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Rafael A Fissore

from Amherst, MA
Age ~64
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Also known as:
Rafael Antonio Fissore, Raphael A Fissore, Rafael F
Phone and address:
50 Farview Way, Amherst, MA 01002
Related to:
Julia Fissore
Connected to:
Jennifer Fiste, 52Cindy A Fistel, 67April M Fister, 51Jack L Fister, 84Jay K Fister, 72Jeremy E Fister, 48Jonathon D Fister, 47Megan V Fister, 46Scott C Fister, 55Steven R Fister, 63

Rafael Fissore Phones & Addresses

  • 50 Farview Way, Amherst, MA 01002
  • 562 Montague Rd, Amherst, MA 01002
  • Woodstock, VT
  • Brattleboro, VT
  • Townshend, VT
  • Sunderland, MA
  • Boston, MA

Publications

Us Patents

Sperm Factor Oscillogenin

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US Patent:
20070174926, Jul 26, 2007
Filed:
Feb 14, 2003
Appl. No.:
10/344723
Inventors:
Rafael Fissore - Amherst MA, US
International Classification:
A01K 67/027
G01N 33/567
G01N 33/53
C12N 9/00
US Classification:
800021000, 435325000, 435183000, 435007200
Abstract:
The specification described a novel compound, oscillogenin, which is an active agent in furthering oocyte fertilization by sperm or in parthenogenetic activation of an oocyte. The specification discloses methods of isolating oscillogenin to modulate fertility and to enhance parthenogenetic activation of oocytes for nuclear transfer or in ICSI procedures, and methods of using oscillogenin to test amounts of it in sperm and thus sperm fertility

Phospholipase C Zeta Mediated Oocyte Activation, Compositions For Use Therein, And Assays For Detecting And Identifying Agents For Treating Male Infertility

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US Patent:
20080175827, Jul 24, 2008
Filed:
Nov 19, 2007
Appl. No.:
11/942406
Inventors:
Rafael A. Fissore - Amherst MA, US
Pablo Visconti - Amherst MA, US
Manabu Kurokawa - Durham NC, US
Sook-Young Yoon - Amherst MA, US
Daniel R. Grow - Long Meadow MA, US
Teru J. Jellerette - Shutesbury MA, US
Jose Bernardo Cibelli - East Lansing MI, US
Pablo Juan Ross - Bath MI, US
Assignee:
Michigan State University - East Lansing MI
University of Massachussetts - Boston MA
Baystate Health, Inc. - Springfield MA
International Classification:
A61K 48/00
C12N 5/00
C12N 15/00
C12Q 1/68
A01N 1/02
C12Q 1/42
US Classification:
424 9321, 435377, 435455, 435 2, 435 21, 435 6
Abstract:
The invention relates to the use of phospholipase C zeta in inducing or promoting the activation of oocytes, preferably human oocytes, nuclear transfer embryos, parthenogenic embryos, cross species embryos and during in vitro fertilization.The invention further relates to methods of detecting levels of expression of phospholipase c zeta in sperm as a means of detecting male infertility.The invention also relates to the use of phospholipase C zeta to treat male infertility. Still further the invention relates to the recombinant cells that are engineered to express phospholipase C zeta, preferably under inducible conditions.Also, the invention relates to antibodies specific to phospholipase C zeta, preferably human phospholipase C zeta.

Sperm-Induced Cellular Activation

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US Patent:
20050025750, Feb 3, 2005
Filed:
Dec 29, 2003
Appl. No.:
10/747772
Inventors:
Rafael Fissore - Amherst MA, US
Jason Knott - Leicester MA, US
Manabu Kurokawa - Tokorozawa, JP
International Classification:
A61K048/00
C12N005/08
US Classification:
424093210, 435366000
Abstract:
The present invention provides a method for parthenogenetic activation by injection and subsequent removal of a sperm into a mammalian cell, for example, an oocyte, an embryo, a blastomere, an inner cell mass cell, or a morulae cell.
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Rafael A Fissore from Amherst, MA, age ~64 Get Report