Resumes
Resumes
Mrinal Sanyal Phones & Addresses
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30 Village Pond Rd, Guilford, CT 06437 (203) 453-0553
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Branford, CT
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30 Village Pond Rd, Guilford, CT 06437 (203) 240-4468
Work
Position:
Retired
Education
Degree:
Graduate or professional degree
Publications
Us Patents
Collection Of Biological Products From Human Accessory Reproductive Organs By Absorbent Systems
View pageUS Patent:
61266167, Oct 3, 2000
Filed:
Jun 21, 1999
Appl. No.:
9/337599
Inventors:
Mrinal K. Sanyal - Guilford CT
International Classification:
A61B 1000
A61F 544
A61F 544
US Classification:
600562
Abstract:
A cervical collection device (20) for collecting uterine and cervical secretions for medical diagnostic purposes. The cervical collection device (20) is placed over the cervical opening (14). Collection device (20) includes an outer elastomeric receptacle (22) of a hemispherical shape having a collection capsule or pad (26) fitting thereon. Collection pad (26) includes an inner layer or core (28) of absorbent material and an outer water-resistant cover (32). Collection member (26) has an outer convex surface conforming to the inner surface of the elastomeric receptacle (22). Receptacle (22) has an outer rim (24) arranged for fitting over the cervical opening (14) for removable securement of collection device (20) to a user. Inner layer (28) may be formed of various materials and impregnated with selected substances.
Self-Recovery Of Preimplantation Stage Human Embryos And Characterization Of Their Morphological, Physiological And Genomic Features
View pageUS Patent:
20200367868, Nov 26, 2020
Filed:
Aug 7, 2020
Appl. No.:
16/987788
Inventors:
Mrinal K. Sanyal - Guilford CT, US
International Classification:
A61B 10/02
G01N 33/574
C12Q 1/6886
G01N 33/574
C12Q 1/6886
Abstract:
This invention provides devices and methods for self-administered noninvasive retrieval of biological materials of the uterus and cervix, and preimplantation stage embryos. The procedure uses a Uterine Device, with a receptacle of variable volume, a controller configured to change the volume of the receptacle cavity, a flexible pouch for generation of suction to facilitate their retrieval, and an Absorption Capsule, which is a surface for collection of the above biological materials. The biological materials retrieved include cells and secretions, directly from the site of pathology, not metabolized or diluted in the body fluids, allow comprehensive analysis of various biomarkers of diseases and disorders of reproduction. Information generated by analyzing these biological materials permits early diagnosis and assessment of prognosis of diseases and disorders of the female reproductive organs, irregularities of pregnancy, anomalies of the fetus in utero, and microbial infections. The preimplantation stage embryos are recovered from normal subjects or those received treatment of gonadotrophins and/or other methods for induction of ovulation or superovulation to improve the yield of ovulated oocytes (ova). Multiple ova released from the ovaries travel through the fallopian tubes, which may be fertilized with sperms made available by artificial or normal insemination (copulation). The fertilized embryos divide and differentiate further into free preimplantation stage embryos at morula- and blastocyst-stages are deposited on the Absorption Capsule. These embryos, retrieved from the Absorption Capsule and may be processed by a variety of methods routinely utilized in the Assisted Reproductive procedures, including, screening for various genomic diseases, karyotype errors of trisomy and other chromosomal anomalies, and deleterious mutations. The screening procedures may involve Preimplantation Genetic Diagnosis (PGD) and Trophectoderm biopsy methods. Normal embryos free of disease potential are transferred to the mothers or surrogates for further in utero development. These procedures allow prevention of human birth defects and pre- and post-natal genomic diseases by selection of disease-free normal embryos for further in utero development, and possible cure of genomic diseases at this stage, in the future.
Retrieval Of Biological Materials From The Human Uterus, Ovary And Cervix By Suction
View pageUS Patent:
20180064425, Mar 8, 2018
Filed:
Nov 7, 2017
Appl. No.:
15/805796
Inventors:
Mrinal K. Sanyal - Guilford CT, US
International Classification:
A61B 10/00
C12Q 1/68
C12Q 1/68
Abstract:
The invention provides devices and methods for self-administered noninvasive retrieval of biological materials of the uterus and/or cervix and preimplantation stage embryos. The cervical device comprises a receptacle with a variable volume receptacle cavity, a controller configured to change the volume of the receptacle cavity, a surface for collection of biological materials, and a flexible pouch for generation of suction to facilitate efficient retrieval of biological materials. The biological materials retrieved include various biomarkers of diseases and disorders of reproduction, are directly isolated from a site of pathology, and are not metabolized or diluted. Information generated by analyzing these biological materials permits early diagnosis and prognosis assessments of disease and disorders of the female reproductive organs, irregularities of pregnancy, anomalies of the fetus in utero, and microbial infections.
Retrieval Of Biological Materials From The Human Uterus, Ovary And Cervix By Suction
View pageUS Patent:
20150065379, Mar 5, 2015
Filed:
Aug 28, 2014
Appl. No.:
14/471433
Inventors:
Mrinal K. Sanyal - Guilford CT, US
International Classification:
A61B 10/00
G01N 33/574
G01N 33/574
US Classification:
506 9, 435 612, 506 7, 435 792, 435 611, 600580, 600572, 600300
Abstract:
The invention provides devices and methods for self-administered noninvasive retrieval of biological materials of the uterus and/or cervix. The cervical device comprises a receptacle with a variable volume receptacle cavity, a controller configured to change the volume of the receptacle cavity, a surface for collection of biological materials, and a flexible pouch for generation of suction to facilitate efficient retrieval of biological materials. The biological materials retrieved include various biomarkers of diseases and disorders of reproduction, are directly isolated from a site of pathology, and are not metabolized or diluted. Information generated by analyzing these biological materials permits early diagnosis and prognosis assessments of disease and disorders of the female reproductive organs, irregularities of pregnancy, anomalies of the fetus in utero, and microbial infections.