Peter Allen Nemoto

5602159, Feb 11, 1997

Jun 6, 1995

8/470715

Edward J. Glamkowski - Warren NJ
Yulin Chiang - Covent Station NJ
Joseph T. Strupczewski - Flemington NJ
Kenneth J. Bordeau - Kintnersville PA
Peter A. Nemoto - Raritan NJ
John J. Tegeler - Bridgewater NJ

Hoechst-Roussel Pharmaceuticals, Inc. - Somerville NJ

A61K 31495
A61K 3155
A61K 31505
A61K 3144
C07D40104
C07D40300
C07D41700
C07D41900
C07D22104
C07D27504
C07D23902

514373

Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.

5633265, May 27, 1997

Jun 6, 1995

8/468993

Joseph T. Strupczewski - Flemington NJ
Grover C. Helsley - Stockton NJ
Edward J. Glamkowski - Warren NJ
Yulin Chiang - Covent Station NJ
Kenneth J. Bordeau - Kintnersville PA
Peter A. Nemoto - Raritan NJ
John J. Tegeler - Bridgewater NJ

Hoechst Marion Roussel, Inc. - Kansas City MO

A61K 31495
A61K 3155
A61K 31505
A61K 3144
C07D40104
C07D40304
C07D41704
C07D41904
C07D22104
C07D27504
C07D23902

514316

Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.

RE37729, Jun 4, 2002

Feb 3, 1999

09/240842

Edward J. Glamkowski - Warren NJ
Yulin Chiang - Convent Station NJ
Joseph T. Strupczewski - Flemington NJ
Kenneth J. Bordeau - Kintnersville PA
Peter A. Nemoto - Evanston IL
John J. Tegeler - Bridgewater NJ

Aventis Pharmaceuticals Inc. - Bridgewater NJ

A61K 31495

514321, 514 63, 514217, 5142338, 514249, 51425301, 51425404, 51425406, 514258, 514300, 514301, 514307, 514309, 514311, 514312, 514314, 514316, 514322, 514373, 514379, 514403, 514411, 540576, 540588, 544121, 544129, 544229, 544279, 544295, 544310, 544316, 544317, 544318, 544333, 544353, 544361, 544362, 544364, 544366, 544368, 546 14, 546 98, 546 99, 546100, 546113, 546122, 546135, 546141, 546142, 546143, 546144, 546146, 546148, 546149, 546153, 546155, 546156, 546157, 546158, 546183, 546193, 546199, 546198

Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.

6420390, Jul 16, 2002

Apr 19, 2000

09/556116

Joseph T. Strupczewski - Flemington NJ
Edward J. Glamkowski - Warren NJ
Yulin Chiang - Covent Station NJ
Kenneth J. Bordeau - Kintnersville PA
Peter A. Nemoto - Raritan NJ
John J. Tegeler - Bridgewater NJ

Aventis Pharmaceuticals Inc. - Bridgewater NJ

A61K 31445

514321, 514322, 546198, 546199

Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.

6878706, Apr 12, 2005

Mar 27, 2003

10/400385

Thomas A. Gilmore - Salem MA, US
Eugene Richard Hickey - Danbury CT, US
Weimin Liu - Sandy Hook CT, US
Peter Allen Nemoto - Southbury CT, US
Denice M. Spero - West Redding CT, US

Boehringer Ingelheim Pharmaceuticals Inc. - Ridgefield CT

A61K031/535
A61K031/4965
A61K031/44
A01N043/70
A01N043/12

5142375, 5142392, 51425501, 51425506, 514306, 514309, 514330, 514331, 514419, 514448, 514463, 514469, 514609, 544146, 544153, 544163, 544355, 544391, 544392, 544406, 546141, 546146, 546226, 548492, 549 57, 549471, 549441, 564103, 564105, 564106

Compounds according to the following formula (I): wherein the variables Q and Rto Rare as described herein, which reversibly inhibit the cysteine proteases, such as cathepsins K, S, F, L and B; pharmaceutical compositions containing such compounds, and method of treating diseases and pathological conditions exacerbated by these cysteine proteases such as, but not limited to rheumatoid arthritis, multiple sclerosis and other autoimmune diseases, osteoporosis, asthma, Alzheimer's disease, atherosclerosis and endometriosis.

6946446, Sep 20, 2005

Feb 23, 2001

09/791408

Zhenkun Ma - Gurnee IL, US
Peter Nemoto - Danbury CT, US
Suoming Zhang - Gainesville FL, US
Hong Yong - Grayslake IL, US
Yat Sun Or - Cambridge MA, US

Abbott Laboratories - Abbott Park IL

A01N043/04

514 29, 536 73, 536 74

The invention relates to novel methods for using macrolide anti-infective agents. The macrolide anti-infective agents demonstrate antibacterial activity against multi-drug resistant strains of bacteria and, in particular, methicillin-resistant (MRSA). Methods for inhibiting the activity of multi-drug resistant bacterial organisms and methods for treating a bacterial infection caused by such organisms are described herein.

6964956, Nov 15, 2005

Jun 3, 2003

10/453175

Charles L. Cywin - Bethel CT, US
Zhidong Chen - New Milford CT, US
Roman Wolfgang Fleck - Greenwich CT, US
Ming-Hong Hao - Ridgefield CT, US
Eugene Hickey - Danbury CT, US
Weimin Liu - Sandy Hook CT, US
Daniel Richard Marshall - Norwalk CT, US
Peter Nemoto - Southbury CT, US
Ronald John Sorcek - Bethel CT, US
Sanxing Sun - Danbury CT, US
Jiang-Ping Wu - Danbury CT, US
Tina Morwick - New Milford CT, US
Jonathan Emeigh - Gilbertsville PA, US

Boehringer Ingelheim Pharmaceuticals, Inc. - Ridgefield CT

A61K031/4365
A61K031/551
A61K031/496
C07D495/04

51421115, 51421704, 514218, 5142282, 51425304, 514301, 540492, 540544, 540575, 540597, 544 60, 544362, 546114

Disclosed are compounds of formula (I): wherein Rand Rare defined herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.

6974870, Dec 13, 2005

Dec 6, 2003

10/730172

Charles L. Cywin - Bethel CT, US
Can Mao - New Milford CT, US
Jonathan Emeigh - Danbury CT, US
Roman Wolfgang Fleck - Greenwich CT, US
Ming-Hong Hao - Ridgefield CT, US
Eugene Hickey - Danbury CT, US
Weimin Liu - Sandy Hook CT, US
Daniel Richard Marshall - Norwalk CT, US
Tina Morwick - New Milford CT, US
Peter Nemoto - Southbury CT, US
Ronald John Sorcek - Bethel CT, US
Sanxing Sun - Danbury CT, US
Jiang-Ping Wu - Danbury CT, US
Erick Young - Danbury CT, US
Darren DiSalvo - New Milford CT, US
John Ginn - New Milford CT, US
Pier Cirillo - Woodbury CT, US

Boehringer Ingelheim Phamaceuticals, Inc. - Ridgefield CT

C07D495/04
A61K031/4365
A61K031/497
A61K031/5377

546114, 514218, 51421115, 51421704, 5142338, 51425304, 51425505, 514256, 5142282, 514301, 540492, 540544, 540575, 540597, 544 582, 544 60, 544127, 544 33, 544362, 544405

Disclosed are compounds of formula (I): wherein Rand Rare defined herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.