US Patent:
20120130129, May 24, 2012
Inventors:
Kevin G. Pinney - Woodway TX, US
Madhavi Sriram - Winston-Salem NC, US
Clinton George - Hewitt TX, US
Rajendra P. Tanpure - Waco TX, US
Assignee:
BAYLOR UNIVERSITY - Waco TX
International Classification:
C07C 213/00
C07C 45/00
C07C 41/01
C07C 201/12
US Classification:
564428, 568306, 568314, 568586
Abstract:
The disclosed process can efficiently synthesize functionalized benzosuberenes. The process provides an improved method of production of benzosuberene and compounds containing a benzosuberene moiety, which is characterized by a ring closing methodology comprising reaction of a 5-phenylpentanoic acid with Eaton's reagent to form the benzosuberone. The process, optionally, further includes steps for adding a functional group at the ketone position.
