US Patent:
20090304746, Dec 10, 2009
Inventors:
Alessandro Sette - La Jolla CA, US
John Sidney - San Diego CA, US
Scott Southwood - Santee CA, US
Brian D. Livingston - San Diego CA, US
Robert Chesnut - Cardiff-by-the-Sea CA, US
Denise Marie Baker - San Diego CA, US
Esteban Celis - Rochester MN, US
Ralph T. Kubo - Carlsbad CA, US
Howard M. Grey - La Jolla CA, US
International Classification:
A61K 39/29
C07K 7/06
C07K 7/08
A61K 38/08
A61K 38/10
A61K 31/7052
C07K 14/00
G01N 33/53
A61K 38/16
A61P 31/12
US Classification:
4242281, 530328, 530327, 514 16, 514 15, 514 14, 514 44 R, 530329, 530326, 530325, 530324, 435 724, 514 13, 514 12
Abstract:
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare HCV epitopes, and to develop epitope-based vaccines directed towards HCV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HCV infection.