US Patent:
20100299289, Nov 25, 2010
Inventors:
Rahul SIMHA - Springfield VA, US
Guanyu Wang - Fairfax VA, US
Chen Zeng - Rockville MD, US
Assignee:
The George Washington University - Washington DC
International Classification:
G06F 15/18
G06F 17/11
Abstract:
A system and method of obtaining information concerning the structure-function relationship of biological networks can be studied holistically through the ensemble characterization of all the networks that realize a given biological function. A logic-based approach enables significant advances in computability and concept development (minimality and reducibility). The approach is applied to a biologically relevant trajectory and reveals some interesting properties. By using the approach, a cell cycle network is decomposed into three components with the functioning of each component explained.