Inventors:
Gary M. Fox - Newbury Park CA, US
John K. Sullivan - Newbury Park CA, US
Paige Holst - Camarillo CA, US
Steven Kiyoshi Yoshinaga - Thousand Oaks CA, US
Assignee:
AMGEN, INC. - Thousand Oaks CA
International Classification:
A61K 39/395
C07H 21/04
C12N 15/63
C12N 1/16
C12N 5/10
C12N 5/06
C12N 5/12
A61K 38/16
C12Q 1/68
C40B 40/08
A01K 67/027
A61K 9/00
A61K 31/711
G01N 33/53
C12P 21/00
C07K 2/00
C12Q 1/02
C07K 14/47
C07K 16/00
US Classification:
424422, 536 235, 4353201, 4352542, 435348, 435325, 435 691, 530300, 435 29, 530350, 5303879, 5303873, 5303872, 4241301, 435346, 435 71, 514 12, 514 44, 435 6, 800 14, 800 3, 506 17
Abstract:
The present invention provides B7-Like (B7-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing B7-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with B7-L polypeptides.