US Patent:
20140072517, Mar 13, 2014
Inventors:
Janet Morrow - Williamsville NY, US
Pavel Tsitovich - Amherst NY, US
Assignee:
The Research Foundation of State University of New - Amherst NY
International Classification:
A61K 49/10
C07D 213/68
C07D 471/04
C07D 213/53
US Classification:
424 9361, 546332, 546291, 546 88, 546257, 546 2, 546 10
Abstract:
Compounds and uses of the compounds are provided. The compounds can be used as Fe(II) sequestering compounds. For example, these compounds can be used to sequester Fe(II) in cells, organs, vasculature, or tissues. Also, provided are compositions and methods of using the them for sequestering Fe(II) in an individual. The compounds can be used as MRI paraCEST contrast agents.