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Nico P Ghilardi

from South San Francisco, CA
Age ~54
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Also known as:
Nico Patrik Ghilardi, Nico P Ghi, Nico Thilardi
Phone and address:
172 Valleyview Way, South San Francisco, CA 94080
Related to:
Deborah Rae Leahy, 60Marie Kelly, 58Beth Surprenant, 58Mark Vita, 60Kelley Reilly, 49
Connected to:
Adrianna L Ghilarducci, 42Anita M Ghilardi, 80Brian S Ghilarducci, 41Daniel A Ghilardi, 56Lisa A Ghilarducci, 30Pamela R Ghilardi, 65Philip Ghilarducci, 39Yvonne M Ghilardi, 71Arvind Ghildiyal, 34Vinod Ghildiyal, 69

Nico Ghilardi Phones & Addresses

  • 172 Valleyview Way, S San Fran, CA 94080
  • South San Francisco, CA
  • Tempe, AZ
  • 1329 Terrace Dr, Millbrae, CA 94030 (650) 873-2037
  • San Mateo, CA
  • 1329 Terrace Dr, Millbrae, CA 94030

Resumes

Resumes

Nico Ghilardi Photo 1

South San Francisco, California

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Location:
172 Valleyview Way, South San Francisco, CA 94080
Industry:
Biotechnology
Work:
Genentech
Associate Director and Principal Scientist
Genentech
Associate Director and Senior Scientist
Genentech
Senior Scientist
Genentech Jan 2005 - May 2011
Scientist
Genentech Apr 2003 - Jan 2005
Associate Scientist
Education:
University of Basel 1995 - 1999
Skills:
Immunology
Molecular Biology
Biotechnology
Drug Discovery
Cell
Drug Development
Elisa
Flow Cytometry
Cell Culture
Life Sciences
Genomics
Antibodies
In Vivo
Pcr
Scientific Writing
Animal Models
Lifesciences
Monoclonal Antibodies
Biomarkers
Therapeutics
Western Blotting
Cell Based Assays
Qpcr
Signal Transduction
Cell Biology
Hematology
Dna
Facs
Molecular Cloning
Languages:
German
French
Latin
English
Nico Ghilardi Photo 2

Nico Ghilardi

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Publications

Us Patents

Novel Type-1 Cytokine Receptor Glm-R

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US Patent:
20070136829, Jun 14, 2007
Filed:
Oct 11, 2006
Appl. No.:
11/548639
Inventors:
Nico Ghilardi - Millbrae CA, US
Frederic De Sauvage - Foster City CA, US
Audrey Goddard - San Francisco CA, US
Paul Godowski - Hillsborough CA, US
J. Grimaldi - San Francisco CA, US
Austin Gurney - San Francisco CA, US
William Wood - Cupertino CA, US
International Classification:
A01K 67/027
C12Q 1/68
G01N 33/53
G01N 33/567
C07H 21/04
C12P 21/06
C07K 14/705
US Classification:
800014000, 435006000, 435007200, 435069100, 435320100, 435325000, 530350000, 530388220, 536023500, 435007100, 435353000
Abstract:
The present invention is directed to novel polypeptides and variants thereof of GLM-R polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Also provided are methods for detecting agents that modulate the activity of GLM-R. Also provided are methods for diagnosing and for treating disorders characterized by the over or under abundance of monocytes or macrophages.

Il-17A/F Heterologous Polypeptides And Therapeutic Uses Thereof

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US Patent:
20070160576, Jul 12, 2007
Filed:
Nov 29, 2006
Appl. No.:
11/606192
Inventors:
David Arnott - San Mateo CA, US
Mercedesz Balazs - Hayward CA, US
Nico Ghilardi - Millbrae CA, US
Austin Gurney - San Francisco CA, US
Philip Hass - Moss Beach CA, US
Sarah Hymowitz - San Francisco CA, US
James Lee - San Bruno CA, US
Wenjun Ouyang - Foster City CA, US
Melissa Starovasnik - San Francisco CA, US
Yan Wu - Foster City CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
A61K 38/20
C07H 21/04
C12P 21/04
C07K 14/54
C07K 16/24
US Classification:
424085200, 435069520, 435320100, 435325000, 530351000, 536023500, 530388230
Abstract:
The present invention is directed to a novel naturally occurring human cytokine that is comprised of a heterodimer of interleukin-17 and interleukin-17F designated herein as interleukin 17A/F (IL-17A/F). Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, specific antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.

Nucleic Acid Encoding Novel Type-1 Cytokine Receptor Glm-R

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US Patent:
20070174922, Jul 26, 2007
Filed:
Feb 24, 2003
Appl. No.:
10/373512
Inventors:
Nico Ghilardi - Millbrae CA, US
Frederic de Sauvage - Foster City CA, US
Audrey Goddard - San Francisco CA, US
Paul Godowski - Hillsborough CA, US
J. Grimaldi - San Francisco CA, US
Austin Gurney - Belmont CA, US
William Wood - Hillsborough CA, US
International Classification:
A01K 67/027
C12Q 1/68
G01N 33/567
C07H 21/04
C12P 21/06
C12N 5/06
C07K 14/705
C07K 16/28
US Classification:
800014000, 435006000, 435069100, 435320100, 435354000, 530350000, 530388220, 536023500, 435007200
Abstract:
The present invention is directed to novel polypeptides having sequence similarity to Interleukin 6 receptor and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

Compositions And Methods For Treatment Of Microbial Disorders

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US Patent:
20090202475, Aug 13, 2009
Filed:
Nov 7, 2008
Appl. No.:
12/291380
Inventors:
Alexander R. Abbas - San Carlos CA, US
Nico P. Ghilardi - Millbrae CA, US
Zora Modrusan - Fremont CA, US
Dimitry M. Danilenko - Millbrae CA, US
Frederic J. De Sauvage - Foster City CA, US
Wenjun Ouyang - Foster City CA, US
Patricia A. Valdez - Kensington MD, US
Yan Zheng - Fremont CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
A61K 38/20
A61K 38/16
C12N 5/00
A61K 38/02
A61K 31/7052
A61K 39/395
A61P 31/00
C07K 14/54
C07K 14/00
US Classification:
424 852, 514 12, 435375, 514 2, 4241341, 4241581, 4241451, 4241331, 530351, 530350
Abstract:
The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.

Methods For Treating Autoimmune Disorders

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US Patent:
20090280082, Nov 12, 2009
Filed:
Feb 27, 2009
Appl. No.:
12/395550
Inventors:
Nico GHILARDI - Millbrae CA, US
Frederic DeSauvage - Foster City CA, US
International Classification:
A61K 38/20
A61K 39/395
C12N 5/00
A61K 38/16
C12Q 1/68
C07K 16/00
A61P 37/06
US Classification:
424 852, 4241731, 435375, 4241441, 4241331, 4241351, 514 12, 435 6, 5303881, 435346, 4241581
Abstract:
The present invention relates to methods for treating autoimmune disorders. In an embodiment, the invention is directed to a method for treating an autoimmune disorder comprising administering a TCCR agonist. In an embodiment, the autoimmune disorder is at least partially mediated by a Th1 response. In an embodiment, the autoimmune disorder is at least partially mediated by CD8 T-cell proliferation.

Use Of Il-27 Antagonists To Treat Lupus

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US Patent:
20100297127, Nov 25, 2010
Filed:
Apr 8, 2010
Appl. No.:
12/756871
Inventors:
Nico P. GHILARDI - Millbrae CA, US
Marcel L. BATTEN - Enmore, AU
Jason A. HACKNEY - Palo Alto CA, US
International Classification:
A61K 39/395
A61K 38/02
A61K 31/713
A61P 37/00
C12Q 1/68
US Classification:
4241361, 4241581, 4241451, 4241331, 514 11, 514 44 A, 435 6
Abstract:
This invention relates to methods of treating the autoimmune disorder lupus with IL-27 antagonists, as well as articles of manufacture comprising IL-27 antagonists. The invention also relates to methods and kits for identifying patients that are likely to respond to an IL-27 antagonist treatment.

Il-17A/F Heterologous Polypeptides And Therapeutic Uses Thereof

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US Patent:
20110256126, Oct 20, 2011
Filed:
Mar 2, 2011
Appl. No.:
13/039201
Inventors:
David P. Arnott - San Mateo CA, US
Mercedes Z. Balazs - Hayward CA, US
Nico Ghilardi - Millbrae CA, US
Austin L. Gurney - San Francisco CA, US
Philip E. Haas - Moss Beach CA, US
Sarah Hymowitz - San Francisco CA, US
James M. Lee - San Bruno CA, US
Wenjun Ouyang - Foster City CA, US
Melissa A. Starovasnik - San Francisco CA, US
Yan Wu - Foster City CA, US
International Classification:
A61K 39/395
A61P 7/06
A61P 7/02
A61P 13/12
A61P 25/00
A61P 1/00
A61P 17/00
A61P 17/06
A61P 11/06
A61P 37/06
A61P 19/02
A61P 31/14
US Classification:
4241331, 4241391
Abstract:
The present invention is directed to a novel naturally occurring human cytokine that is comprised of a heterodimer of interleukin-17 and interleukin-17F designated herein as interleukin 17A/F (IL-17A/F). Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, specific antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.

Methods For Treatment Of Microbial Disorders

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US Patent:
20110280828, Nov 17, 2011
Filed:
May 20, 2011
Appl. No.:
13/112850
Inventors:
Alexander R. ABBAS - San Carlos CA, US
Nico P. Ghilardi - Millbrae CA, US
Zora Modrusan - Fremont CA, US
Dimitry M. Danilenko - Millbrae CA, US
Frederic J. De Sauvage - Foster City CA, US
Wenjun Ouyang - Foster City CA, US
Patricia A. Valdez - Kensington MD, US
Yan Zheng - Fremont CA, US
International Classification:
A61K 38/20
A61P 29/00
A61P 31/04
US Classification:
424 852
Abstract:
The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.
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Nico P Ghilardi from South San Francisco, CA, age ~54 Get Report