US Patent:
20030013178, Jan 16, 2003
Inventors:
Edward Ginns - Bethesda MD, US
Ellen Sidransky - Bethesda MD, US
Suzanne Winfield - Rockville MD, US
Nahid Tayebi - Potomac MD, US
Brian Martin - Rockville MD, US
Assignee:
Department of Health and Human Sevices, c/o National Institutes of Health
International Classification:
C12N009/24
C07H021/04
US Classification:
435/200000, 435/069100, 435/320100, 536/023200
Abstract:
The present invention provides the discovery and isolation of the nucleotide sequence of the human clk2, the human propin1, and the human cote1 genes that are located within the glucocerebrosidase gene locus. Also provided by the present invention are proteins or polypeptides encoded by those genes, nucleic acids encoding those polypeptides, and antibodies to those proteins. Further provided by the present invention are nucleic acids of the same apparent molecular size as the propin1 and cote1 gene regions and which have the same restriction pattern as the wild-type genes.
