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Nyamekye Obeng-Adjei

from King of Prussia, PA
Age ~40

Nyamekye Obeng-Adjei Phones & Addresses

  • 194 E Valley Forge Rd, Kng Of Prussa, PA 19406
  • King of Prussia, PA
  • Gilbertsville, PA
  • Salisbury, MD
  • Laurel, MD
  • Lansdowne, PA
  • Burtonsville, MD
  • Philadelphia, PA
  • Upper Darby, PA
  • Alexandria, VA
  • Dumfries, VA

Publications

Us Patents

Nucleic Acid Molecule Encoding Hepatitis B Virus Core Protein And Vaccine Comprising The Same

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US Patent:
20140023613, Jan 23, 2014
Filed:
Feb 13, 2012
Appl. No.:
13/984771
Inventors:
David B Weiner - Merion PA, US
Jian Yan - Havertown PA, US
Nyamekye Obeng-Adjei - Lansdowne PA, US
Assignee:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA - Philadelphia PA
International Classification:
C07K 14/005
US Classification:
424 852, 536 2372, 4353201, 4242271, 530350
Abstract:
Provided herein are nucleic acid sequences that encode novel consensus amino acid sequence of HBV core protein, as well as genetic constructs/vectors and vaccines that express said protein sequences. Also provided herein are methods for generating an immune response against HBV using the nucleic acid sequences that are provided.

Nucleic Acid Molecule Encoding Hepatitis B Virus Core Protein And Surface Antigen Protein And Vaccine Comprising The Same

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US Patent:
20130209395, Aug 15, 2013
Filed:
Sep 19, 2012
Appl. No.:
13/622965
Inventors:
David B. WEINER - Merion PA, US
Jian YAN - Havertown PA, US
Nyamekye OBENG-ADJEI - Upper Darby PA, US
International Classification:
A61K 39/29
C12N 15/51
C12N 7/01
A61P 37/04
C12N 15/63
A61P 31/20
C07K 14/02
US Classification:
424 852, 4241891, 536 2372, 530350, 4353201, 4352351
Abstract:
Provided herein are nucleic acid sequences encoding hepatitis B virus (HBV) core proteins, surface antigen proteins, fragments and combinations thereof as well as genetic constructs/vectors and vaccines that express said protein sequences. These vaccines are able to induce an immune response peripherally and in the liver by recruiting both cellular and humoral agents. Also provided are methods for prophylactically and/or therapeutically immunizing individuals against HBV. The combination vaccine can also be used for particular design vaccines for particular levels of immune responses to HBV challenge.

Nucleic Acid Molecule Encoding Hepatitis B Virus Core Protein And Vaccine Comprising The Same

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US Patent:
20190151443, May 23, 2019
Filed:
Feb 5, 2019
Appl. No.:
16/267454
Inventors:
- Philadelphia PA, US
Jian Yan - Wallingford PA, US
Nyamekye Obeng-Adjei - Lansdowne PA, US
International Classification:
A61K 39/29
A61K 39/39
A61K 39/12
C07K 14/02
C12N 7/00
C07K 14/005
Abstract:
Provided herein are nucleic acid sequences that encode novel consensus amino acid sequences of HBV core protein, as well as genetic constructs/vectors and vaccines that express said protein sequences. Also provided herein are methods for generating an immune response against HBV using the nucleic acid sequences that are provided.

Human Respiratory Syncytial Virus Consensus Antigens, Nucleic Acid Constructs And Vaccines Made Therefrom, And Methods Of Using The Same

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US Patent:
20180346522, Dec 6, 2018
Filed:
Aug 6, 2018
Appl. No.:
16/055425
Inventors:
- Philadelphia PA, US
Daniel Choo - Lansdale PA, US
Kar Muthumani - Cherry Hill NJ, US
Nyamekye Obeng-Adjei - Lansdowne PA, US
Veronica Scott - Philadelphia PA, US
International Classification:
C07K 14/005
A61K 39/155
A61K 39/39
A61K 39/12
A61K 39/00
Abstract:
Nucleic acid molecules and compositions comprising one or more nucleic acid sequences that encode an RSV immunogen are disclosed. Nucleic acids are disclosed that comprise the sequences that encodes consensus RSV F protein or immuno-genic fragment thereof, sequences that encodes an RSV G(A) protein or immunogenic fragment thereof and sequences that encodes an RSV G(B) protein or immunogenic fragment thereof. Compositions comprising one, combinations of two or all three sequences are disclosed. The coding sequences optionally include operable linked coding sequence that encode a signal peptide. Nucleic acid molecules and compositions comprising the chemokine CC20 and/or a consensus RSV M2-1 protein or immunogenic fragment thereof are also disclosed. Immunomodulatory methods and methods of inducing an immune response against RSV are disclosed. Methods of preventing RSV infection and methods of treating individuals infected with RSV are disclosed.

Nucleic Acid Molecule Encoding Hepatitis B Virus Core Protein And Vaccine Comprising The Same

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US Patent:
20160317652, Nov 3, 2016
Filed:
Jul 19, 2016
Appl. No.:
15/213747
Inventors:
- Philadelphia PA, US
Jian Yan - Wallingford PA, US
Nyamekye Obeng-Adjei - Lansdowne PA, US
International Classification:
A61K 39/29
C12N 7/00
A61K 39/39
Abstract:
Provided herein are nucleic acid sequences that encode novel consensus amino acid sequences of HBV core protein, as well as genetic constructs/vectors and vaccines that express said protein sequences. Also provided herein are methods for generating an immune response against HBV using the nucleic acid sequences that are provided.

Nucleic Acid Molecule Encoding Hepatitis B Virus Core Protein And Surface Antigen Protein And Vaccine Comprising The Same

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US Patent:
20160114030, Apr 28, 2016
Filed:
Dec 22, 2015
Appl. No.:
14/978329
Inventors:
- Philadelphia PA, US
Jian Yan - Wallingford PA, US
Nyamekye Obeng-Adjei - Laurel MD, US
International Classification:
A61K 39/29
C12N 7/00
A61K 39/39
Abstract:
Provided herein are nucleic acid sequences encoding hepatitis B virus (HBV) core proteins, surface antigen proteins, fragments and combinations thereof as well as genetic constructs/vectors and vaccines that express said protein sequences. These vaccines are able to induce an immune response peripherally and in the liver by recruiting both cellular and humoral agents. Also provided are methods for prophylactically and/or therapeutically immunizing individuals against HBV. The combination vaccine can also be used for particular design vaccines for particular levels of immune responses to HBV challenge.

Human Respiratory Syncytial Virus Consensus Antigens, Nucleic Acid Constructs And Vaccines Made Therefrom, And Methods Of Using Same

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US Patent:
20150079121, Mar 19, 2015
Filed:
Apr 10, 2013
Appl. No.:
14/391921
Inventors:
- Philadelphia PA, US
Daniel Choo - Lansdale PA, US
Karuppiah Muthumani - Cherry Hill NJ, US
Nyamekye Obeng-Adjei - Lansdowne PA, US
Veronica Scott - Philadelphia PA, US
International Classification:
C07K 14/005
A61K 39/155
A61K 39/39
US Classification:
4241861, 536 2372, 514 44 R, 530350, 4353201
Abstract:
Nucleic acid molecules and compositions comprising one or more nucleic acid sequences that encode an RSV immunogen are disclosed. Nucleic acid are disclosed that comprise the sequences that encodes consensus RSV F protein or immunogenic fragment thereof, sequences that encodes an RSV G(A) protein or immunogenic fragment thereof and sequences that encodes an RSV G(B) protein or immunogenic fragment thereof. Compositions comprising one, combinations of two or all three sequences are disclosed. The coding sequences optionally include operable linked coding sequence that encode a signal peptide. Nucleic acid molecules and compositions comprising the chemokine CC20 and/or a consensus RSV M2-1 protein or immunogenic fragment thereof are also disclosed. Immunomodulatory methods and methods of inducing an immune response against RSV are disclosed. Method of preventing RSV infection and methods of treating individuals infected with RSV are disclosed.
Nyamekye Obeng-Adjei from King of Prussia, PA, age ~40 Get Report