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Ralph T Kubo

from Carlsbad, CA
Age ~82

Ralph Kubo Phones & Addresses

  • 6921 Pear Tree Dr, Carlsbad, CA 92008 (760) 431-8684
  • 12635 Futura St, San Diego, CA 92130 (858) 792-1063
  • Denver, CO

Publications

Us Patents

Inducing Cellular Immune Responses To Hepatitis B Virus Using Peptide And Nucleic Acid Compositions

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US Patent:
6689363, Feb 10, 2004
Filed:
Jan 27, 1999
Appl. No.:
09/239043
Inventors:
Alessandro Sette - La Jolla CA
John Sidney - La Jolla CA
Scott Southwood - Santee CA
Maria A. Vitiello - La Jolla CA
Brian D. Livingston - San Diego CA
Esteban Celis - Rochester MN
Ralph T. Kubo - Carlsbad CA
Howard M. Grey - La Jolla CA
Robert W. Chesnut - Cardiff-by-the-Sea CA
Assignee:
Epimmune Inc. - San Diego CA
International Classification:
A61K 3800
US Classification:
4241891, 4241851, 4241861, 530324, 530327, 530328
Abstract:
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to develop epitope-based vaccines directed towards HBV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HBV infection.

Inducing Cellular Immune Responses To Hepatitis B Virus Using Peptide Compositions

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US Patent:
7611713, Nov 3, 2009
Filed:
Sep 4, 2003
Appl. No.:
10/654601
Inventors:
Alessandro Sette - La Jolla CA, US
John Sidney - San Diego CA, US
Scott Southwood - Santee CA, US
Maria Vitiello - La Jolla CA, US
Brian Livingston - San Diego CA, US
Esteban Celis - Rochester MN, US
Ralph Kubo - Carlsbad CA, US
Howard Grey - La Jolla CA, US
Robert Chesnut - Cardiff-by-the-Sea CA, US
Assignee:
Pharmexa Inc. - San Diego CA
International Classification:
A61K 38/00
A61K 39/00
A61K 39/12
A61K 39/29
US Classification:
4241891, 4241841, 4241921, 4242281, 530300, 530328
Abstract:
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to develop epitope-based vaccines directed towards HBV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HBV infection.

Hla Binding Peptides And Their Uses

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US Patent:
20020168374, Nov 14, 2002
Filed:
Mar 20, 1997
Appl. No.:
08/821739
Inventors:
RALPH T. KUBO - CARLSBAD CA, US
HOWARD M. GREY - LA JOLLA CA, US
ALESSANDRO SETTE - LA JOLLA CA, US
ESTEBAN CELIS - ROCHESTER MN, US
International Classification:
A61K039/38
C07K007/00
C07K017/00
C07K016/00
A61K038/04
C12N005/08
A61K039/00
C07K005/00
US Classification:
424/185100, 435/372300, 530/328000
Abstract:
The present invention provides peptide compositions capable of specifically binding selected MHC alleles and inducing T cell activation in T cells restricted by the MHC allele. The peptides are useful to elicit an immune response against a desired antigen.

Inducing Cellular Immune Responses To Human Immunodeficiency Virus-1 Using Peptide And Nucleic Acid Compositions

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US Patent:
20050271676, Dec 8, 2005
Filed:
Jan 28, 2005
Appl. No.:
11/045024
Inventors:
Alessandro Sette - La Jolla CA, US
John Sidney - San Diego CA, US
Scott Southwood - Santee CA, US
Brian Livingston - San Diego CA, US
Robert Chesnut - Cardiff-by-the-Sea CA, US
Denise Baker - San Diego CA, US
Esteban Celis - Rochester MN, US
Ralph Kubo - Carlsbad CA, US
Howard Grey - La Jolla CA, US
International Classification:
C07H021/04
A61K039/00
US Classification:
424185100, 435069300, 435320100, 435325000, 536023500, 530326000, 530327000
Abstract:
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare human immunodeficiency virus (HIV) epitopes, and to develop epitope-based vaccines directed towards HIV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HIV infection.

Hla Binding Motifs And Peptides And Their Uses

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US Patent:
20070055049, Mar 8, 2007
Filed:
Apr 6, 2004
Appl. No.:
10/817970
Inventors:
Howard Grey - La Jolla CA, US
Alessandro Sette - La Jolla CA, US
John Sidney - La Jolla CA, US
Scott Southwood - Santee CA, US
Ralph Kubo - Carlsbad CA, US
Esteban Celis - Rochester MN, US
Robert Chesnut - Cardiff-by-the-Sea CA, US
W. Kast - La Canada CA, US
International Classification:
C07K 14/74
US Classification:
530350000
Abstract:
The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoproteins encoded by HLA alleles and inducing T cell activation in T cells restricted by the allele. The peptides are useful to elicit an immune response against a desired antigen.

Inducing Cellular Immune Responses To Hepatitis B Virus Using Peptide And Nucleic Acid Compositions

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US Patent:
20070059799, Mar 15, 2007
Filed:
Sep 18, 2006
Appl. No.:
11/522314
Inventors:
Alessandro Sette - La Jolla CA, US
John Sidney - La Jolla CA, US
Scott Southwood - Santee CA, US
Maria Vitiello - La Jolla CA, US
Brian Livingston - San Diego CA, US
Esteban Celis - Tampa FL, US
Ralph Kubo - Carlsbad CA, US
Howard Grey - La Jolla CA, US
Robert Chesnut - Cardiff-by-the-sea CA, US
Assignee:
Pharmexa Inc. - San Diego CA
International Classification:
C12Q 1/68
C12P 21/06
US Classification:
435069100, 435006000
Abstract:
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to develop epitope-based vaccines directed towards HBV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HBV infection.

Hla Binding Motifs And Peptides And Their Uses

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US Patent:
20080260762, Oct 23, 2008
Filed:
Oct 30, 2007
Appl. No.:
11/978519
Inventors:
Howard M. Grey - La Jolla CA, US
Alessandro Sette - La Jolla CA, US
John Sidney - San Diego CA, US
Scott Southwood - Santee CA, US
Ralph T. Kubo - Carlsbad CA, US
Esteban Celis - Rochester MN, US
Robert Chesnut - Cardiff-by-the-Sea CA, US
W. Martin Kast - La Canada CA, US
International Classification:
A61K 39/00
C07K 7/06
C07K 14/00
US Classification:
4241851, 530327, 530328, 530329, 530326, 530324
Abstract:
The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoproteins encoded by HLA alleles and inducing T cell activation in T cells restricted by the allele. The peptides are useful to elicit an immune response against a desired antigen.

Inducing Cellar Immune Responses To Hepatitis C Virus Using Peptide And Nucleic Acid Compositions

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US Patent:
20090304746, Dec 10, 2009
Filed:
Oct 31, 2007
Appl. No.:
11/980348
Inventors:
Alessandro Sette - La Jolla CA, US
John Sidney - San Diego CA, US
Scott Southwood - Santee CA, US
Brian D. Livingston - San Diego CA, US
Robert Chesnut - Cardiff-by-the-Sea CA, US
Denise Marie Baker - San Diego CA, US
Esteban Celis - Rochester MN, US
Ralph T. Kubo - Carlsbad CA, US
Howard M. Grey - La Jolla CA, US
International Classification:
A61K 39/29
C07K 7/06
C07K 7/08
A61K 38/08
A61K 38/10
A61K 31/7052
C07K 14/00
G01N 33/53
A61K 38/16
A61P 31/12
US Classification:
4242281, 530328, 530327, 514 16, 514 15, 514 14, 514 44 R, 530329, 530326, 530325, 530324, 435 724, 514 13, 514 12
Abstract:
This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare HCV epitopes, and to develop epitope-based vaccines directed towards HCV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HCV infection.
Ralph T Kubo from Carlsbad, CA, age ~82 Get Report