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Nevin M Witman

from Watertown, MA
Age ~42
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Related to:
Tonette Weidenheimer, 55Leonard M WellerRyan Hoffert, 51Lisa Hoffert, 57Kimberly A Readinger, 42Melissa Delbo, 47Amanda Readinger, 38
Connected to:
Cindy L Witman, 68Clarence H Witman, 92Destiny Witman, 37Frank E Witman, 112James G Witman, 37Jessica A Witman, 51John M Witman, 40Kathy L Witman, 55William C Witman, 69Anna A Witmer, 60

Nevin Witman Phones & Addresses

  • Watertown, MA
  • Newton, MA
  • State College, PA
  • 4910 Oley Turnpike Rd, Reading, PA 19606 (610) 779-2672 (610) 779-5618
  • 10 34Th St, Reading, PA 19606 (610) 779-5618

Publications

Us Patents

Mesenchymal Stem Cells Or Stromal Cells Harboring Modified Rnas Encoding Vegf And Bmp Polypeptides

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US Patent:
20210052776, Feb 25, 2021
Filed:
Jul 1, 2020
Appl. No.:
16/918979
Inventors:
Nevin Witman - Reading PA, US
Kenneth R. Chien - Cambridge MA, US
Wei Fu - Shanghai, CN
International Classification:
A61L 27/38
A61K 35/28
A61K 35/51
A61K 35/50
A61K 9/00
A61P 19/00
C07K 14/51
C07K 14/475
C12N 5/0775
A61L 27/54
Abstract:
This disclosure relates to compositions including mesenchymal stem or stromal cells (MSCs) that harbor one or more modified RNA molecules encoding a bone morphogenetic protein (BMP), e.g., human BMP, and one or more modified RNA molecules encoding vascular endothelial growth factor (VEGF), e.g., human VEGF or VEGF-A, or first and second separate pluralities of MSCs, wherein each MSC in the first plurality of MSCs harbors one or more modified RNA molecules encoding BMP, and wherein each MSC in the second plurality of MSCs harbors one or more modified RNA molecules encoding VEGF; and a carrier, e.g., a solid or semi-solid carrier. The disclosure also relates to methods and uses of these compositions to treat bone defects.
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Nevin M Witman from Watertown, MA, age ~42 Get Report