Inventors:
Nordin Zeidner - Fort Collins CO, US
Marc Dolan - Fort Collins CO, US
Donald Champagne - Athens GA, US
Assignee:
of Health and Human Services, Centers for Disease Control and Prevention - Atlanta GA
International Classification:
A61K 38/46
A61P 31/04
A01P 1/00
A01N 37/18
Abstract:
The present invention relates to reagents and methods for the modulation of viability of bacteria. A process is provided wherein a protein sequence from saliva effective in reducing the viability of gram positive, gram negative, or acid-fast bacteria and spirochetes including is administered. The inventive protein from saliva has utility as a therapeutic for the treatment of an organism infected with bacteria, particularly the spirochete