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Noriyuki H Kawahata

from Wayland, MA
Age ~57
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Also known as:
Noriyuki A Kawahata, Nh Kawahata, Nori Kawahata
Phone and address:
10 Cameron Rd, Wayland, MA 01778
(508) 358-4187
Related to:
Brian L Ziegler, 64
Connected to:
Keith D Kawahata, 41Atsushi Kawai, 68Christopher S Kawai, 139Haruko Kawai, 70Kyle M Kawai, 50Nancy M Kawai, 43Risa Kawai, 38Shigeru Kawai, 73Tam Kawai, 55Tomoyasu Kawai, 53

Noriyuki Kawahata Phones & Addresses

  • 10 Cameron Rd, Wayland, MA 01778 (508) 358-4187
  • 79 Garnet Rd, West Roxbury, MA 02132
  • Boston, MA
  • Newton, MA
  • Somerville, MA
  • 72 Rawson Rd, Arlington, MA 02474 (781) 316-0291
  • 72 Rawson Rd APT 2, Arlington, MA 02474 (781) 316-0291
  • Schenectady, NY
  • La Jolla, CA
  • 72 Rawson Rd APT 2, Arlington, MA 02474 (781) 956-4680

Work

Company: Aileron therapeutics Aug 2010 to Jun 2013 Address: Cambridge, MA Position: Director, chemical development

Education

Degree: PhD School / High School: University of California, San Diego 1998 Specialities: Chemistry

Skills

Drug Discovery • Medicinal Chemistry • Organic Chemistry • High Throughput Screening • Biotechnology • Hplc • Chemistry • Purification • Peptides • Pharmaceutical Industry • Protein Chemistry • In Vitro • Mass Spectrometry • Drug Development • Peptide Synthesis • Lc Ms • Computational Chemistry • Drug Design • Organic Synthesis • Oncology • Laboratory • Molecular Modeling • Lead Change • Immunology • Cro • Gmp • Cheminformatics • Lifesciences • Nmr • Technology Transfer • In Vivo • Assay Development • Biopharmaceuticals • Small Molecules • Biomarkers • Adme • Biophysics • Lims

Industries

Pharmaceuticals

Resumes

Resumes

Noriyuki Kawahata Photo 1

Associate Director, Program

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Location:
Cambridge, MA
Industry:
Pharmaceuticals
Work:
Aileron Therapeutics - Cambridge, MA Aug 2010 - Jun 2013
Director, Chemical Development
Aileron Therapeutics - Cambridge, MA Dec 2007 - Aug 2010
Senior Principal Scientist
Schering-Plough - Cambridge, MA Feb 2005 - Nov 2007
Section Leader
NeoGenesis - Cambridge, MA Dec 1999 - Feb 2005
'Senior Scientist' to 'Principal Scientist'
ARIAD Pharmaceuticals, Inc. Jan 1998 - Dec 1999
Senior Scientist
Education:
University of California, San Diego 1998
PhD, Chemistry State University of New York College at Buffalo 1992
MS, Medicinal Chemistry Rensselaer Polytechnic Institute 1989
BS, Chemistry
Skills:
Drug Discovery
Medicinal Chemistry
Organic Chemistry
High Throughput Screening
Biotechnology
Hplc
Chemistry
Purification
Peptides
Pharmaceutical Industry
Protein Chemistry
In Vitro
Mass Spectrometry
Drug Development
Peptide Synthesis
Lc Ms
Computational Chemistry
Drug Design
Organic Synthesis
Oncology
Laboratory
Molecular Modeling
Lead Change
Immunology
Cro
Gmp
Cheminformatics
Lifesciences
Nmr
Technology Transfer
In Vivo
Assay Development
Biopharmaceuticals
Small Molecules
Biomarkers
Adme
Biophysics
Lims

Publications

Us Patents

Peptidomimetic Macrocycles

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US Patent:
8399405, Mar 19, 2013
Filed:
Feb 3, 2012
Appl. No.:
13/366113
Inventors:
Huw M. Nash - Concord MA, US
David Allen Annis - Cambridge MA, US
Tomi K. Sawyer - Southborough MA, US
Noriyuki Kawahata - West Roxbury MA, US
Assignee:
Aileron Therapeutics, Inc. - Cambridge MA
International Classification:
A61K 38/02
C07K 2/00
US Classification:
514 11, 514 212, 530300
Abstract:
Biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides; and methods of making and identifying such improved polypeptides.

Peptidomimetic Macrocycles

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US Patent:
8524653, Sep 3, 2013
Filed:
Sep 22, 2009
Appl. No.:
12/564910
Inventors:
Huw M. Nash - Concord MA, US
David Allen Annis - Cambridge MA, US
Tomi K. Sawyer - Southborough MA, US
Noriyuki Kawahata - West Roxbury MA, US
Assignee:
Aileron Therapeutics, Inc. - Cambridge MA
International Classification:
A61K 38/02
C07K 2/00
US Classification:
514 11, 514 212, 530300
Abstract:
Biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides, having good cell penetration properties and reduced binding to human proteins, and methods of identifying and making such improved polypeptides are described.

Novel Heterocycles

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US Patent:
20020103161, Aug 1, 2002
Filed:
Dec 18, 2000
Appl. No.:
09/740267
Inventors:
Manfred Weigele - Cambridge MA, US
George Luke - Clinton CT, US
Tomi Sawyer - Southborough MA, US
Regine Bohacek - Boston MA, US
William Shakespeare - Framingham MA, US
Rajeswari Sundaramoorthi - Watertown MA, US
Yihan Wang - Newton MA, US
David Dalgarno - Brookline MA, US
Chester Metcalf - Boston MA, US
Chi Vu - Arlington MA, US
Noriyuki Kawahata - Medford MA, US
International Classification:
A61K031/675
US Classification:
514/079000, 544/232000
Abstract:
The present invention relates to bone-targeting compounds useful for treating a variety of disorders and conditions, e.g., of bone tissue.

Therapeutic Peptidomimetic Macrocycles

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US Patent:
20090275519, Nov 5, 2009
Filed:
Feb 9, 2009
Appl. No.:
12/378047
Inventors:
Huw M. Nash - Concord MA, US
David Allen Annis - Cambridge MA, US
Tomi K. Sawyer - Southborough MA, US
Noriyuki Kawahata - Somerville MA, US
Jiawen Han - Newton MA, US
Assignee:
AILERON Therapeutics, Inc. - Cambridge MA
International Classification:
A61K 38/16
A61P 35/00
US Classification:
514 13
Abstract:
The present invention provides biologically active peptidomimetic macrocycles for the treatment of cell proliferative disorders such as cancer and immunoproliferative disease.

Biologically Active Peptidomimetic Macrocycles

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US Patent:
20090326192, Dec 31, 2009
Filed:
Apr 8, 2009
Appl. No.:
12/420816
Inventors:
Huw M. Nash - Concord MA, US
Tomi K. Sawyer - Southborough MA, US
Noriyuki Kawahata - Somerville MA, US
Vincent Guerlavais - Arlington MA, US
Matthew Iadanza - Boston MA, US
Assignee:
AILERON THERAPEUTICS, INC. - CAMBRIDGE MA
International Classification:
C07K 2/00
US Classification:
530317, 530345
Abstract:
The present invention provides biologically active peptidomimetic macrocycles with improved properties relative to their corresponding polypeptides. The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.

Methods For Preparing Purified Polypeptide Compositions

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US Patent:
20100210515, Aug 19, 2010
Filed:
Sep 22, 2009
Appl. No.:
12/564909
Inventors:
Huw M. Nash - Concord MA, US
Matthew Iadanza - Somerville MA, US
Christopher Leitheiser - Arlington MA, US
Noriyuki Kawahata - West Roxbury MA, US
Assignee:
AILERON Therapeutics, Inc. - Cambridge MA
International Classification:
A61K 47/48
C07K 1/14
C07K 14/00
C12Q 1/00
US Classification:
514 9, 530300, 435 4
Abstract:
The present invention relates to purified peptidomimetic macrocycles. The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.

Peptidomimetic Macrocycles With Improved Properties

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US Patent:
20100298201, Nov 25, 2010
Filed:
Nov 24, 2009
Appl. No.:
12/625533
Inventors:
Huw M. Nash - Concord MA, US
David Allen Annis - Cambridge MA, US
Tomi K. Sawyer - Southborough MA, US
Noriyuki Kawahata - Somerville MA, US
Assignee:
AILERON Therapeutics, Inc. - Cambridge MA
International Classification:
A61K 38/17
C07K 14/435
A61P 35/00
A61P 19/02
A61P 11/06
A61P 3/10
A61P 25/00
A61P 9/00
A61P 5/00
US Classification:
514 11, 530402
Abstract:
The present invention provides biologically active peptidomimetic macrocycles with improved properties relative to their corresponding polypeptides. The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.

Biologically Active Peptidomimetic Macrocycles

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US Patent:
20110144303, Jun 16, 2011
Filed:
Oct 13, 2009
Appl. No.:
12/578552
Inventors:
Huw M. Nash - Concord MA, US
Tomi K. Sawyer - Southborough MA, US
Noriyuki Kawahata - Somerville MA, US
Vincent Guerlavais - Arlington MA, US
Matthew Iadanza - Boston MA, US
Assignee:
AILERON Therapeutics, Inc. - Cambridge MA
International Classification:
C07K 1/113
US Classification:
530345
Abstract:
The present invention provides biologically active peptidomimetic macrocycles with improved properties relative to their corresponding polypeptides. The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.
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Noriyuki H Kawahata from Wayland, MA, age ~57 Get Report