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Pamela J Hornby

from New Orleans, LA
Age ~68

Pamela Hornby Phones & Addresses

  • 2724 Calhoun St, New Orleans, LA 70118 (504) 866-0491
  • 713 Buckley Rd, Lower Gwynedd, PA 19002 (215) 654-9077
  • Ambler, PA
  • 713 Buckley Rd, Blue Bell, PA 19422 (215) 654-9077
  • Washington, DC

Work

Company: Biotechnology - Radnor, PA 2012 Position: Senior scientific director and research fellow biologics research

Education

School / High School: School of Biological Sciences 1984 Specialities: Ph.D.

Resumes

Resumes

Pamela Hornby Photo 1

Pamela Hornby Radnor, PA

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Work:
Biotechnology
Radnor, PA
2012 to Jul 2012
Senior Scientific Director and Research Fellow Biologics Research

Biotechnology Center of Excellence

2008 to 2012
Senior Research Fellow Biologics Research

Immunobiology, Centocor R&D
Radnor, PA
2006 to 2008
Senior Research Fellow

Johnson & Johnson
Spring House, PA
2002 to 2006
Senior Research Fellow and Enterology Biology Team Leader

Neuroscience Center of Excellence

1999 to 2002
Professor of Pharmacology (tenured)

Louisiana State University Health Sciences
New Orleans, LA
1990 to 1994
Assistant Professor

Medical School
Washington, DC
1988 to 1990
Assistant Professor of Pharmacology

Education:
School of Biological Sciences
1984
Ph.D.

Queens University
Belfast, IE
1979
B.Sc. in Zoology

University of Kentucky

Publications

Us Patents

Methods Of Treating Inflammation Using Prokineticin 1 Receptor Antagonists

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US Patent:
8188081, May 29, 2012
Filed:
Jun 9, 2010
Appl. No.:
12/797266
Inventors:
John R. Mabus - East Greenville PA, US
Jeffrey M. Palmer - Chalfont PA, US
Stephen M. Prouty - Doylestown PA, US
Pamela J. Hornby - Penllyn PA, US
Paul R. Wade - Philadelphia PA, US
Assignee:
Janssen Pharmaceutica, NV
International Classification:
A61K 31/53
A01N 43/64
US Classification:
514241, 514245
Abstract:
The present invention relates to prokineticin 1 receptor antagonists and methods of using the same to modulate intestine epithelial functions and to treat inflammation in the intestine in a mammal.

Prokineticin 1 Receptor

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US Patent:
20070021422, Jan 25, 2007
Filed:
Jun 27, 2006
Appl. No.:
11/374683
Inventors:
John Mabus - East Greenville PA, US
Jeffrey Palmer - Chalfont PA, US
Stephen Prouty - Doylestown PA, US
Pamela Hornby - Penllyn PA, US
Paul Wade - Philadelphia PA, US
International Classification:
A61K 31/53
A61K 31/513
US Classification:
514241000, 514269000
Abstract:
The present invention relates to methods of monitoring the biological activity of the PK1 receptor.

Stimulation Of Satiety Hormone Release

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US Patent:
20100056948, Mar 4, 2010
Filed:
Aug 25, 2009
Appl. No.:
12/546721
Inventors:
Pamela J. Hornby - Radnor PA, US
Tatiana Ort - Radnor PA, US
Radhika Kajekar - Radnor PA, US
Paul R. Wade - Philadelphia PA, US
International Classification:
A61N 1/36
G01N 33/53
A61B 5/05
US Classification:
600554, 435 71, 604 20, 607 3
Abstract:
The present invention provides, among other things, a site specific way to enhance a natural hormonal response to nutrients entering the small intestine after gastric emptying, thereby providing therapeutic value for obesity or diabetic patients. In one aspect, the present invention provides methods of stimulating the release of satiety hormone in a subject comprising applying a first electrical stimulus to a tissue in the lumen of the gastrointestinal system of the subject contemporaneously with the contacting of L-cells of the tissue with a nutrient stimulus. In another aspect, the present invention provides methods for predicting patient response to a weight loss surgery comprising applying a first electrical stimulus to a tissue of the gastrointestinal system of said patient contemporaneously with the contacting of L-cells of the tissue with a nutrient stimulus, assessing the effect of the electrical stimulus in said patient, and, correlating said effect to said patient's response to a weight loss surgery.

Prokineticin 1 Receptor

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US Patent:
20120245077, Sep 27, 2012
Filed:
Mar 26, 2012
Appl. No.:
13/429773
Inventors:
John R. Mabus - East Greenville PA, US
Jeffrey M. Palmer - Chalfont PA, US
Stephen M. Prouty - Doylestown PA, US
Pamela J. Hornby - Penllyn PA, US
Paul R. Wade - Philadelphia PA, US
International Classification:
A61K 38/00
A61P 1/00
US Classification:
514 11
Abstract:
The present invention relates to methods of monitoring the biological activity of the PK1 receptor.

Stimulation Of Satiety Hormone Release

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US Patent:
20130035559, Feb 7, 2013
Filed:
May 4, 2012
Appl. No.:
13/464470
Inventors:
Pamela J. Hornby - Radnor PA, US
Tatiana Ort - Radnor PA, US
Radhika Kajekar - Radnor PA, US
Paul R. Wade - Philadelphia PA, US
International Classification:
A61M 37/00
A61B 5/145
A61B 5/05
US Classification:
600301, 604500, 600554
Abstract:
The present invention provides a site specific way to enhance a natural hormonal response to nutrients entering the small intestine after gastric emptying, thereby providing therapeutic value for obesity or diabetic patients. In one aspect, the present invention provides methods of stimulating the release of satiety hormone in a subject comprising applying a first electrical stimulus to a tissue in the lumen of the gastrointestinal system of the subject contemporaneously with the contacting of L-cells of the tissue with a nutrient stimulus. The present invention also provides methods for predicting patient response to a weight loss surgery comprising applying a first electrical stimulus to a tissue of the gastrointestinal system of said patient contemporaneously with the contacting of L-cells of the tissue with a nutrient stimulus, assessing the effect of the electrical stimulus in said patient, and, correlating said effect to said patient's response to a weight loss surgery.
Pamela J Hornby from New Orleans, LA, age ~68 Get Report