

Professional Records

Lawyers & Attorneys

Randy Shen Photo 1

Randy Shen, Santa Clara CA - Lawyer

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Address:
3200 Lakeside Dr, Santa Clara, CA 95054
Licenses:
California - Active 2008
Education:
Santa Clara Univ Sol
Univ Of Western Ontario
Specialties:
Intellectual Property - 100%

Publications

Us Patents

Maintaining A Fixed Distance By Providing An Air Cushion During Coating Of A Medical Device

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US Patent:
8647702, Feb 11, 2014
Filed:
Jun 10, 2011
Appl. No.:
13/158101
Inventors:
Randy Shen - Sunnyvale CA, US
Michael J. Leonard - Palo Alto CA, US
Anthony S. Andreacchi - San Jose CA, US
Assignee:
Abbott Laboratories - Santa Clara CA
International Classification:
A61M 25/00
US Classification:
427 228, 427 21, 118305, 118320
Abstract:
System and method for coating an expandable member of a medical device comprising a support structure to support the expandable member and an applicator positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A positioning device maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by ejecting a pressurized medium against the surface of the expandable member.

Influenza Combinatorial Antigen Vaccine

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US Patent:
20090169576, Jul 2, 2009
Filed:
Oct 26, 2006
Appl. No.:
12/091423
Inventors:
Roberto Crea - San Mateo CA, US
Mario H. Genero - Buenos Aires, AR
Guido Cappuccilli - San Mateo CA, US
Randy Shen - Sunnyvale CA, US
International Classification:
A61K 39/145
A61P 31/16
A61P 37/04
US Classification:
4241861
Abstract:
The invention provides a combinatorial influenza vaccine composition for use in providing prophylactic protection in humans against influenza viruses or animals, and a method of producing the vaccine.

Universal Fibronectin Type Iii Binding-Domain Libraries

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US Patent:
20090176654, Jul 9, 2009
Filed:
Aug 11, 2008
Appl. No.:
12/228404
Inventors:
Guido Cappuccilli - San Mateo CA, US
Roberto Crea - San Mateo CA, US
Randy Shen - Sunnyvale CA, US
Craig A. Hokanson - Pleasanton CA, US
Peter B. Kirk - San Mateo CA, US
David R. Liston - San Mateo CA, US
Assignee:
ProtElix, Inc. - Hayward CA
International Classification:
C40B 30/04
C40B 50/06
C40B 40/10
C40B 40/08
C40B 40/02
C07K 14/00
US Classification:
506 9, 506 26, 506 18, 506 17, 506 14, 530324
Abstract:
Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.

Method Of Producing Human Igg Antibodies With Enhanced Effector Functions

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US Patent:
20090215639, Aug 27, 2009
Filed:
Apr 26, 2006
Appl. No.:
11/912568
Inventors:
Roberto Crea - Foster City CA, US
Arvind Rajpal - San Francisco CA, US
Guido Cappuccilli - San Mateo CA, US
Toshihiko Takeuchi - Oakland CA, US
Ramesh Bhatt - Belmont CA, US
Randy Shen - Santa Clara CA, US
Assignee:
Bioren, Inc. - New York NY
International Classification:
C40B 30/04
C40B 30/00
C12P 19/34
US Classification:
506 9, 506 7, 435 915
Abstract:
A method for generating human IgGantibodies with enhanced Fc effector function is disclosed. In practicing the method, an IgGFc look-through mutagenesis (LTM) coding library directed at four receptor-contact regions of the Fc C2 portion of in human IgGFc is expressed in a system in which the mutated Fc fragments are displayed on the surfaces of the expression cells. The fragments are then screened for altered binding affinity to a selected Fc receptor or other Fc-binding protein. The selected mutations may be used, in turn, to guide the selection of multiple substitutions in the construction of a walk-through mutation (WTM) library, for generating additional Fc fragment mutations with desired binding properties. The antibodies so produced have a variety of therapeutic and diagnostic applications.

Antibody Ultrahumanization By Predicted Mature Cdr Blasting And Cohort Library Generation And Screening

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US Patent:
20090318297, Dec 24, 2009
Filed:
Nov 10, 2006
Appl. No.:
12/085175
Inventors:
Guido Cappucilli - San Mateo CA, US
Roberto Crea - San Mateo CA, US
Randy Shen - Sunnyvale CA, US
Rarnesh Bhatt - Belmont CA, US
Assignee:
Pfizer, Inc. - New York NY
International Classification:
C40B 10/00
C40B 40/10
C40B 30/04
C40B 40/08
US Classification:
506 1, 506 18, 506 9, 506 17
Abstract:
Methods and compositions directed to improved universal antibody libraries that rationally exploit human diversity information contained within reference antibody libraries, such as universal antibody libraries, are disclosed. The disclosed processes involve use of a query CDR sequence to guide incorporation of human antibody diversity present within the reference library into cohort libraries of the invention. Methods for making and screening such cohort libraries for isolating therapeutics suitable for treating disease are also disclosed.

Method For Producing Viral Vaccine And Therapeutic Peptide Antigens

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US Patent:
20100068224, Mar 18, 2010
Filed:
Apr 24, 2007
Appl. No.:
12/297162
Inventors:
Roberto CREA - San Mateo CA, US
Randy Shen - Sunnyvale CA, US
International Classification:
A61K 39/295
A61P 31/16
US Classification:
4242021
Abstract:
A method of producing viral antigens for use in a vaccine or therapeutic composition against infection by a virus, and a composition produced thereby, are disclosed. The method is applicable to viruses having a plurality of subtypes whose protein sequences for at least one viral protein or polyprotein are known. Regions of a selected viral protein that (i) are known or predicted to bind to MHC proteins in host antigen-presenting cells, and (ii) have a moderate amino acid variability within the virus subtypes are systematically varied in amino acid sequence, and tested for enhanced binding to MHC proteins. The composition includes those peptides having the highest binding affinity for MHC proteins.

Universal Fibronectin Type Iii Binding-Domain Libraries

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US Patent:
20100152063, Jun 17, 2010
Filed:
Sep 18, 2009
Appl. No.:
12/562992
Inventors:
Guido Cappuccilli - San Mateo CA, US
Roberto Crea - San Mateo CA, US
Randy Shen - Sunnyvale CA, US
Craig A. Hokanson - Pleasanton CA, US
Peter B. Kirk - San Mateo CA, US
David R. Liston - San Mateo CA, US
Assignee:
ProtElix, Inc. - Hayward CA
International Classification:
C40B 40/08
C40B 40/10
US Classification:
506 17, 506 18
Abstract:
Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens.

Universal Fibronectin Type Iii Binding-Domain Libraries

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US Patent:
20110021746, Jan 27, 2011
Filed:
Jun 21, 2010
Appl. No.:
12/820018
Inventors:
Guido Cappuccilli - San Mateo CA, US
Roberto Crea - San Mateo CA, US
Randy Shen - Sunnyvale CA, US
Craig A. Hokanson - Pleasanton CA, US
Peter B. Kirk - San Mateo CA, US
David R. Liston - San Mateo CA, US
International Classification:
C07K 14/00
US Classification:
530324
Abstract:
Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having hign binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins.
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Randy Shen from Sunnyvale, CA, age ~59 Get Report