US Patent:
20080268067, Oct 30, 2008
Inventors:
Rodolfo R. Llinas - New York NY, US
Mutsuyuki Sugimori - New York NY, US
Francisco Urbano - Brooklyn NY, US
International Classification:
A61K 33/30
A61K 31/045
G06G 7/58
A61K 33/16
A61P 25/08
A61K 31/05
A61K 31/135
A61K 31/02
A61K 31/4045
A61K 31/137
A61K 31/381
A61K 31/4422
A61K 31/4168
A61K 31/451
A61K 31/517
A61K 31/138
A61K 31/4525
A61K 31/66
A61K 31/08
A61K 31/4164
A61P 25/28
A61P 25/02
G01N 33/566
A61K 31/515
US Classification:
424641, 514724, 703 11, 436501, 514271, 424676, 514731, 514400, 514647, 514722, 514743, 514108, 514415, 514321, 514652, 51425941, 514327, 514356, 514655
Abstract:
This invention relates to methods of inhibiting a Ca3 calcium channel in a cell using a C-Calkyl alcohol, or mixtures thereof. This invention further relates to methods of treating a thalamocortical dysrhythmia disorder in a mammal and for treating a neurological disorder in a mammal associated with the thalamocortical dysrhythmia using a C-Calkyl alcohol, a lipophilic molecule with a partition coefficient substantially similar to that of a C-Calkyl alcohol, or mixtures thereof, or a pharmaceutical composition comprising the same.