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Oliver R Thiel

from Lexington, MA
Age ~50

Oliver Thiel Phones & Addresses

  • 3 Anthony Rd, Lexington, MA 02420 (805) 987-5905
  • Thousand Oaks, CA
  • 355 Paseo Sabanero, Camarillo, CA 93012 (805) 987-5905
  • Ventura, CA
  • 838 Roble Ave, Menlo Park, CA 94025 (650) 473-9697

Work

Company: Amgen Feb 2018 Position: Director process development, drug substance technologies and engineering

Education

Degree: Master of Business Administration, Masters School / High School: Fernuniversität In Hagen 2015 Specialities: Economics, Business

Skills

Medicinal Chemistry • Chemistry • Technology Transfer • Drug Discovery • Organic Chemistry • Organic Synthesis • Gmp • Biotechnology • Drug Development • Lead Change • Quality By Design • Life Sciences • Pharmaceutical Industry • Regulatory Affairs • Chromatography • Bioconjugation • Process Chemistry • Cmc Development • Lc Ms • Catalysis • Safety • Mentoring

Languages

English • German • Spanish

Industries

Pharmaceuticals

Resumes

Resumes

Oliver Thiel Photo 1

Director Process Development, Drug Substance Technologies And Engineering

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Location:
Los Angeles, CA
Industry:
Pharmaceuticals
Work:
Amgen
Director Process Development, Drug Substance Technologies and Engineering

Amgen Feb 2017 - Feb 2018
Director, Process Development, Drug Substance Technology Business Operations and Strategy

Amgen Sep 2015 - Feb 2017
Director, Process Development, Pivotal Drug Substance Technologies

Amgen 2011 - 2015
Principal Scientist, Translational Sciences

Amgen 2005 - 2011
Senior Scientist, Research and Development
Education:
Fernuniversität In Hagen 2015
Master of Business Administration, Masters, Economics, Business
Stanford University 2001 - 2003
Fernuniversität In Hagen 1998 - 2000
Bachelors, Economics
Technical University of Munich 1993 - 1998
Master of Science, Masters, Chemistry
Skills:
Medicinal Chemistry
Chemistry
Technology Transfer
Drug Discovery
Organic Chemistry
Organic Synthesis
Gmp
Biotechnology
Drug Development
Lead Change
Quality By Design
Life Sciences
Pharmaceutical Industry
Regulatory Affairs
Chromatography
Bioconjugation
Process Chemistry
Cmc Development
Lc Ms
Catalysis
Safety
Mentoring
Languages:
English
German
Spanish

Publications

Us Patents

Methods Of Synthesizing Cinacalcet And Salts Thereof

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US Patent:
20090137837, May 28, 2009
Filed:
Jun 19, 2008
Appl. No.:
12/142450
Inventors:
Oliver Thiel - Camarillo CA, US
Charles Bernard - Moorpark CA, US
Robert Larsen - Newbury Park CA, US
Michael John Martinelli - Thousand Oaks CA, US
Masooma Tamim Raza - Woodland Hills CA, US
International Classification:
C07C 271/06
C07C 211/27
C07C 233/02
US Classification:
560115, 564378, 564182
Abstract:
Methods of preparing cinacalcet, cinacalcet derivatives, and salts thereof is disclosed herein. Also disclosed herein are polymorphs of cinacalcet, compositions of cinacalcet, and methods of treating a subject by administering cinacalcet, wherein cinacalcet is prepared by the disclosed methods.

Methods Of Synthesizing Cinacalcet And Salts Thereof

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US Patent:
20110281954, Nov 17, 2011
Filed:
May 17, 2011
Appl. No.:
13/109538
Inventors:
Oliver Thiel - Camarillo CA, US
Charles Bernard - Moorpark CA, US
Robert Larsen - Newbury Park CA, US
Michael John Martinelli - Thousand Oaks CA, US
Masooma Tamim Raza - Woodland Hills CA, US
International Classification:
A61K 31/137
C07C 231/12
A61P 3/00
C07C 209/62
C07C 211/30
C07C 209/68
C07C 231/14
US Classification:
514657, 564378, 564182, 564139, 564375
Abstract:
Methods of preparing cinacalcet, cinacalcet derivatives, and salts thereof is disclosed herein. Also disclosed herein are polymorphs of cinacalcet, compositions of cinacalcet, and methods of treating a subject by administering cinacalcet, wherein cinacalcet is prepared by the disclosed methods.

Method Of Conjugation Of Cys-Mabs

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US Patent:
20210346513, Nov 11, 2021
Filed:
Aug 3, 2018
Appl. No.:
16/636325
Inventors:
- THOUSAND OAKS CA, US
Dante ROMANINI - Sherman Oaks CA, US
James R. FALSEY - Moorpark CA, US
Bradley J. HERBERICH - Newbury Park CA, US
Oliver R. THIEL - Thousand Oaks CA, US
Assignee:
AMGEN INC. - THOUSAND OAKS CA
International Classification:
A61K 47/68
C07K 16/28
C07K 14/605
Abstract:
The present disclosure relates to a method of capping, reducing, and oxidizing cys-mAbs in order to provide homogenous material for subsequent conjugation reactions. The present method demonstrates robust ways to manufacture conjugates of cysteine-engineered antibodies that offer high yield and consistent product quality.
Oliver R Thiel from Lexington, MA, age ~50 Get Report